Does The Ointment Hurt?
Patients are quick to complain when a medical ointment stings after application. But there may be another reason that they might be dissatisfied with the way an ointment behaves when it is too thick. By Bob McGregor, General Manager, Brookfield Engineering
WHITE PAPERS & CASE STUDIES
How To Benchmark Powder Flow Behavior
Unfortunately, there are many variables that affect a powder’s formulation. Consequently, the flow behavior cannot be guaranteed from formulation alone.
Challenges & Opportunities: Encapsulation Of Liquid & Semi-Solid Formulations Into Oral Capsules
The encapsulation of liquids and semi-solids provides solutions for convenient delivery through improved oral absorption of poorly water-soluble drugs.
Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System
Formulation scientists have become pivotal to pharmaceutical development, in that they are often faced with the daunting challenge of not only identifying the most suitable drug delivery platform among a myriad of options, but also developing and validating robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames. By Eduardo Jule, Ph.D., Senior Manager, Formulation and Pharmaceutical Development
Solutions To Batch Mixing Issues
This white paper presents some strategies for improving commonly encountered batch mixing problems. Because mixing processes vary from one application to another – with different objectives, design configurations, rheologies, operating limitations, etc. – there are no fix-all solutions that will apply to every situation.
Raising Expectations Of Excipients
An excipient’s role has traditionally been viewed as merely a filler or binder contributing to the stability of the end product. The full value that a formulation can bring to a final dosage form; or the real importance of ensuring an excipient’s quality and performance; are often underestimated, overlooked, misunderstood, or disregarded. In reality, the functionality of the excipient can help determine whether or not a drug succeeds or fails. By Fred Monsuur, Julia Poncher W. R. Grace & Co
Steps To Increase Energy-Efficient Mixing
This white paper explores five ways to increase energy efficiency in new and existing mixing processes. By Christine Banaszek