INSIGHTS ON DRUG DEVELOPMENT

• Sustainable Manufacturing Through Automation, Flow Chemistry, And Biocataysis

   Learn how modeling, high-throughput tools, and advanced analytics enable safer, more efficient routes and support scalable solutions for complex chemical and enzymatic processes.

• Spray Dried Dispersions In Controlled Release Formulations

  Integrating spray dried dispersions with CR strategies addresses poor drug solubility and the need for tailored release kinetics. Explore considerations to ensure stability and sustained supersaturation.

• A Study To Assess Organoid Size And Cell Count From 3D Image Analysis

  Recent advancements in 3D patient-derived organoids (PDOs) offer improved predictive power over traditional 2D assays. Explore a patented bioprocess for PDO expansion that could revolutionize drug discovery, especially in oncology.

• Bioprocess Optimization: Leveraging Functional DOE With Time-Based Insights

  Explore the key differences between traditional DOE and Functional DOE as Seongjin Kim demonstrates how the latter enhances bioprocess optimization through a fed-batch cell culture example.

• Simplify Cell Line Development

  11/7/2025

  A streamlined workflow combining microfluidic dispensing and multimodal imaging enables efficient single-cell isolation, viability assessment, and outgrowth analysis to support cell line development.

• Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip

  4/9/2024

  Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.

• Advancing 3D Cell Culture Models For Clinical Relevance

  4/9/2024

  Concerns about in vitro relevance and animal study limits have advanced cell culture tech. Explore how Organ-Chips offer a refined approach to studying human physiology.

• Modeling Colorectal Cancer Progression

  8/2/2024

  Gain a better understanding of the microenvironment's role in colorectal cancer progression by reviewing the integration of Organ-Chip models with high-content imaging and mass spectrometry-based metabolomics.

• Accelerating Clinical Development: Modern Tools In Process Chemistry

  1/23/2025

  Whether you aim to address bottlenecks or explore advanced techniques, gain a practical and forward-thinking perspective to streamline early-phase development with HTE and model-based approaches.