Outsourcing Solid Dose Manufacturing Trends In 2014
In 2014, the contract manufacturing market for solid dosage forms is anticipated to be $19.6B, representing 58% of the total CMO market value of $33.7B. While the market value percentage for solid dose has been drifting downward — likely related to the shift towards biologics, which are more expensive to develop and manufacture — the propensity to outsource oral solid dosage forms continues to grow modestly.
WHITE PAPERS & CASE STUDIES
Case Study: Bag Handling, Check Sieving, Weigh System
In this installation, materials are received in 50-pound bags and semi-bulk bags and are security screened for foreign objects while being conveyed to a weigh hopper, where they are automatically hatched in predetermined weights and discharged into process drums.
Novel Controlled Release Formulation For Orally Disintegrating Tablets Using Ion Exchange Resins
Oral disintegrating tablets (ODTs) are designed to disintegrate rapidly in the mouth upon contact with saliva (≤ 30 seconds) and allow oral drug delivery without chewing or a need for water. By Abhijit Gokhale and Praba Sundararajan, Pharmaceutical Development Services, Patheon Pharmaceuticals Inc.
When Powders Fail To Flow
There are many traditional measurement methods for characterizing the “flowability” of powders: angle of repose, flow cup, tap test. Practitioners know that the information may not be useful some of the time, but experience helps to separate the meaningful test results from those that may be suspect.
Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance
Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder
Film Coating For Pediatric Oral Solid Dosage Forms
From a recent survey conducted within the pharmaceutical industry, by Colorcon, it was confirmed that oral solid dosage forms are a preferred choice for formulation of pediatric medicines.
A Unique Solution To Dramatic Yield Increase Through Use Of Anti-Segregation Technologies
A unique solution improves yields from less than 75% to over 98%.