INSIGHTS ON DRUG DEVELOPMENT

• Early Development Considerations For Late-Stage NCE Success – Part One

  Navigating NCE development can be daunting. Learn about the importance of assessing and mitigating risk at every stage of development and ensure that your NCE has the maximum potential for success.

• 3D Neurospheres In Healthy And Alzheimer's: iPSC-Derived Neurons

  Explore how different ApoE alleles influence Alzheimer's Disease risk using iPSC-derived neurons as well as gain insights into AD mechanisms and potential therapies.

• Formulation And Analytical Tour

  Take a brief tour of Nanoform’s advanced nanoformulation, nanoanalytical, and best-in-class capabilities.

• Overcoming Obstacles On The Journey To Commercialization

  Explore case studies in the development and manufacturing of APIs and HPAPIs as well as innovative solutions designed to address and overcome challenges in bringing new medicines to patients.

• The Power Couple: CRISPR And Oligonucleotides

  3/4/2024

  Drug design using CRISPR depends on long guide RNA (gRNA) sequences. Find out how this match between long oligos and CRISPR works.

• Bioprocess Optimization: Leveraging Functional DOE With Time-Based Insights

  3/5/2025

  Explore the key differences between traditional DOE and Functional DOE as Seongjin Kim demonstrates how the latter enhances bioprocess optimization through a fed-batch cell culture example.

• Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales

  5/16/2025

  Raman spectroscopy has revolutionized manufacturing through real-time monitoring. Explore a system that enables a seamless calibration model transfer from small- to large-scale bioreactors to enhance scalability and efficiency.

• Topliss Sets In Drug Design Technical Notes For The Medicinal Chemist

  8/3/2023

  When considering new, innovative, and efficient drug design processes, you may want to review Professor J G Topliss's non-mathematical operational schemes for analogue design.

• Preclinical Evaluation Of Vaccines And Antivirals In RSV Challenge Rodent Models

  6/10/2025

  Here, we present multiple case studies utilizing clinically relevant mouse and rat models to evaluate key characteristics of potential RSV therapeutics.