Natoli Engineering Company, Inc., is the recognized global leader in tablet press tooling manufacturing. Founded on the uncompromising principle to manufacture and deliver only the highest quality tablet compression tooling, presses and replacement parts at a fair price with exceptional customer service, Natoli has been at the forefront of the tablet compression industry for over 40 years. Our state-of-the-art manufacturing facilities, award-winning engineering team and dedicated production crew enables us to offer clients competitive pricing without compromising our high standards of customer service. Trust in Natoli – our staff has the industry knowledge and expertise to understand and meet your exact requirements and requests.

We’re the one-stop shop in tablet compression tooling

It’s well known that Natoli manufactures punches and dies of unparalleled quality, but we also provide all the technical knowledge and support equipment that you need to maintain tablet quality. In addition to high-quality tablet tooling, we manufacture:

  • Tablet presses
  • Replacement Turrets
  • Feeder assemblies, covers and paddles
  • Cam Tracks
  • Compression Rollers
  • A comprehensive accessories catalog solely dedicated to the tablet compression industry

Replacement parts and turrets for nearly all makes and models of tablet presses, totaling more than 250,000 in stock, with most being available of shipping same day.

Tooling for all segments

Natoli is proud to service the pharmaceutical, nutraceutical, confectionary and industrial segments in the tablet compression industry. Our knowledge and expertise in steel and coating types and qualities, and customer support and troubleshooting are what differentiates us from our competitors. This expertise provides our customers with innovative products and options not offered elsewhere in the market.

Natoli is committed to research and development

Our commitment to the tablet compression industry means we continuously strive to develop groundbreaking solutions and improvements in our own manufacturing processes and for the entire tableting industry.

Our dedication to innovation and excellence has earned us an international reputation for high quality and reliability. We are strong believers when it comes to investing in the industry’s future, particularly research and development. Our Scientific and Metallurgy divisions provide professional scientific testing and analysis that helps the industry find solutions to the pervasive issues we all face.

Some of the issues Natoli Scientific can help evaluate include:

  • Formulation for Sticking Problems
  • Formulation for Tool Steel and Coating Recommendation
  • Formulation Modification to Improve Tableting and Performance in the Tablet Press
  • Recommendations on Coatings for Abrasive and Corrosive Formulations

Natoli Metallurgy can also assist with issues including:

  • Selection and treatment of steels to improve the longevity of your tooling
  • Analysis of material chemistry and coatings
  • Troubleshoot tool failure in tool steels and stainless steels
  • Conduct wear testing on metal components of your tablet presses or other machines

Natoli’s headquarters is strategically located in one of the Midwest’s finest progressive industrial parks where our 120,000-sq ft campus includes administrative, manufacturing, refurbishing, training and clean room facilities specifically designated for product demonstration and testing. Whatever your tablet tooling needs, choose the experience and dependability of Natoli Engineering Company, Inc. to provide the right solution.

Whatever your tablet tooling needs, choose the experience and dependability of Natoli Engineering Company, Inc. to provide the right solution.


You Demand. We Deliver.




Natoli Engineering Company, Inc.

28 Research Park Circle

St. Charles, MO 63304


Phone: 636-926-8900

Fax: 636-926-8910

Contact: Dale Natoli