Development & Manufacturing White Papers & Case Studies
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PBPK Modeling For Optimized Controlled Release Formulation Development
8/24/2023
Examine the benefits of controlled release, the application of PBPK modeling in controlled release formulation development, and how modified release products can be developed to deliver optimal patient outcomes.
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Recommendations For Successful IND Approval Of RNA-LNP Drugs
8/22/2023
The existing regulatory system is ambiguous for RNA therapeutics. Leverage this Investigational New Drug (IND) guide to help accelerate and strengthen the process IND filing of novel nanomedicines.
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Combining Single-Cell Isolation And Microplate Imaging To Improve Cloning Efficiency
8/21/2023
Improve your cloning efficiency with higher assurance of clonality by using a combination of single-cell isolation and microplate imaging.
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Employ An icIEF-UV/MS Workflow For The Reproducible Separation Of NISTmAb Variants
8/15/2023
Review data that supports the reproducibility of a streamlined icIEF-UV/MS workflow for charge variant separation, UV quantitation, and peak identification of monoclonal antibodies (mAbs) by coupling two systems.
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Direct And Rapid Multi-Attribute Monitoring Of Intact Monoclonal Antibodies By icIEF-UV/MS
8/14/2023
Explore a novel integrated workflow and system that offers direct chip-based integration of imaged capillary isoelectric focusing (icIEF) with mass spectrometry (MS).
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A New Approach For High-Resolution Full And Empty AAV Capsid Analysis
8/14/2023
Utilize a high-throughput method for comprehensive AAV evaluation on a single CE platform for high-resolution full and empty AAV capsid analysis.
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Characterize Lentiviral Vector Quality Attributes Using CE Platform Technology
8/14/2023
Review this outline of a platform-based approach using capillary electrophoresis (CE) to mitigate the technical difficulties in characterizing LVVs for the assessment of multiple quality attributes.
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N-Linked Glycan Analysis Of NISTmAb
8/11/2023
With the right glycan analysis kit, you can achieve a 1-minute-per-sample analysis rate, along with streamlined and high-throughput glycan analysis assay for all phases of biopharmaceutical development.
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Released N-Linked Glycan Analysis
8/9/2023
Review a streamlined N-linked glycan analysis that employs an automated sample preparation with the magnetic bead-mediated glycan workflow followed by capillary electrophoresis.
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Reproducibility Study Of A High-Throughput Released N-Glycan Workflow
8/9/2023
This fast glycan labeling and analysis kit demonstrated that it could yield 576 data points from 2 instruments, 2 cartridges and 3 chemistry kits during inter- and intracapillary reproducibility validation.