Headspace Measurement Services

Headspace measurement services are carried out by LIGHTHOUSE laboratory facilities in Charlottesville, Virginia and Amsterdam, The Netherlands. Clients requiring rapid non-destructive headspace analysis can choose from several service options. Samples can be sent to LIGHTHOUSE for analysis, equipment can be brought to the client and analysis performed on site by LIGHTHOUSE Application Scientists, or equipment can be implemented at the client on a project basis for a short term lease. Headspace systems from LIGHTHOUSE utilize a patented laser absorption technique developed with funding from the Food and Drug Administration and have been implemented & validated by the industry for more than a decade. Measurement Services clients take advantage of the expertise at LIGHTHOUSE gained from analyzing millions of samples from sterile drug facilities all over the world to address the following applications:

Applications include:

• Container closure integrity inspection and leak rate modeling
• Headspace oxygen stability studies
• Nitrogen purge optimization & validation
• Lyo chamber moisture mapping
• Lyo cycle optimization
• Packaging permeation studies