INSIGHTS ON DRUG DEVELOPMENT

• Is Lipinski's Rule Of Five Still Relevant In Drug Development?

  Some drugs violate multiple Ro5 elements but remain developable, while some molecules adhere strictly to the Ro5, but their properties are not conducive to development.

• Formulation Development Of Enterically Protected Spray Dried Dispersions

  Adrulipase spray-dried dispersions were evaluated to create an orally delivered, enteric-protected enzyme. The lead formulation provided the best acid protection, rapid release, and stability.

• Why Pharmaceutical Scientists Trust The Discovery Core Rheometer

  Drug formulations demand more than single‑point viscosity data. Explore how rheology reveals stability, flow, and structural behavior across suspensions, topicals, and injectables.

• Characterizing Protein Stability By DSC

  Discover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.

• The Role Of A Consulting Firm In The IND Process

  6/10/2025

  Navigate the complex IND process with expert guidance and discover how early FDA engagement can accelerate your path to clinical trials.

• Studying The Spatial Architecture Of Glioblastoma

  3/24/2025

  Explore how intra-tumor heterogeneity (ITH) impacts cancer progression and therapy resistance with advanced imaging platforms and custom antibody panels to reveal the spatial architecture of glioblastoma (GBM).

• Advancing GLP-1 Analog Drug Development Using A Variety Of Techniques

  6/27/2025

  Discover how SEC-MALS reveals the aggregation behavior of GLP-1 analogs like semaglutide and liraglutide, which are critical for ensuring the stability, efficacy, and safety of peptide therapeutics.

• Cell Culture Automation Of The 3D Cancer Spheroid Assay

  3/24/2025

  Discover how automated 3D cell culture methods enhance efficiency and consistency in high-throughput drug screening to accelerate the discovery of new anti-cancer therapies.

• VEGF Signaling Pathway

  3/24/2025

  In Alzheimer's disease, reduced VEGF levels are linked to neurodegeneration, which can offer therapeutic potential. Discover how experimental treatments show promise in reducing memory impairment and beta-amyloid deposition.