• Does The Ointment Hurt?
    Does The Ointment Hurt?

    Patients are quick to complain when a medical ointment stings after application. But there may be another reason that they might be dissatisfied with the way an ointment behaves when it is too thick. By Bob McGregor, General Manager, Brookfield Engineering

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  • QC Testing: Quality Control Methods That Make A Difference
    QC Testing: Quality Control Methods That Make A Difference

    By Robert McGregor, Global Marketing and High End Product Manager, Brookfield Engineering Laboratories, Inc.

    How do you bring consistency to QC testing? Pharmaceutical products that meet manufacturability criteria and provide high level consumer satisfaction undergo a battery of tests before being distributed to the consumer. Using affordable instrumentation to perform QC tests, which certify that tablets, capsules, elixirs, ointments, etc. have the right physical properties, is essential for today’s successful business.

  • How To Benchmark Powder Flow Behavior

    Unfortunately, there are many variables that affect a powder’s formulation. Consequently, the flow behavior cannot be guaranteed from formulation alone.

  • Challenges & Opportunities: Encapsulation Of Liquid & Semi-Solid Formulations Into Oral Capsules

    The encapsulation of liquids and semi-solids provides solutions for convenient delivery through improved oral absorption of poorly water-soluble drugs.

  • Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System
    Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System

    Formulation scientists have become pivotal to pharmaceutical development, in that they are often faced with the daunting challenge of not only identifying the most suitable drug delivery platform among a myriad of options, but also developing and validating robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames. By Eduardo Jule, Ph.D., Senior Manager, Formulation and Pharmaceutical Development

  • Solutions To Batch Mixing Issues

    This white paper presents some strategies for improving commonly encountered batch mixing problems. Because mixing processes vary from one application to another – with different objectives, design configurations, rheologies, operating limitations, etc. – there are no fix-all solutions that will apply to every situation.

  • Raising Expectations Of Excipients

    An excipient’s role has traditionally been viewed as merely a filler or binder contributing to the stability of the end product. The full value that a formulation can bring to a final dosage form; or the real importance of ensuring an excipient’s quality and performance; are often underestimated, overlooked, misunderstood, or disregarded. In reality, the functionality of the excipient can help determine whether or not a drug succeeds or fails. By Fred Monsuur, Julia Poncher W. R. Grace & Co

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