INSIGHTS ON LIQUID DOSE MANUFACTURING
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From Complexity To Confidence In Prefillable Syringe Transfer
Discover how aligning packaging strategy with technology transfer requirements can accelerate timelines, control costs, and support successful injectable drug product manufacturing.
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Sterile Injectables: Why Innovation Matters More Than Ever
New technologies and regulatory changes are shaping safer, more efficient filling processes. Discover why innovation is key to protecting patients and advancing therapies.
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Three Key Actions To Minimize Dead Volumes
Minimizing liquid dead volume helps labs conserve costly reagents and scarce samples while boosting assay throughput. Learn how advanced liquid level detection technologies are driving efficiency.
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Simulating PUPSIT Or Gas Purges In Bacterial Challenge Tests
Managing PUPSIT‑related risks is a critical part of contamination control. Learn how bacterial retention studies, wetting fluids, and downstream practices influence sterility assurance.
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Reading Between The Lines: How To Evaluate Decontamination Cycle Time Claims8/19/2026
Comparing isolator decontamination cycle times requires evaluating key variables like aeration endpoints and load patterns to build accurate capacity models and avoid costly delays.
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Flying On Two Wings: Balancing Local Agility And Global Quality In China8/12/2026
As China expands its role in drug development, injectable therapy programs face new demands. Learn how manufacturers are scaling quality, devices, and production for global success.
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Ensuring Integrity: Testing Viscous Biologics In Pre-Filled Syringes12/18/2025
Viscous biologics in pre-filled syringes demand precise integrity testing. Discover how advanced HVLD technology detects micro-defects and ensures sterility, meeting stringent USP <1207> standards.
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Isolators For Pharmacy Compounding – Time For Change?3/14/2025
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
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Stability Issues Unique To Liquid Injectables And How To Avoid Them3/23/2026
Liquid injectables face stability risks like oxidation, hydrolysis, aggregation, temperature shifts, and packaging effects, requiring early, rigorous formulation and process controls.
LIQUID DOSE MANUFACTURING SOLUTIONS
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From stick packs and packettes to multi-use, recloseable flexible packaging, engineered for performance, superior barrier protection, and standout shelf appeal.
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Nunc EasyFill Cell Factory system, with its versatile port design, accommodates both pouring and aseptic filling techniques. The design features both a large, easy-to-fill 33mm vented screw closure and a traditional plug 'n' play port, eliminating the need for additional accessories. It is truly an “out-of-the-box” solution or both research and commercial scale cell culture applications.
- Versatile port design for pouring and aseptic filling techniques
- “Out of the box” solution – no additional accessories required
- Traditional Cell Factory features:
- Space saving format: One 10-layer EasyFill Cell Factory equals 36 x T-175 flasks
- Linearly scalable from research to commercial scale applications
- Reduces the risk of contamination (less interactions vs. flasks and roller bottles)
- Nunclon Delta certified ensures performance consistency from lot to lot
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Open RABS as a housing for aseptic processes, e.g., filling, loading, and unloading of freeze dryers. Product protection is achieved by a barrier (oRABS housing with gloves) between the operator and the product.
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Having the right balance of capacity and capabilities in all market conditions is the struggle that Contract Manufacturer Organizations face daily. Add to it the cost and complexity of maintaining a suitable parenteral manufacturing facility, the risks can be high. With constantly evolving parenteral market needs, having flexibility while achieving high utilization is key to long term success. To support these challenges, AST’s line of aseptic and syringe filling and closing machines provide adaptive fill-finish capabilities to ensure that any contract manufacturing organization has the right capabilities for any vial, syringe filling or cartridge application.
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Specialist in Aseptic Fill-Finish and packaging of Cartridges, pre-filled syringes (PFS) and vials.