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FEATURED ARTICLES

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WHITE PAPERS & CASE STUDIES

  • Customizing A Capsule Filling Line For Immunosuppressant Drugs
    Customizing A Capsule Filling Line For Immunosuppressant Drugs

    To secure their position in an increasingly fierce market environment, pharmaceutical companies keep pushing the boundaries of their production capacities. Reaching that goal not only requires them to increase batch sizes. They must also optimize their existing manufacturing processes with state-of-the-art equipment and software systems while ensuring maximum safety for both products and operators. This is exactly what Bosch Packaging Technology offers its customers with tailor-made capsule filling lines backed by decades of experience in capsule filling processes and technology.

  • Closed System Filling Technology: A New Paradigm
    Closed System Filling Technology: A New Paradigm

    “Closed system filling” is a new set of processing controls appropriate for a sterile filling process that eliminates potential microbiological contamination from environmental and operator sources through the use of closed systems. This is an automated sterile connector technology by which presterilized closed containers are filled through an engineered and controlled passage enabling the filled product, the internal container and the closure system surfaces to avoid exposure to the background environment.

  • How Broadening The Analysis Of Compound Factors Allows For Predictive Solubility Solutions
    How Broadening The Analysis Of Compound Factors Allows For Predictive Solubility Solutions

    The Biopharmaceutics Classification System (BCS), developed by the U.S. Food and Drug Administration to simplify and accelerate the drug development process, helps companies when they file for bioequivalence of dosage forms based on in vitro dissolution testing. The objective of the BCS system is to predict in vivo performance of drugs from in vitro measurements of solubility and permeability. The system has evolved to classify low-soluble drugs according to their permeability (BCS Class II or IV). A compound’s classification (I through IV) is indicative of its potential bioavailability.

  • Takeda Upgrades Pharmaceutical Tablet Coaters With Minimum Downtime
    Takeda Upgrades Pharmaceutical Tablet Coaters With Minimum Downtime

    In order to keep up with fast developing technical standards, pharmaceutical manufacturers face the question whether investing in new equipment is the most profitable solution.

  • Achieving Results With Sterilization Training For Complex Production Processes
    Achieving Results With Sterilization Training For Complex Production Processes

    Training courses provided by the Bosch Packaging Academy support Alcon employees to ramp up expertise for SDR sterilizers.

  • How A Placebo Formulation Is Designed For An Oral Solid Dose Product
    How A Placebo Formulation Is Designed For An Oral Solid Dose Product

    To demonstrate the process by which a placebo formulation was designed for an oral solid dose product that would be dispensed to the patient as a fast-dissolve tablet.  The tablet is added to water and the resulting solution is dosed as a antibiotic mouthwash.   Placebo matching was required not only for the tablet but also for the solution which the patient took.

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PRODUCTS & SERVICES

NDA Approval And Post Approval Services NDA Approval And Post Approval Services

From 2006 through 2015, Patheon helped clients earn 92 NDA approvals. That’s  twice as many as any other CMO. Success brings more success at this stage. That’s because depth of experience, reliability of quality and refinement of processes are all important in the final push for regulatory approval and making the transition to commercial manufacturing.

Small Molecule Development And Manufacturing Services Small Molecule Development And Manufacturing Services

High-quality API via the development of a scalable process that will meet demand at each stage of your product’s life cycle. Complete drug product services from preformulation screening through clinical development to commercial supply. A comprehensive range of oral solid, sterile and softgel dosage forms with expertise in high-potency products. Unique solutions to overcome the toughest solubility challenges and accelerate your path to proof of concept.

Drug Product Development Services Drug Product Development Services

Considering that 90% of drug candidates have bioavailability issues, making sure your program is prepared for all phases of clinical trials from the very start is the fast way forward. Patheon Solubility Enhancement Services approaches BCS II and IV drug substance solubility issues a fundamentally different way that identifies the solubility enhancement technologies most likely to work before you get started. That helps eliminate rework and worry later on.

Compounding Pharmacy Isolator Compounding Pharmacy Isolator
The PharmaGard ES PR797 Compounding Pharmacy Isolator creates a recirculating positive pressure ISO Class 5 clean air controlled environment for aseptic compounding of non-hazardous drugs guaranteed to meet your USP 797 compliance requirements.
Pharmaceutical Compounding Aseptic Containment Isolator Pharmaceutical Compounding Aseptic Containment Isolator

The PharmaGard ES NR797 Compounding Containment Pharmacy Isolator creates negative pressure recirculating ISO Class 5 clean air environment for aseptic compounding of hazardous drugs and minute quantities of chemotherapy drugs to meet USP 797 requirements.

Pharmaceutical Steam Sterilizer: FOB-TS Pharmaceutical Steam Sterilizer: FOB-TS

L in FOB-TS series combines outstanding performance with high quality materials, ease of use and reduced consumption.

Pharmaceutical Vertical Laboratory Sterilizer: FVG Pharmaceutical Vertical Laboratory Sterilizer: FVG

L in FVG series combines outstanding performance with high quality materials, ease of use and reduced consumption.

Pharmaceutical Laboratory Sterilizer: FVS Pharmaceutical Laboratory Sterilizer: FVS

L to FVS series combines outstanding performance with high quality materials, ease of use and reduced consumption.

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