Products and Services
Sustained-Release Formulations
Source:
Evonik Röhm GmbH
Sustained-release EUDRAGIT® formulations are employed for many oral dosage forms to enable time-controlled release of active ingredients. Drug delivery can be controlled throughout the whole gastro-intestinal tract for increased therapeutic effect and patient compliance.
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•Datasheet: Sustained-Release Formulations
•Datasheet: Sustained-Release Formulations
•Datasheet: Sustained-Release Formulations
Sustained-release EUDRAGIT® formulations are employed for many oral dosage forms to enable time-controlled release of active ingredients. Drug delivery can be controlled throughout the whole gastro-intestinal tract for increased therapeutic effect and patient compliance. Different polymer combinations of EUDRAGIT® RL and RS grades allowing custom-tailored release profiles enable a wide range of alternatives to achieve the desired drug delivery performance.The EUDRAGIT® NE polymer is a neutral ester dispersion which requires no plasticizer and is particularly suitable for granulation processes in the manufacture of matrix tablets and sustained release coatings.
There are two formulation options:
- EUDRAGIT® is employed as a coating material,usually for the coating of pellets or particles that are filled into capsules or compressed into tablets. These pellets or particles act as diffusion cells in the digestive tract and release a constant drug quantity per unit of time (multi-unitdosage forms).
- EUDRAGIT® serves as a matrix by which the active ingredient is embedded. The matrix structure is obtained by direct compression,granulation, or melt techniques.
•Datasheet: Sustained-Release Formulations
