DRUG DEVELOPMENT SOLUTIONS

• Laser Microdissection Microscope - Isolate Single Cells

  LMD 6 Laser Microdissection Microscope

  Dissection Perfection

  Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.

  LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.

  We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.

• Calculate Physicochemical Properties

  Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

  The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

  ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

  • Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
  • Evaluate the calculated results with sorting, plotting tools
  • Assess the reliability of predicted physicochemical property values
  • Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
  • Train predictors with experimental data to better reflect novel chemical space
  • Include custom models and in-house prediction algorithms

  ^*Models are trainable with experimental data

• Fast, Compact Absorbance Microplate Reader For a Wide Range Of Assays

  Filterless readers provide consistent results with steady temperature regulation

  The SpectraMax® ABS and ABS Plus absorbance microplate readers provide the flexibility, sensitivity, and convenience for a wide range of assays such as ELISAs, microbial growth, and protein quantitation. Both readers feature an 8-channel read head for fast reads and a subset feature, the temperature independent PathCheck sensor that automatically normalizes and ensures accurate absorbance values by detecting pipetting errors. Combined with a wide application base, industry-leading SoftMax® Pro Software and validation tools, these readers fit in every lab and every budget.

• In-Silico Modeling Services

  In silico modeling technologies are transforming drug development and manufacturing by enhancing efficiency, accuracy, to allow innovations.

• Integrated Programs To Bridge Molecules From Discovery Into Clinical Development

  A new collaboration helps to remove obstacles from the critical path, reduce development risks, eliminate the white space in pre-clinical drug development, and shorten the pathway to clinical development.

• Columns To Optimize Your GC Analysis
• iCELLis™ Single-Use Fixed-Bed Bioreactor Systems
• Small Is Powerful, Small Is Green
• Gibco Media And Feeds Selection Guide