INSIGHTS ON DRUG DEVELOPMENT
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Measuring Thermodynamic Parameters In The Drug Development Process
Join Dr. Ladbury to explore how thermodynamic data can enhance our understanding of protein-ligand interactions and how it is crucial for optimizing drug efficacy and safety in pharmaceutical development.
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Towards A More Predictive Model Of Human Biology: A Fireside Chat
This presentation explores the implications of the FDA Modernization Act 2.0, the significance of predictive validity in drug discovery, the efficacy of the Emulate human Liver-Chip, and more.
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Benchmarking Filtration Performance Of TFF Cassettes
Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.
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Getting The Most Out Of Cell-Based Assays With The Optimal Read Function
Gain insight into a whole-well fluorescence analysis that improves sensitivity and reproducibility in cell-based assays by accounting for uneven cell distribution.
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API In Capsule Vs. The Lost Art Of Formulation Development11/5/2025
API-in-capsule offers a fast path for early clinical data, but it can't eliminate the need for full formulation development. Weighing the potential for higher total development time and cost is critical.
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Strategies For The Development Of Safe And Effective Pediatric Formulations5/12/2025
Medicines for infants and children face unique formulation challenges. Learn about the key considerations, including developmental physiology, age specifics, palatability, ease of administration, and precise dosing.
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Microflow Columns Boost GLP-1 Sensitivity And Reduce Solvent5/7/2026
Microflow chromatography offers a practical way to boost GLP‑1 assay sensitivity while cutting solvent use. See how 1.0 mm columns improve peak response without sacrificing chromatographic performance.
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Efficiently Optimize Your Workflow With Single-Use Chromatography11/4/2025
Explore how low-volume purification can be done more efficiently in GMP settings with a live system demo and customer insights on optimizing workflows with single-use chromatography.
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Comprehensive Workflow For The Quantification Of Peptides And Proteins7/29/2025
Biologics are transforming medicine, with semaglutide leading the way. Discover how an automated LC-MS/MS workflow enables high-sensitivity quantification of peptides in plasma.
DRUG DEVELOPMENT SOLUTIONS
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LMD 6 Laser Microdissection Microscope
Dissection Perfection
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.
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Calculators & Predictors for LogP, LogD, pKa, Aqueous Solubility, and more…
The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.
ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.
- Predict aqueous solubility,* boiling point, logD,* logP,* pKa,* Sigma, and other molecular descriptors for organic compounds, from structure
- Evaluate the calculated results with sorting, plotting tools
- Assess the reliability of predicted physicochemical property values
- Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
- Train predictors with experimental data to better reflect novel chemical space
- Include custom models and in-house prediction algorithms
*Models are trainable with experimental data
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Filterless readers provide consistent results with steady temperature regulation
The SpectraMax® ABS and ABS Plus absorbance microplate readers provide the flexibility, sensitivity, and convenience for a wide range of assays such as ELISAs, microbial growth, and protein quantitation. Both readers feature an 8-channel read head for fast reads and a subset feature, the temperature independent PathCheck sensor that automatically normalizes and ensures accurate absorbance values by detecting pipetting errors. Combined with a wide application base, industry-leading SoftMax® Pro Software and validation tools, these readers fit in every lab and every budget.
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In silico modeling technologies are transforming drug development and manufacturing by enhancing efficiency, accuracy, to allow innovations.
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A new collaboration helps to remove obstacles from the critical path, reduce development risks, eliminate the white space in pre-clinical drug development, and shorten the pathway to clinical development.