INSIGHTS ON LIQUID DOSE MANUFACTURING
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What Does Annex 1 Mean For Cryovial Filling?
New sterile manufacturing rules require major changes to cryovial filling. Ensure compliance by adopting better "first-air" protection, minimizing human contact, and using 100% dose checks.
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Robust, High-Throughput Automated Solution For Water Endotoxin Testing
High-throughput water endotoxin testing doesn’t have to sacrifice consistency. Gain insight into how an automated workflow delivers reliable results, low variability, and strong control recovery.
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Digital Twin For Fill-Finish: Overview And Use Cases
Digital twin technology optimizes aseptic fill-finish through real-time mirroring and predictive simulation. Improve yields and validate complex recipes by integrating dynamic virtual models.
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Future-Proofing Aseptic Manufacturing
Investing in adaptable aseptic manufacturing pays off. Find out how flexible systems, despite higher initial costs, handle complex drugs and changing volumes to boost productivity and quality.
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Step Into The Future Of ATMP Fill-Finish5/21/2025
Discover the future of ATMP manufacturing as Josh Russell from AST demonstrates an advanced, fully automated fill-finish system featuring automated bag and tub opening, as well as the Atmos isolator.
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How Can You Avoid Bioprocessing Risks When Using Cable Ties?10/15/2025
Cable ties in bioprocessing can cause leaks, damage, and delays. See how switching to a uniform-sealing connector can significantly improve efficiency, reduce prep time, and minimize contamination risks.
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Customer Story: Emergent BioSolutions Enhances Aseptic Filling Process1/9/2026
Upgrading outdated filling systems is essential for meeting future production demands and regulatory standards. Learn how one manufacturer modernized its approach to ensure compliance and efficiency.
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Ensuring Integrity: Testing Viscous Biologics In Pre-Filled Syringes12/18/2025
Viscous biologics in pre-filled syringes demand precise integrity testing. Discover how advanced HVLD technology detects micro-defects and ensures sterility, meeting stringent USP <1207> standards.
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Enable Low Volume Delivery Of Proteins In Aqueous Solutions11/7/2025
Achieve ultra-low volume dispensing of proteins and aqueous solutions without surfactants with consistent precision, minimal contamination, and broad compatibility to streamline your lab workflow.
LIQUID DOSE MANUFACTURING SOLUTIONS
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- Advanced Technology
- Laboratory, stability/clinical trial, 503b, vaccine, biologic, small scale production capable Blow/Fill/Seal system
- Extremely versatile, small-footprint machine
- Single-Use Technology (SUT) or CIP/SIP configuration
- All Electric-Servo motion controls
- Stepped-base design for easy maintenance and changeover
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Process stability, high efficiency and customizable features are crucial issues related to glass packaging manufacturing. Our ampoule forming line perfectly matches these needs, guaranteeing the highest performance thanks to cutting-edge capabilities, such as its automatic inspection system and electric rotational oven, which provides higher product handling stability.
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Efficient purification requires scalable chromatography and advanced automation. Explore how customizable systems and precision software optimize results for peptides, proteins, and oligonucleotides.
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AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.
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AST’s Container Closing System (CCS) is a benchtop, semi-automatic machine that provides complete and accurate control of the syringe and cartridge closing process. The Container Closing System is able to close syringes or cartridges using both vacuum and vent-tube methods for a wide range of container sizes quickly and easily with only a few format part changes.