Medicago’s Innovative Vaccine Production Using Tobacco Plants
In the American South, below the old Mason-Dixon Line, you can walk down some house-lined streets in summer and see tidy plantings of tobacco growing in the front yards. Tobacco barns, built for drying, not storing, are as common down there as hay barns in Wisconsin.
WHITE PAPERS & CASE STUDIES
Single-Use Technology: The Trust Factor
What is missing today is trust. The axiom “trust but verify” is truer with single-use systems than in the past. The customer/supplier relationship required with single-use systems cannot be transactional, but must be a long term partnership for mutual success. This has to be built on a foundation of trust, and that is lacking today. For the end users, the implementation of single-use systems represents an outsourcing of critical operations, previously performed and controlled by their own people and quality management system.
A Mesoporous Silica Carrier Optimized For Liquisolid And Lipid-Based Formulations
Syloid® XDP silicas are mesoporous, amorphous, silica gel excipients with a unique morphology that create an excellent solid porous carrier for pharmaceutical formulations. The combined adsorption capacity, porosity, particle size, and density provides a tool to create formulations which can expedite manufacturing and improve efficacy of the final dosage form.
Challenges & Opportunities: Encapsulation Of Liquid & Semi-Solid Formulations Into Oral Capsules
The encapsulation of liquids and semi-solids provides solutions for convenient delivery through improved oral absorption of poorly water-soluble drugs.
Automated pH Adjustment In An Intelligent Single-Use Mixing Platform
Most pH adjustment process steps in single-use biomanufacturing require manual manipulation of the product and vessel, including off-line sampling, pH measurement, and the addition of acid and base.
Sterile Manufacturing – Current Trends And Developments
The pharmaceutical industry is currently in a state of flux. The introduction of classic blockbusters is diminishing. At the same time, biotechnology is just beginning to discover its potential.
AMRI Aseptic Manufacturing Case Studies
AMRI has expertise with formulating and filling small and large molecules, proteins, liposomes, emulsions, suspensions, nanoparticle dispersions (e.g. liposomes), viscous gels, biopolymers, synthetic polymers, potent/cytotoxic material and controlled substance.