INSIGHTS ON LIQUID DOSE MANUFACTURING
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AST Virtual Pharma Expo May 2024
View this demonstration of a flexible, modular fill-finish machine featuring a fully integrated HMI and automated processing of nested, custom, and ready-to-use vials, syringes, and cartridges.
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Biofluorescent Particle Counters Are Gaining Momentum
The 2025 BioPhorum report highlights challenges and trends in drug filling operations and how they are advancing towards biofluorescent particle counters. Discover an approach that aligns with industry needs.
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Achieve Your Commercialization Goals For Sterile Injectables
You can count on our extensive scientific and manufacturing expertise, stringent quality standards, and highly responsive customer service to ensure timely delivery of your life-changing products.
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EU GMP-Annex 1: Changes, Challenges, And Ready-To-Use Sterile Packaging
Leveraging a pre-sterilized containment solution that meets the requirements of Annex 1 and outsources non-core activities can help prevent contamination and reduce the effort and liability of the CCS.
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Afton Scientific Capabilities Update January 2026: Fill/Finish1/27/2026
Here, Michael Dunn outlines our current available capacity, including RABS operations, alongside the commissioning of a new Annex 1–compliant isolator filling line and expanded QC capabilities to ensure reliable, scalable execution.
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Minimizing Particulate Risk5/13/2026
While visible particles often draw immediate attention, visual inspection alone is insufficient, as subvisible particulate matter can pose equally significant risks to patient safety.
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Barrel Filling Vs. Tip Filling A Syringe – Which Approach Should Be Used?1/3/2025
There are two primary filling methods for pre-filled syringes. Explore the pros and cons of each approach, highlighting why barrel filling is generally preferred in the pharmaceutical industry.
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BioTitan Retention Device Overview5/29/2025
Learn about a retention device that provides robust fortification for single-use assemblies. Its 360-degree seal strengthens connections, reduces leak risks, and ensures process integrity for fluid transfer.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
LIQUID DOSE MANUFACTURING SOLUTIONS
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Leverage a pre-verified, integrated syringe platform. Accelerate timelines and reduce costs by eliminating drug-independent testing while streamlining regulatory submissions through one source.
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AST’s ASEPTiCell® is a flexible fill/finish system that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.
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Used 300 sq ft BOC Edward freeze dryer, model LYOMAX 28, 316L stainless steel product contact surfaces with (13) 1170 mm wide x 1850 mm deep usable shelves, 115 mm shelf spacing, stoppering, external condenser with 300 kg ice capacity, refrigeration and vacuum skid with liquid natural gas refrigeration, model AV-LUS BOC Edward loading / unloading skid, 480 volt with controls, freeze dryer serial# MTE1930, built 2004.
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AST’s ASEPTiCell® and GENiSYS® systems combine industry-proven technologies such as robotics and isolator-barrier systems to provide flexible pharmaceutical aseptic filling and closing of ready-to-use vials, syringes, and cartridges with a single machine. These innovative platforms use a modular design approach to provide a truly adaptive system with the capabilities and features necessary for cGMP production of clinical and commercial sterile injectable products.
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A technically superior, cGMP-compliant product, the AST Atmos Isolator features a groundbreaking user-friendly design, enhanced automation and efficiency, robust sterility assurance, and a disruptive VPHP solution providing industry-leading bio-decontamination cycle times.