Development & Manufacturing White Papers & Case Studies
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Accurate HC-LC Pairing And A Close-To-Nature Solution For bsAbs
9/11/2023
Examine how a proprietary technology ensures high levels of accurate HC-LC pairing without detriment to critical quality attributes such as titer, binding affinity, stability, and immunogenicity.
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mRNA-LNP Nucleic Acid Assessment From Distinct Formulations
9/8/2023
Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.
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Could RFID-Based Unit-Level Traceability Be Key To Operational Excellence?
9/5/2023
Radiofrequency identification (RFID)-based unit-level tracking solutions for prefilled syringes are poised to help pharma manufacturers address key risks and costly bottlenecks related to the fill-finish process.
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Structural Characterization Of The Cationic LNP Component
8/31/2023
Gain a deeper understanding of how EAD is used when characterizing ALC-0315 and its impurities, as well as identify the nature and site of chemical alterations in ALC-0315 resulting from forced degradation.
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Comprehensive Peptide Mapping Of Protein Therapeutics
8/31/2023
Explore how the peptide mapping workflows templates provided by a software designed for the characterization of biotherapeutic digests alongside data visualization and interrogation.
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Sterile Filtration And Quality Risk Management
8/31/2023
Process control is essential for manufacturing sterile products. Explore the role of filtration for bioburden control in quality risk management and contamination control strategies.
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LCMS/MS Methodology For Mapping Disulfide Linkages In Etanercept
8/28/2023
Learn about the details surrounding the comprehensive mapping of disulfide linkages in etanercept using the EAD approach on an analytical characterization system.
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Characterize Deglycosylated NISTmAb Using icIEF-UV/MS
8/28/2023
Examine a comprehensive analysis of deglycosylated NISTmAb (dgNISTmAb) using a novel integrated icIEF-UV/MS workflow.
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Direct And Rapid Multi-Attribute Monitoring Of Multiple Intact mAbs
8/28/2023
What are the results of an innovative system for direct chip-based integration of icIEF with mass spectrometry (MS) being utilized to characterize mAbs spanning a wide pl range?
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Electron Activated Dissociation Workflow For Biotherapeutics Characterization
8/28/2023
Explore the benefits of an electron-activated dissociation middle-down workflow, including the ability to achieve high sequence coverages (70%-80%) of monoclonal antibody subunits in a single injection.