INSIGHTS ON DRUG DEVELOPMENT
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Aggregate Analysis Of Tirzepatide
A new size exclusion method effectively analyzes Tirzepatide aggregates, demonstrating robust separation and reproducibility with minimal need for organic solvents or acidic modifiers.
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Column Selection For RPLC-UV Impurity Analysis
Explore the performance of four column chemistries for RPLC-UV impurity analysis of liraglutide and semaglutide, which offers practical guidance for method development in peptide-based therapeutics.
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Cell Culture Media Filtration: Evaluating Cell Culture Performance
Cell culture performance remained consistent across PES and PVDF filters, even under worst-case filtration conditions. Discover a practical framework for evaluating membrane impact on CHO cell growth.
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Expanding Opportunities For Inhaled Drug Delivery
Review the challenges and intricacies of effectively delivering drugs to the lung and the advantages of using nanoparticles and gentle particle processing techniques to enable delivery of sensitive drugs.
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How Peptides Became Cornerstones Of Modern Medicine5/18/2026
Peptides evolved from early chemical discoveries to transformative therapies, culminating in GLP‑1 drugs that highlight their versatility, precision, and expanding role across modern medicine.
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Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies7/15/2026
In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
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The Body As A Bioreactor – Delivering The Vision8/8/2026
Making the body a bioreactor requires precise delivery to selected cells. See how lipid nanoparticles, manufacturing science, and biology are converging to overcome biological barriers and improve the targeting of advanced therapies.
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Eliminate Risk From Your Viral Vector Tech Transfers12/5/2025
Explore strategies to simplify viral vector tech transfers, reduce risk, and maintain quality under tight timelines, as well as a case study that demonstrates how to streamline this critical process.
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Cell Retention Technology And Specialized Cell Culture Media8/11/2025
Explore how perfusion technology is transforming upstream bioprocessing by boosting productivity, reducing costs, and enabling process intensification while overcoming cell retention challenges.
DRUG DEVELOPMENT SOLUTIONS
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The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur.
Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes.
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Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
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The journey of a GLP-1 receptor agonist (GLP-1 RA) molecule is complex.
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Powerful tools for characterizing protein-protein interactions, structural stability, and formulation compatibility.
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Orbis provides innovative taste-making and controlled release solutions for oral and injectable pharmaceutical products.