Today, the trend with vaccine packaging is ready-to-administer single-dose packaging. Whether in the form of prefilled syringes or single-dose twist-off containers, this type of packaging offers safety, convenience, and cost benefits over traditional multidose vials.
Pharmaceutical producers naturally want to utilize their machine capacities to the fullest in day-to-day business. The key words read efficiency, reliability and flexibility – all in line with the highest safety and cGMP standards. Modern and flexible equipment plays a major role in achieving maximum uptime and high quality in all packaging processes. “We always bear in mind our customer’s demands when developing new equipment or designing tailor-made line concepts. This is why all our machines and components are based on a modular concept,” Ralph Pfister, area sales manager at Bosch Packaging Technology, underlines.
Specializing in sterile manufacturing, Excelvision, based in Annonay, France, provides contract manufacturing services for liquid eye drop plastic vials to numerous companies. However, to increase production and capitalize on additional contract manufacturing opportunities, Excelvision enlised Bosch Packaging Systems AG, based in Beringen, Switzerland, to install a fully automated packaging line. With significantly higher output capabilities, Excelvision expects to increase production by nearly five-fold. The new line also gives the company greater flexibility to meet the diverse requirements of its customers.
Shelf life is the length of time that foods, beverages, pharmaceutical drugs, chemicals, and many other perishable items are given before they are considered unsuitable for sale, use, or consumption.
Shelf life studies are used to determine how long a product can reasonably be expected to maintain its quality, safety, and character. These studies take into account not only products’ functional qualities such as safety and effectiveness, but also cosmetic qualities such as color and texture that make them appealing to customers.
Which parameters must pharmaceutical manufacturers take into account for scale-up? How can Quality by Design be introduced in the development phase?
Compact and flexible – these are the dominating keywords when it comes to machines for producing and developing parenterals in small batches. If the machine is also supposed to fill pharmaceuticals into different types of packaging, the market does not have that much to offer. This is why the Fraunhofer ITEM and Bosch Packaging Technology developed the filling and closing machine ARF 1010, which is now in operation at Fraunhofer ITEM’s Pharmaceutical Biotechnology Division in Braunschweig, Germany.