Development & Manufacturing White Papers & Case Studies
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Creating An Effective Pre-Clinical Model Of Bone Marrow
4/9/2024
A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation in vitro model.
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
4/8/2024
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.
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Manufacturing Challenges With High Concentration Biologics
3/18/2024
Explore key process operations, some of the challenges in manufacturing high-concentration biologics, and factors to consider for process optimization.
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Frontage Takes The First Step In Creating Their Intelligent Laboratory
3/15/2024
Learn how the implementation of a lab management system has enabled Frontage to accelerate its operations and initiate its journey toward establishing a truly intelligent laboratory.
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Proximal Tubule Kidney-Chip For Modeling Human Physiology
3/14/2024
Discover how an Organ-Chip can be used to create a comprehensive recapitulation of the proximal tubule, addressing the need for more human-relevant preclinical models in the pharmaceutical industry.
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Duodenum Intestine-Chip For Modeling Human Physiology
3/14/2024
Discover an Intestine-Chip that integrates the robust cell sourcing of organoids with Organs-on-Chips technology to overcome experimental limitations and yield a closer-to-human transcriptomic profile.
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Development And Characterization Of The Species-Specific Liver-Chip
3/14/2024
There is a growing need for more human-relevant preclinical models. Explore how Organ-Chips offer a viable solution and can be used to create a comprehensive recapitulation of the liver sinusoid.
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Characterization Of The Colon Intestine-Chip
3/14/2024
Learn about the development and characterization of Organ-Chips and what makes them the most comprehensive model of the colonic epithelial-endothelial interface that is commercially available.
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Testing The Transduction Of AAV-Based Therapeutics
3/14/2024
Organ-on-a-Chip technology has emerged as a solution to the limitations of conventional preclinical models. Learn how Liver-Chips can be used to test the delivery efficiency and safety of AAV vectors.
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Modeling Inflammation-Specific Immune Cell Recruitment
3/13/2024
Traditional models for studying inflammatory bowel disease (IBD) often fall short. See how the Colon Intestine-Chip was used to model the progression of IBD driven by immune cells more completely.