INSIGHTS ON LIQUID DOSE MANUFACTURING

• Vessel Charging For IV Liquids Preparation

  A customer had planned a new facility for the production of intravenous liquids. They were facing a challenge of charging multiple vessels with salt, glucose and active carbon under controlled conditions achieving high accuracy. See what solution allowed them to create a highly automated high capacity facility.

• Can Glass Prefillable Syringes Meet The Requirements Of Deep Cold Storage Conditions?

  Explore the challenges imposed by deep cold storage conditions and outcomes on functional performance, sub-visible particles performance, and container closure integrity related to prefillable syringes.

• SP Hull LyoStar® 4.0 R&D & Process Development Freeze Dryer

  The SP Hull LyoStar 4.0 is ideal for rapid lyophilization cycle development, optimization and scale-up, and incorporates the very latest innovations in freeze-drying technology to protect valuable product by ensuring precise process control and robust reliability.

• Maximize Productivity With The GENiSYS® R

  GENiSYS^® R provides ultimate flexibility for processing ready-to-use vials, syringes and cartridges on a single machine. Highly reliable robotics and recipe driven changeovers allow for complete format changes in as little as 30 minutes. Maximize productivity and return-on-investment with the GENiSYS R.

• Agglomerate-Free Dispersion For Hand Sanitizers

  12/29/2020

  Obtaining an agglomerate-free dispersion is essential to ensure a clear, bright gel after neutralization but low density powders such as Carbopol can be difficult to incorporate into liquids with a conventional agitator. The high shear mixing of a Silverson mixer ensures rapid incorporation and dispersion of powders to form an agglomerate-free solution, with minimized aeration.

• Software Tools For Pharmaceutical Lyophilization Process Development

  1/11/2022

  Read highlights from a recent webinar describing a software modeling tool developed to optimize conditions for the primary drying cycle and while accounting for heterogeneity within and between batches of drug products.

• SP Hull Versa-Line Fill-Finish Solutions

  8/6/2020

  The SP modular Versa-Line fill-finish system and Line of Sight™ freeze dryer tools, technologies and equipment provide product development and configurable full line solutions.

• GENiSYS® Lab Semi-Automatic Systems

  8/7/2020

  AST’s GENiSYS® Lab semi-automatic systems are ideal for drug product development and cGMP production applications. Each system automates the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. GENiSYS Lab offers a perfect balance between automated features, size and affordability without compromising quality, safety and ease of use.

• Interplay Of Formulation Components On Excipient Functionality During Lyophilization

  1/11/2022

  A recent webinar described the complex effects of combining excipients in a formulation and the importance of determining optimal concentrations and processing conditions for lyophilization of protein formulations.