AstraZeneca / IBC High Containment Discharge Station With CIP

After extensive evaluation and testing, AstraZeneca selected the Matcon "Cone Valve" Intermediate Bulk Container system to handle the storage, movement and transfer of production batches across each step in the manufacturing process.

The manufacturing process contains the following steps:

• Dispensing into IBCs using high containment barrier isolation technology;
  
• Granulation and Fluid Bed Drying – IBCs provide contained transfer into process;
  
• Milling – IBCs provide controlled feed to milling process;
  
• IBC Blending, incorporating NIR PAT for blend uniformity;
  
• Tablet Compression – IBCs provide mass-flow into tablet presses;
  
• Tablet Coating and Packaging – tablets are moved in bulk by IBCs and fed to process;