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  • Pharmaceutical Powder Flow Characterization: Small Volume Testing Needed
    Pharmaceutical Powder Flow Characterization: Small Volume Testing Needed

    There is a saying: Go big or go home. But not when dealing with sample testing of pharmaceutical powders. Then the saying is: Waste not, want not. In the cutthroat world of Big Pharma, staying one step ahead of the competition is imperative. Research to create the next new drug is a costly endeavor. Once a new product is developed, speed to market is the next challenge.

  • Water For Injection Measurements

    Water is one of the most widely used raw materials in the pharmaceutical plant. Several grades of water are used throughout the plant. One grade, Water for Injection (WFI), is water purified by reverse osmosis or distillation as specified by the United States Pharmacopeia (USP). Specific tests for Conductivity apply to WFI Water produced on site for manufacturing purposes.

  • Tighter pH Control In Chromatography & Purification Systems

    Biopharmaceutical Chromatography Systems are designed for separating and purifying proteins and bio-engineered products. The systems must maintain a hygienic design. Wetted surface finish must be < 20 μinch Ra and material traceability is important to maintain system integrity. pH measurement plays an important role in the purification process, providing feedback control of buffer and effluent feed through the column. The system’s wetted components must withstand Cleaned in Place (CIP) and Steamed in Place (SIP) cycles, which can stress a sensor with high heat and caustic. The pH sensor must be able to make accurate and stable pH measurements after the cleaning cycles.

  • Tighter pH Control In Biopharmaceutical Application

    In fermentation and cell culture, one of the most critical process challenges is to maintain the optimal pH level. Fermentation process utilizes a living organism such as a yeast, bacteria, or fungus strain to produce an active ingredient. Fermentation process is normally shorter in duration (2-7 days). Cell culture is a process in which a mammalian cell is grown to produce the active ingredient. The cell culture process is typically longer (2-8 weeks).

  • Tighter Conductivity Control In Chromatography & Purification Systems

    Conductivity measurement plays an important role in the purification process. Conductivity is one of the determinants of when to start and when to end the collection process. Tighter conductivity controls will increase purity yields. In addition, it may improve secondary collection processing.

  • Introduction To Solvent Evaporation
    Introduction To Solvent Evaporation

    Solvent removal is an essential process for sample preparation across a range of applications in many industries. Many sample formats and solvents are used with no single technique providing a universal solution, but despite the variety of specifics evaporation is well-understood and relatively uncomplicated. But while evaporation is an intrinsic step in so many applications it’s rare to find an evaporation expert in a laboratory, and many facilities use systems that are slow and cumbersome simply because they have always been used.

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PRODUCTS & SERVICES

Gas Displacement Pycnometry System: Accupyc II Gas Displacement Pycnometry System: Accupyc II

Gas pycnometry is recognized as one of the most reliable techniques for obtaining true, absolute, skeletal, and apparent volume and density. The AccuPyc II 1340 Series Pycnometers are fast, fully automatic pycnometers that provide high-speed, high-precision volume measurements and true density calculations on a wide variety of powders, solids, and slurries. The instrument completes most sample analyses in less than three minutes without sacrificing accuracy. After analyses are started with a few keystrokes, data are collected, calculations are performed, and results displayed. A minimal amount of operator attention is required.

Envelope Density Analyzer: GeoPyc® 1365 Envelope Density Analyzer: GeoPyc® 1365

The GeoPyc employs a unique displacement measurement technique that uses Dry Flo, a quasi-fluid composed of small, rigid spheres having a high degree of flow-ability. The sample is placed in a bed of Dry Flo which is agitated and gently consolidated about the sample. The GeoPyc collects the displacement data, performs the calculations, and displays or prints the results. The unit also reports percentage porosity and specific pore volume when absolute density information (density excluding pore and small cavity volume obtained from a Micromeritics AccuPyc II pycnometer) is entered.

Single-lane Blistering, Cartoning, And Serialization Machine: BEC 300 Single-lane Blistering, Cartoning, And Serialization Machine: BEC 300

The BEC 300, manufactured by Uhlmann, is the eighth and newest blister line at Ropack Pharma Solutions. The single-lane unit integrates blistering, cartoning and serialization.

Smart Wireless THUM™ Analyzer Advanced Diagnostics Smart Wireless THUM™ Analyzer Advanced Diagnostics

The Smart Wireless THUM Adapter is an easy way to unleash otherwise “stranded” advanced diagnostics, such as pH slope, reference offset, glass impedance, and reference impedance to enable you to diagnose probe condition.

Advanced Dual-Input Analyzer With Continuous Measurements Advanced Dual-Input Analyzer With Continuous Measurements

The Model 56 advanced dual-input analyzer supports continuous measurement of one or two sensor inputs. The modular design allows signal input boards to be field replaced, making configuration changes easy. The high resolution full-color display gives unsurpassed visibility and functionality for liquid analytical instrumentation.

Aerosol Microleak Detection System Aerosol Microleak Detection System

Emerson's Cascade Technologies is the global leader of packaging leak detection systems for the Aerosol, Food, and Pharmaceutical industries. The Cascade CT2211 aerosol microleak detection system is the first Quantum Cascade Laser (QCL) system developed for automated, in-line leak detection.

Dual-Input Intelligent Analyzer Instrument Dual-Input Intelligent Analyzer Instrument

Sensor input with an unrestricted choice of dual measurements. This multi-parameter instrument offers a wide range of measurement choices supporting most industrial, commercial, and municipal applications. The modular design allows signal input boards to be field replaced making configuration changes easy. Conveniently, live process values are always displayed during programming and calibration routines.

Conductivity Sensors Conductivity Sensors

The 140 series sensors are available with a range of cell constants, allowing optimum matching of the sensor to the expected conductivity. For low conductivity, choose the 142 sensor (available with either 0.01 or 0.1 / cm cell constants). For moderately high conductivity choose either the 140 or 141 sensors (both available with 0.2 or 1.0 / cm cell constants). The cell constant is accurate to within ±5 % of the nominal value, so the error in the measured conductivity will be at least ±5 %. For higher accuracy, the sensor must be calibrated by the user. A broad range of calibration standards is available.

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