Biopharma Services Brochure

Using an array of analytical techniques we are able to characterise formulations in terms of thermal properties (softening events, molecular mobility) as well as specific lyophilisation-related parameters such as the collapse temperature (Tc), which is the critical upper temperature limit for successful freeze-drying of almost all formulations. We can also determine some of the more “qualitative” characteristics of a formulation that have traditionally been difficult to analyse, such as crust formation and crystal growth. Therefore, we are able to carry out formulation development work on a rational, scientific basis.