INSIGHTS ON DRUG DEVELOPMENT

• Isolate Bright GFP-Expressing HEK293 Cells For Cell Line Development Workflow

  Explore a high-efficiency workflow for isolating and expanding GFP-expressing HEK293 cells that enables stable, bright clones ideal for imaging and tracking to simplify clonal development.

• Aggregation In Antibody-Drug Conjugates: Causes And Mitigation

  Discover how early intervention in ADC development can streamline clinical progress, ensure stability and safety, and accelerate commercialization with expert guidance.

• Improving API Solubility With Mesoporous Silica

  Poor solubility of active pharmaceutical ingredients can hinder drug effectiveness. Learn how innovative formulation strategies enhance solubility and bioavailability to improve therapeutic outcomes for challenging drug candidates.

• Recapitulating Inflammation: How To Use the Colon Intestine-Chip To Study Complex Mechanisms Of IBD

  To address the challenges associated with conventional drug development models, a Colon Intestine-Chip has been developed to recapitulate the biology that drives inflammatory bowel disease.

• Understanding Biotherapeutic Peptides And GLP-1 Receptor Agonists

  9/2/2025

  Biotherapeutic peptides offer enhanced safety and efficacy over traditional drugs. Learn why rigorous impurity profiling is vital to ensure product quality, patient safety, and regulatory compliance.

• The Role Of Peptones In Boosting Quality And Yield

  11/4/2024

  Peptones can significantly boost CHO cell bioprocessing. We analyze their impact on diverse CHO cell lines using real-world data to assess their effects on titer, protein quality, and cell growth.

• Bioprocess Optimization: Leveraging Functional DOE With Time-Based Insights

  3/5/2025

  Explore the key differences between traditional DOE and Functional DOE as Seongjin Kim demonstrates how the latter enhances bioprocess optimization through a fed-batch cell culture example.

• Tablet Edge Erosion – Solutions For Friability

  11/11/2024

  Addressing tablet edge erosion and friability involves adjusting formulation, tablet design, tooling, press setup, and operation speed to improve tablet robustness and reduce weight loss.

• A New Framework For Identifying Nitrosamine Risks And Derisking Products

  6/18/2024

  Examine a new methodology that holds significant promise for identifying APIs at risk for NDSRI formation, enabling manufacturers to prioritize risk mitigation strategies and ensure compliance.