INSIGHTS ON DRUG DEVELOPMENT
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![assessing ta webinar thumb]( "Assessing Production And Stability Of Antibody Drug Conjugate Platforms")
Assessing Production And Stability Of Antibody Drug Conjugate PlatformsADCs with similar antibody sequences can behave differently due to linker and payload choices. Analytical tools reveal structural and stability differences critical to therapeutic performance.
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![GettyImages-1224404114-mortar-crushing-pills-bottle-pharmacy]( "Advantages Of Spray-Dried Mannitol In Roll Compaction")
Advantages Of Spray-Dried Mannitol In Roll CompactionPharmaceutical excipients like mannitol enhance formulation stability, flowability, and compressibility, which are crucial for robust tablets. Read how these properties improve patient compliance.
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![iStock-1200587353-skin-skincare-lotion-topical-cream]( "Human Skin Explant Model For The Investigation Of Topical Therapeutics")
Human Skin Explant Model For The Investigation Of Topical TherapeuticsLearn more about an ex vivo cultured human skin explant model in which pathological tissue integrity, barrier function, and metabolic stability have been characterized over time.
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![Cleanroom Scientists Using Tablet GettyImages-1341292153]( "Is Mannitol Hemihydrate Detrimental To Protein Stability?")
Is Mannitol Hemihydrate Detrimental To Protein Stability?Maintaining an amorphous excipient matrix is crucial for protein stability. Learn about the importance of storage conditions in managing mannitol hemihydrate dehydration and ensuring protein stability.
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3D Neurospheres In Healthy And Alzheimer's: iPSC-Derived Neurons4/4/2025
Explore how different ApoE alleles influence Alzheimer's Disease risk using iPSC-derived neurons as well as gain insights into AD mechanisms and potential therapies.
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Efficacy Screening Of Antibody-Drug-Conjugates By Surface Plasmon Resonance6/3/2024
Rapid screening of ADC affinity using surface plasmon resonance provides preliminary efficacy data in comparing antigen binding affinity with selected linkers and payloads to the non-conjugated antibody.
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Little Patients, Big Challenges: Developing Pediatric Formulations5/12/2025
Explore the development of high-quality, child-friendly oral formulations, as well as learn about new testing requirements for impurities and innovative approaches to creating age-appropriate medications.
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Quantification Of Semaglutide With A Reliable Analytical Method7/17/2025
Explore a validated LC-MS/MS method for precise Semaglutide quantification in plasma, which features enhanced sensitivity, peak definition, and reproducibility using innovative technologies.
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How A Privately Owned CDMO Is Transforming Client Expectations5/16/2024
Finding a partner with flexible services and a strong emphasis on building long-term client relationships can help ensure success for your pharmaceutical product.
DRUG DEVELOPMENT SOLUTIONS
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![Quotient Sciences - Drug Synthesis]( "Drug Substance Synthesis And Manufacturing")
We take an agile and flexible approach with our customers programs, offering bespoke drug substance synthesis and manufacturing, helping to accelerate molecules from candidate selection to clinical proof-of-concept and onwards towards commercial scale.
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![RS-DSC]( "Microcalorimetry: RS-DSC, DSC & ITC")
By harnessing cutting-edge microcalorimetry technology, researchers can unravel the complexities of molecular interactions, paving the way for groundbreaking discoveries in drug development.
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![Lab GettyImages-1354171893]( "Biologics Quality Control: A Critical Component Of Development And Production")
Quality control is a critical component for ensuring safety, efficacy, and consistency in the development and production of biologics. This comprehensive list of strategies, techniques, workflows, and best-in-class products for developing biopharmaceuticals can help you navigate the complexities of biologics and simplify the manufacturing process. Improve your quality control procedures and optimize your biologics production process with tools and expertise relied upon by researchers worldwide.
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![leica-microsystems-lmd6-hero]( "Laser Microdissection Microscope - Isolate Single Cells")
LMD 6 Laser Microdissection Microscope
Dissection Perfection
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.
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![molecular-devices-clone-select-imager-fl]( "High-Speed Fluorescence And White Light Imaging With The CloneSelect Imager")
Next-generation fluorescent imaging solution for the assurance of monoclonality and automated confluence across diverse cell types
Demonstrating that cell lines are monoclonal – or that a gene was edited as expected – can be a time-consuming and highly-subjective process when relying on conventional technologies. The CloneSelect® Imager and CloneSelect® Imager FL are a high-throughput automated solutions for imaging and analyzing mammalian cells. Tracking the formation of a colony from a single cell is effortless as barcoded plates are tracked over time. Automated acquisition and analysis provides accurate, objective, and consistent results.
