Pharmaceutical Nanotechnology Formulation

Drug particles in the nanometer size range have unique characteristics that can lead to enhanced performance in a variety of dosage forms. Formulated correctly, particles in this size range are resistant to settling and can have higher saturation solubility, rapid dissolution, and enhanced adhesion to biological surfaces, thereby providing a rapid onset of therapeutic action and improved bioavailability. Scientists at Cirrus Pharmaceuticals, Inc. use nanotechnology to approach classical and novel drug delivery applications. We provide services for producing, formulating, and characterizing nanoparticles for a wide array of applications including, but not limited to, oral, pulmonary and parenteral delivery.

Applications

Oral

• Improving solubility and bioavailability of poorly soluble drugs
• Reducing fed / fasted variability
• Reducing inter-subject variability
• Drug targeting

• Novel formulation opportunities

• Potential for intravenous administration of poorly soluble drugs
• Activity screening of newly developed poorly soluble drugs
• Drug targeting