INSIGHTS ON DRUG DEVELOPMENT
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Streamlining Biologics Development: Leveraging Small-Scale Studies For Greater Efficiency
Uncover how a data-driven approach to small-scale studies not only accelerates development timelines but also enhances decision-making and resolves full-scale manufacturing challenges across diverse biologic modalities.
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Label-Free Analysis Of Multiple Spheroids In A Matrix
Gain insight into how automated z-stack imaging and AI-based analysis enable accurate, label-free monitoring of spheroid development in 3D matrices for drug screening and cell culture workflows.
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How Data-Driven Development Is Transforming Phosphoramidites
High-quality phosphoramidites are key to oligonucleotide therapies. Learn how data-driven optimization boosts purity, streamlines manufacturing, speeds scale-up, and supports commercialization.
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Why Reshoring Is An Essential Strategy For ADC Supply Chain Security
Biotechs reshoring their supply chains to Western regions to mitigate risk and improve reliability require experienced partners to effectively manage these complex transitions.
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Advances In Custom Medium Development: The Multi-Omics Difference6/9/2025
Spent media analysis continues to be an essential part of many media development workflows. Newer techniques, however, using state-of-the-art analytical technology, are becoming more popular.
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Aggregate Analysis Of Semaglutide12/11/2025
Effective size exclusion chromatography (SEC) for Semaglutide aggregate analysis is possible without high organic solvents or acidic modifiers. Learn about this robust method for improved efficacy.
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Advancing The Development Of Syringe-Device Combinations10/22/2026
Defining the design for syringe-autoinjector pairings early, through shared compatibility testing, can reduce integration risk for high-viscosity biologics intended for self-administration at home.
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Biologic Stability: A Thermofluor Screen For Rational Buffer Optimization9/23/2025
Learn how thermal shift fluorimetry (thermofluor) can be used as a rapid, low-volume, and cost-effective technique to accelerate buffer optimization and enhance protein stability.
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Why Controlled Release Is Essential For Patient-centric Drug Development10/15/2026
Controlled release design can ease daily dosing burden by moderating swings in drug exposure, though the right approach depends on API properties and what manufacturing can deliver at scale.
DRUG DEVELOPMENT SOLUTIONS
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Emulate's kits provide the essential components needed to create functional, living organ models on the Zoë® Culture Module.
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Calculators & Predictors for LogP, LogD, pKa, Aqueous Solubility, and more…
The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.
ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.
- Predict aqueous solubility,* boiling point, logD,* logP,* pKa,* Sigma, and other molecular descriptors for organic compounds, from structure
- Evaluate the calculated results with sorting, plotting tools
- Assess the reliability of predicted physicochemical property values
- Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
- Train predictors with experimental data to better reflect novel chemical space
- Include custom models and in-house prediction algorithms
*Models are trainable with experimental data
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With high-performance optics and ergonomic design, the Leica DM IL LED is ideal for cell culture, micromanipulation, documentation of immunostained specimens, and routine live cell examinations.
The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient.
For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).
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Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
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Explore chromatography methods for sample preparation, residual solvent, and impurity analysis, critical steps for Active Pharmaceutical Ingredient (API) quality control.