FEATURED ARTICLES

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  Does The Ointment Hurt?

  Patients are quick to complain when a medical ointment stings after application. But there may be another reason that they might be dissatisfied with the way an ointment behaves when it is too thick. By Bob McGregor, General Manager, Brookfield Engineering

• New Blade Design Gives Double Planetary Mixer An Edge With Viscous Applications
• Seamlessly Upgrade Your Mixing Operation

WHITE PAPERS & CASE STUDIES

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  QC Testing: Quality Control Methods That Make A Difference

  By Robert McGregor, Global Marketing and High End Product Manager, Brookfield Engineering Laboratories, Inc.

  How do you bring consistency to QC testing? Pharmaceutical products that meet manufacturability criteria and provide high level consumer satisfaction undergo a battery of tests before being distributed to the consumer. Using affordable instrumentation to perform QC tests, which certify that tablets, capsules, elixirs, ointments, etc. have the right physical properties, is essential for today’s successful business.

• How To Benchmark Powder Flow Behavior

  Unfortunately, there are many variables that affect a powder’s formulation. Consequently, the flow behavior cannot be guaranteed from formulation alone.

• Challenges & Opportunities: Encapsulation Of Liquid & Semi-Solid Formulations Into Oral Capsules

  The encapsulation of liquids and semi-solids provides solutions for convenient delivery through improved oral absorption of poorly water-soluble drugs.

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  Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System

  Formulation scientists have become pivotal to pharmaceutical development, in that they are often faced with the daunting challenge of not only identifying the most suitable drug delivery platform among a myriad of options, but also developing and validating robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames. By Eduardo Jule, Ph.D., Senior Manager, Formulation and Pharmaceutical Development

• Solutions To Batch Mixing Issues

  This white paper presents some strategies for improving commonly encountered batch mixing problems. Because mixing processes vary from one application to another – with different objectives, design configurations, rheologies, operating limitations, etc. – there are no fix-all solutions that will apply to every situation.

• Raising Expectations Of Excipients

  An excipient’s role has traditionally been viewed as merely a filler or binder contributing to the stability of the end product. The full value that a formulation can bring to a final dosage form; or the real importance of ensuring an excipient’s quality and performance; are often underestimated, overlooked, misunderstood, or disregarded. In reality, the functionality of the excipient can help determine whether or not a drug succeeds or fails. By Fred Monsuur, Julia Poncher W. R. Grace & Co

PRODUCTS & SERVICES

Contract Packaging Of Tablets & Capsules

Aphena's Solid Dose Division provides a full range of solid, semisolid and powder packaging solutions backed by dedicated customer service, robust quality and continuous improvement programs, project management and an in-house validation program.

Leak Testing Machine For Filled Bottles

The Leak Testing Machine for filled bottles is used for in-line Non-Destructive Container Closure Integrity Testing.

Pharmaceutical Containment Valves For Aseptic Technologies

Containment valve technology is a widely adopted method of containing the transfer of powder, granular or semi-solid materials from process to process.

In-line Leak Testing Machine for Stick Packs: SQZ

The Leak Testing Machine is used for in-line Non-Destructive Form/fill/seal Stick Pack Closure Integrity Testing. It uses the Force Decay Measurement Method which is accomplished respectively by Container lanes smooth-pressing and successive position level acquisition.

High Speed Pharmaceutical Leak Testing Machine

Thishigh speed leak testing is used for in-line Non-Destructive Container Closure Integrity Testing.

Lid Deflection Leak Testing For Pharmaceuticals

The Measurement System is based on the detection of the Container flexible lidding material displacement, induced by the Vacuum generation into a Testing Chamber.

Non-Destructive In-Line Leak Tester For Vials

The Vial Leak Testing Machine is used for in-line Non-Destructive Container Closure Integrity Testing.

Clinical Manufacturing Services

Kemwell offers clinical manufacturing from lab-scale to commercial, in a wide range of pharmaceutical drug product dosage forms for both small molecule and large molecule.