Utilization Of A Novel Rotor-Granulator Powder Layering Technique To Taste Mask Acetaminophen Pellets With EUDRAGIT® E PO

January 5, 2010

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•Poster: Utilization Of A Novel Rotor-Granulator Powder Layering Technique To Taste Mask Acetaminophen Pellets With EUDRAGIT® E PO

By Evonik Röhm GmbH

EUDRAGIT® E PO is a polymer commonly used for the taste masking of bitter drugs. The polymer can be applied from an organic system using a volatile solvent or formulated as a colloidal solution as an aqueous-based system. A new technology, recently developed by Vector Corporation, has used filmforming polymers to coat dosage forms via a powder layering technique.

The purpose of this study was to investigate the taste masking of acetaminophen beads with EUDRAGIT® E PO powder utilizing a novel, low temperature rotor-granulator process.

Click Here To Download:
•Poster: Utilization Of A Novel Rotor-Granulator Powder Layering Technique To Taste Mask Acetaminophen Pellets With EUDRAGIT® E PO