Application Note: Cough Suppressant Expectorant

We used a Brookfield RVDV-III+ Rheometer, with Rheocalc v3.1 software for automated instrument control and data acquisition. The temperature was regulated using an ULA-EY water jacket connected to a TC-502P Refrigerated Programmable Bath. We ran three trials to determine repeatability. A syringe was used to measure and dispense 16 mL of the substance into the sample chamber. The spindle and chamber were cleaned before each trial, and fresh material was used in each trial. We equilibrated the sample, spindle and chamber for at least three minutes prior to testing. We ran our test in a speed ramp fashion. Using traditional RV speeds like 50 and 100 rpm can make a sufficient test for this type of material. However, since we used a DV-III+ Rheometer we had the capability of running the test at a wide variety of speeds.