INSIGHTS ON DRUG DEVELOPMENT

• Ask Us Anything: Erik Feldmann On Advancing Peptide Development

  Erik Feldmann, Technical Director, on the analytical challenges of proteins, peptides, and oligonucleotides — and why he starts every method-development problem by understanding what the customer is trying to achieve.

• Developing A Quantitative Surrogate Peptide Assay

  Discover a streamlined LC-MS/MS workflow for Fc-containing therapeutics like dulaglutide to enable precise quantification with LLOQ as low as 1 ng/mL through automated, efficient assay development.

• ITC: Unveiling Its Role And Importance In Drug Design

  Explore how Isothermal Titration Calorimetry empowers drug discovery, as well as learn about ITC fundamentals, how to eliminate weak candidates, and how to optimize development decisions.

• Automation Of 3D Intestinal Organoids Culture

  Gain insight into how 3D organoids promise better disease modeling and drug screening and how challenges like assay complexity, reproducibility, and scalability hinder their widespread adoption in drug discovery.

• Solving Formulation Challenges Across Modalities

  6/15/2026

  Optimize drug delivery by leveraging advanced nanoparticle engineering to dramatically increase small-molecule oral drug loading and enable ultra-high-concentration subcutaneous formulations.

• Chromatography Polishing Under Pressure: New Demands

  9/11/2026

  Upstream productivity gains and evolving antibody formats are raising the bar for chromatography polishing, making it a more consequential variable in downstream process design.

• MAPK Signaling Pathway

  4/7/2025

  Mitogen-activated protein kinase cascades regulate key cellular processes like proliferation, differentiation, and apoptosis. Explore how these pathways maintain cellular homeostasis and contribute to disease development.

• A Timeline Of U.S. Actions To Reduce Animal Models In Research

  6/25/2026

  Policy and scientific validation have aligned to shift drug development beyond animal models. New regulations and technologies are making human‑relevant methods the standard for preclinical research.

• Effect Of Column Chemistry On The Separation Of GLP-1 Peptides

  7/29/2026

  Small changes in mobile phase, temperature, and column chemistry can affect the detection of GLP-1 peptide impurities. Learn which conditions improve resolution for challenging peptide analyses.