Exposure to pharmaceuticals in compounding environments can lead to a number of health risks for pharmaceutical employees and patients. These health risks can range from contact with hazardous waste materials, harmful particulates during pressure changes or even transmissible disease.
Food manufacturers typically install an x-ray inspection system at the end of the production line, although it can be installed at any point during the production process. But, which are the best locations for x-ray inspection? Where are the critical control points to ensure the highest levels of product safety? Should x-ray inspection be at the beginning of the production line, where the raw materials arrive, at some intermediate stage, or at the end of the line before products are shipped out? Or would product safety and quality be better served by installing x-ray systems at more than one critical control point? This white paper addresses these questions to help you understand the most effective locations of critical control points.
In recent years, container closure integrity (CCI) testing has steadily moved up the pharmaceutical manufacturing agenda. Latest research has shown that not only ampoules are prone to CCI defects. Other primary packaging types such as vials, cartridges and syringes equally require thorough testing, especially when filled with lyophilized products. Consequently, the United States Pharmacopeia (USP) has been revising its General Chapter 1207, calling for more quantitative, validated CCI test methods. A significant shift is expected towards non-destructive technologies.
The Center for Regenerative Medicine (ZRM) in Zurich is part of the Center for Clinical Research (ZKF), which is supported by the University Hospital Zurich and the University of Zurich. The ZRM combines basic biomedical research and clinical applications in the field of regenerative medicine. Regenerative medicine uses cell-based technologies for the treatment of tissue and organ damage (e. g. growing skin for burn victims).
The generics market has taken off in recent years due to numerous patent expirations for brand-name companies. In light of this, pharmaceutical manufacturers, insurance companies and consumers, in search of significant cost savings, have turned towards the generics industry.