Marken Cold-Chain Management Information Sheet

Marken is one of the leading suppliers of cold-chain logistics of clinical supplies worldwide. Temperature-control during the handling, storage and distribution of cold-chain products is a critical element of the clinical trial process. Failure to remain within temperature range compliance can seriously disturb the running of the clinical trial. Distribution of investigational drug, vaccines and other clinical trial materials often requires very specific temperature control to maintain the stability of the product.

Temperature excursions of cold-chain clinical trial materials (CTMs) and investigational medicinal products (IMPs) can significantly alter its efficacy and use in the trial. With many clinical specimens required to be frozen at -78.5 degrees Celsius or maintained at refrigerated temperatures between 2 - 8 degrees Celsius, temperature variations of a few degrees can affect the integrity of the specimens. Expertise in cold chain logistics of clinical products is of critical importance to ensuring the safe arrival of high value trial medication to sites.