INSIGHTS ON CRITICAL ENVIRONMENTS
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![iStock-1018468948-microscope-lab]( "Confessions Of A Microbiologist: What I Wish I Had Known For Our Facility Shutdown")
Confessions Of A Microbiologist: What I Wish I Had Known For Our Facility ShutdownFacility shutdowns often compromise contamination control strategies. Transitioning from manual cleaning to automated bio-decontamination ensures a more effective facility restart, eliminating persistent mold risks.
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![GettyImages-1218745370 cleanroom, disinfecting, lab]( "Your Environmental Monitoring Can't Be Your Only Line Of Defense")
Your Environmental Monitoring Can't Be Your Only Line Of DefenseEnvironmental monitoring (EM) is essential, but it’s only part of the picture. Discover why a proactive contamination control strategy is key to keeping your cleanroom truly audit-ready.
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![Pipette With Cell Culture Plate-GettyImages-520238063]( "Automation-Assisted Washing Of Multicellular 3D Spheroids")
Automation-Assisted Washing Of Multicellular 3D SpheroidsAutomated washing of 3D spheroids improves consistency, reduces cell loss, and streamlines staining workflows. See how this approach enhances reproducibility and throughput in microplate-based assays.
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![GettyImages-1572385009 production, facility, manufacturing, pharma]( "From IND To NDA: The Role Of The Kilo Lab In A Seamless Scaleup")
From IND To NDA: The Role Of The Kilo Lab In A Seamless ScaleupTo derisk your manufacturing, work with an outsourcing partner that prioritizes the kilo lab as a space to develop a proven, robust, and reliable workflow from clinical to commercial scale.
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cGMP Vs GMP In Cleanrooms: Understanding The Differences That Matter6/19/2026
Differentiating GMP from cGMP helps facility teams design cleanrooms that meet modern contamination controls, process flows, and regulatory standards.
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Implementing Rapid Microbial Identification In Biotherapy Manufacutring5/27/2025
Learn about rapid microbial identification strategies that enhance environmental monitoring and compliance with regulatory requirements for your manufacturing processes.
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Sustainability By Design In API Manufacturing7/29/2025
Explore the urgent need for sustainability in small molecule API manufacturing, as well as reveal regulatory drivers, green chemistry innovations, and practical strategies to reduce emissions.
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0.45 m/s ±20% At Working Position In Closed Sterility Testing Isolators: Requirement Or Convention?2/19/2026
Balance compliance and efficiency in sterility testing. Explore how a risk-based approach to airflow and isolator technology aligns with Annex 1 while optimizing contamination control.
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A Risk-Based Decision Framework For Selecting Aseptic Barrier Technologies3/20/2026
EU GMP Annex 1 requires a risk-based approach to selecting Isolators or RABS. This framework evaluates human intervention and decontamination to ensure robust sterility assurance.
CRITICAL ENVIRONMENT SOLUTIONS
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![Viruses On Red Background GettyImages-1044016410]( "Cleaning And Disinfecting For Viruses And Other Pathogens")
Per Center for Disease Control (CDC) guidelines for cleaning and disinfecting viruses and other pathogens, any form of disinfection necessarily follows cleaning. The process of cleaning will remove any residues that might shield any virus or pathogen from the disinfection step that comes next. Disinfection, following thorough cleaning and rinsing, can be done with bleach solutions, 70% alcohol solutions, or other products with EPA-approved emerging viral pathogens claims. As outlined by CDC, bleach solutions should reside on surface for at least one minute and can be made as follows:
- 5 tablespoons (1/3rd cup) bleach per gallon of water, or
- 4 teaspoons bleach per quart of water
An excellent cleaning and wiping solution can be made with 0.5% (0.75- 1.5 oz/gal or 5 mL/L) Alconox® Powdered Precision Cleaner or Liquinox® Critical Cleaning Liquid Detergent, depending on preference for powder or liquid concentrate, respectively. Following which, per the CDC guidelines, wipe with the above bleach solution or other disinfectant solution. Allow wiped-down surfaces to sit for several minutes before rinsing to complete the disinfection.
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Extract Technology aseptic isolators are designed to allow operators to perform aseptic processes in a sterile environment providing assurance of process integrity.
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![Peridox RTU sterile]( "Cleanroom Disinfectants & Solutions")
Contec offers a wide range of specially formulated chemicals for the cleaning and disinfection of critical and sterile environments. From hydrogen peroxide solutions and IPA, to fast-acting validated sporicidal and broad-spectrum disinfectants, Contec has the cleaning solutions you need.
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![Laboratory Cleaning GettyImages-1218973560]( "Functional VPA Copolymer")
Discover how advanced VPA copolymer solutions can help accelerate innovation and deliver high-performance materials tailored to your most demanding applications.
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![GettyImages-1326891881 cleanroom, lab]( "Particle Loss Studies")
Ensure Compliance. Safeguard Sterility. Drive Manufacturing Excellence.
FREE CLEANING VALIDATION E-BOOK
Learn how to employ science-, risk-, and statistics-based approaches to cleaning and cleaning validation at your facility with this free, 100-page e-book, written by a global team of cleaning validation experts, pharmaceutical toxicologists, statisticians, and Six Sigma professionals.
