Multisorb Technologies And Neutroplast Partner To Offer Desiccant Closure System For HDPE Pharmaceutical Bottles

Multisorb Technologies, the global leader in advanced active packaging technology, announced recently that it has partnered with Neutroplast Indústria de Embalagens Plásticas, S.A to offer a Multiform Coated Solid Form (CSF) Closure System for high-density polyethylene (HDPE) pharmaceutical bottles. The system combines Multisorb's Multiform CSF concentrated desiccant with Neutroplast's screw closure.

With other similar closure systems, desiccant function is compromised by moisture from the drug product that utilizes initial adsorptive capacity immediately after packaging. The Multiform CSF Closure System overcomes this deficiency by offering twice the desiccant capacity, protecting the drug product from moisture-mediated degradation while also functioning as an active barrier system, inhibiting moisture ingress through the bottle–closure system joint.

The Multiform CSF is a compact silica gel desiccant that utilizes condensed density technology. Fitted into the Neutroplast's screw closure as part of the container closure system, it serves as an active barrier, adsorbing moisture ingress rather than merely blocking it as in static barrier systems.

The closure system's desiccant offers double the amount of adsorbent capacity per cubic centimeter of space compared to similarly sized silica gel desiccants. It actively desiccates the product to reduce the rate of chemical degradation and stabilize the drug formulation during storage and transport.

"The key advantage this system offers is its dual functionality," says Adrian Possumato, Global Director, Healthcare Packaging at Multisorb Technologies. "Working closely with Neutroplast, we have been able to design a closure system that serves as an active barrier as well a highly effective desiccant, reducing molecular mobility in the drug product to ensure stability and extend shelf life."

The Multiform CSF has a pharmaceutical grade coating that allows for direct product contact and can be manufactured under advanced aseptic conditions. It has a Drug Master File available and is constructed with FDA-approved materials.

About Multisorb Technologies
Multisorb Technologies has been an innovator in sorbent technology for over 45 years. Founded in 1961 by John S. Cullen to protect products against the damaging effects of moisture, today Multisorb is the world leader in the development and production of active packaging components.

Multisorb's corporate offices are located at 325 Harlem Road, Buffalo, New York 14224 USA. For more information E-mail: info@multisorb.com; Website: www.multisorb.com.

Multisorb's European Headquarters are located at: Unit 30 Rufford Court, Hardwick Grange, Woolston, Warrington, Cheshire WA1 4RF United Kingdom.

SOURCE: Multisorb Technologies