Newsletter | March 12, 2024

03.12.24 -- Leveraging Taste Masking And Enhancement To Ensure Compliance In Children

Formulation Considerations For Pediatric Populations

For pediatric populations, medication adherence can be complicated by considerations such as a child’s ability or willingness to accommodate any bitterness or texture issues. By partnering with a CDMO with experience in pediatric formulation, pharmaceutical companies can increase acceptability of their drugs among pediatric patients.

 

Challenges With Pediatric Flavors For Taste Enhancement And Modulation

A medication’s taste is a critical component of patient compliance in children, but taste masking for children can present unique challenges. This webinar discusses how we can use flavor, not just to provide a desired taste, but also to provide taste masking. Take a deep dive into taste perception and the origin of most taste ingredients.

 

Masking Bitter Drug Taste In Pediatric Formulations With Microcaps

A sponsor was developing a taste-masked, convenient dosage formulation of a very bitter API for patients two-years-old and older undergoing treatment of HIV infection. Learn how a powder formulation was used to overcome barriers such as at-home administration, sub-optimal storage conditions, and flexible dose requirements.

 

Partnering With Clinicians To Improve Pediatric Formulation Development

Review the proposed use of a pediatric quality target product profile as an efficient tool to facilitate early planning and decision making during children-centric formulation design. Greater collaboration between formulation experts and clinical colleagues is advocated to ensure safe, effective, and age-appropriate medicinal products.

 

Taste-Masking Solutions For Pediatric Populations

Originally introduced by Srinivasan Shanmugam, senior director pharmaceutical sciences, Adare Pharma Solutions, this presentation reviews the pediatric population and their needs concerning safe, efficacious dosing, the significance of taste masking in improving medication adherence, and taste-masking strategies.