INSIGHTS ON DRUG DEVELOPMENT

DRUG DEVELOPMENT SOLUTIONS

  • Emulate's kits provide the essential components needed to create functional, living organ models on the Zoë® Culture Module.

  • Calculators & Predictors for LogP, LogD, pKa, Aqueous Solubility, and more…

    The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

    ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

    • Predict aqueous solubility,* boiling point, logD,* logP,* pKa,* Sigma, and other molecular descriptors for organic compounds, from structure
    • Evaluate the calculated results with sorting, plotting tools
    • Assess the reliability of predicted physicochemical property values
    • Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
    • Train predictors with experimental data to better reflect novel chemical space
    • Include custom models and in-house prediction algorithms

    *Models are trainable with experimental data

  • With high-performance optics and ergonomic design, the Leica DM IL LED is ideal for cell culture, micromanipulation, documentation of immunostained specimens, and routine live cell examinations.

    The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient.

    For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).

  • Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.

  • Explore chromatography methods for sample preparation, residual solvent, and impurity analysis, critical steps for Active Pharmaceutical Ingredient (API) quality control.