Product/Primary Packaging White Papers & Case Studies
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Protecting Pharmaceuticals From Degradation
Pharmaceuticals are subject to a variety of degradation pathways that compromise drug safety and shelf-life. By far the greatest degradation is caused by hydrolysis and oxidation. However, other mechanisms include racemization, photodegradation, elimination, and complexation. By Adrian Possumato
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Eliminate Inspection Labor Costs On Your Blister Packaging Lines
Production of tablets and capsules is carried out in cleanrooms and under stringent procedures as per GMP requirements. However the process also relies on machines and machine operators whereby misappropriate handling can result in a faulty blister pack containing micro leaks in the packaging thus allowing air and moisture to enter the blister and damage the product. By Giuseppe Bonfiglioli
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Four Reasons For The Rise In Blister Packaging
Explore the factors that are driving blister packaging to the forefront of pharmaceutical packaging, and at an even faster rate than its current growth.
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Discussion Of Vial Closures And Stoppering Force In Pilot Freeze-Dryers
To answer the often asked question "Can my system stopper a full tray of the vials and stoppers I have selected?,", it is important to be able to recognize the force needed for your particular container-closure system and to compare that to the stoppering pressure specification provided by the freeze dryer manufacturer. By Leslie Mather
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Fumigation Within A Pharmaceutical Aseptic Filling Line
Bioquell's Room Bio-Decontamination Service was required for a major multi-national pharmaceutical company needed a solution that woul removed Staphylococcus edpdermidis from specific zones in an aseptic filling line with areas ranging from European GMP Grade A to Grade D. The solution neeeded to meet FDS regulatory requirements and have proven efficacy documentation againt S. epidermidis.
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Meeting Technical Challenges In Desiccant Dispensing
Christopher Garrod knew he would need a desiccant in his sample bottles of Vimovo, but after speaking with his R&D team, Garrod, a senior engineer on the Packaging Process Execution Team for AstraZeneca, immediately realized it would present a unique challenge. Vimovo, a fixed-dose combination of enteric-coated naproxen and immediate release esomeprazole, is a highly moisture sensitive drug. The atmospheric exposure limits for the desiccant were a lot tighter than any product they had packaged before, presenting Garrod with his first challenge
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Ophthalmic Product Package Inspection
Ophthalmic products come in a variety of package formats. The liquid-filled packages are often soft containers with snap-on or screw caps, and include foil lidded blister packs for single-use contacts.