WHITE PAPERS & CASE STUDIES
A Mesoporous Silica Carrier Optimized For Liquisolid And Lipid-Based Formulations
Syloid® XDP silicas are mesoporous, amorphous, silica gel excipients with a unique morphology that create an excellent solid porous carrier for pharmaceutical formulations. The combined adsorption capacity, porosity, particle size, and density provides a tool to create formulations which can expedite manufacturing and improve efficacy of the final dosage form.
Enhancing Stability In Nutraceutical Products
Nutraceuticals are natural products that are used to provide medical or physiological benefits.
Is "Yield Stress" As Important As "Viscosity?"
“Yield Stress” could be a term that applies to our daily lives. When under pressure, if the stress is too great, you start to “change” in a figurative sense. In the world of science and engineering, fluids and semi-solid materials that are subjected to a strong-enough force will start to move. Basically they “change” from their original shape and move in response to the applied force, remaining in motion as long as the force is great enough.
Viscosity Flow Curve Tells All
Characterizing any material for flow behavior involves testing it over a range of shear rates relevant to how it is processed in manufacturing or how it is used by the consumer. Ointments, for example, are used to coat human body parts like skin, lips, finger/toe nails, hair, eyeballs, etc. The coating action is such that the medicinal mixture, once applied to the surface of the object, spreads as it is rubbed into place. Therefore, a relevant viscosity test would employ shear rates that mimic this type of spreading action.
Challenges & Opportunities: Encapsulation Of Liquid & Semi-Solid Formulations Into Oral Capsules
The encapsulation of liquids and semi-solids provides solutions for convenient delivery through improved oral absorption of poorly water-soluble drugs.
Replacing Activated Carbon With Zeta Plus™ Activated Carbon Depth Filter Cartridges In Pharmaceutical Applications
Activated carbon is widely used in the pharmaceutical industry to remove a range of soluble impurities from process streams containing active pharmaceutical ingredients (APIs). The structural characteristics of activated carbon make it ideal for removing impurities such as chromophores and homogeneous metal catalysts. It is generally reliable and economical for traditional pharmaceutical manufacturing operations.