INSIGHTS ON LIQUID DOSE MANUFACTURING
Determining And Controlling Oxygen Levels In Sensitive Formulations
This webinar will review how oxygen levels in finished parenteral drug containers can be determined and controlled throughout the product life cycle by using laser-based headspace analysis.
Toxic Treatments: Controlling Exposure Risks In ADC Manufacturing
The potency and effectiveness of the ADCs are dependent upon engineered nanoparticles (ENPs), but little is known about the environmental and human health hazards posed by ENPs.
The Challenges Batch And Continuous Manufacturing Bring To Containment Product Design
Methods and techniques used in pharmaceutical manufacturing are broadly reviewed. There are two basic models of pharma manufacturing: batch and continuous. Both approaches are defined. It is concluded that both approaches have elements of the other. Generally speaking, many pharma manufacturing procedures are transitioning from the batch to the continuous approach.
Recommended Blending Equipment For Nutraceuticals
Dry blending is an indispensable operation in the manufacture of multivitamins, sports supplements, herbal extracts, meal-replacements, green food powders and other nutraceutical products.
Sterile Production Process Studies Using 100% Headspace Inspection Of Finished Product
This app note describes the application of the PULSAR inspection platform to perform 100% headspace oxygen monitoring during the filling of oxygen-sensitive formulations, 100% container closure inspection of suspect batches, moisture inspection of freeze dried product, and automated media fill inspection.
CCI Testing And Revisions To EU Annex 1
The new language in EU Annex 1 will likely have a significant impact on your CCI testing practices. In this webinar CCI testing strategies and the proposed revisions to EU Annex 1 are discussed.
Nitrogen Purge Optimization And Validation Of Sterile Liquid Filling Lines
Large molecule biopharmaceuticals can be prone to oxidation and to prevent this from occurring, the headspace is often purged with an inert gas during filling to ensure a longer shelf life.
Scale-Up And Tech Transfer From 100 L SIP/CIP Vessel To The 300 L S.U.F.
A collaborative study with a new customer with the objective of taking an existing, smaller preclinical E. coli process previously performed in stainless-steel vessels and scaling it up quickly.
Implementing FDA Guidance: CCI Testing In Lieu Of Sterility Testing
This application note details FDA released guidance titled “Container and Closure System Integrity Testing in Lieu of Sterility Testing as a Component of the Stability Protocol for Sterile Products."
LIQUID DOSE MANUFACTURING SOLUTIONS
Flow Sciences Lab Design
Whether you are designing a new laboratory or renovating an existing facility, it’s important to consider the fitness and applicability of fume hoods. Flow Sciences’ Saf-T-Flow™ Fume Hood Series are ducted for maximum safety and efficiency with minimum energy input.
Versa Frame 8120 Chain Checkweigher
The Thermo Scientific™ Versa Frame 8120 checkweigher offers a rugged chain design that is easy to clean and maintain. The simplified design with minimal moving parts enables high rates and superior accuracy weighing in many applications and is ideal for weighing cartons, cans, bottles and rigid packages.
Aseptic Fill/Finish Services
Based in the U.S., Pii’s aseptic capabilities, combined with strong PharmaceucticsKnow-How™, is positioned to deliver quality and on-time drug product for your clinical and commercial needs.
Used Groninger Liquid Filling Packaging Line
Used Groninger plastic bottle filling line, consisting of Groninger orienter and feeder, model ZVB 850, with (2) bottle vibrating sorting bowls with independent feed hoppers, serial# 6911, Groninger inline intermittent motion filler, model DMK 8001, walking beam bottle indication, (8) head filling station with independent mass flow meters per filling head with buffer tank, bottle deionization station, bottle blow-out and aspirating station, currently set up for 45 mm diameter x 35 - 200 mm high bottle, 2 - 15 ml fill capacity, serial# 6912, integrated Groninger CIP/SIP system, serial# 6913, Groninger dropper inserter, model KVK 112 A with bowl feeder and dropper verification system, serial# 6914, Groninger capping and torquing unit, model KVK 108, with bowl feeder and cap verification system, serial# 6915, reject, Siemens S7 plc controls with Siemens MP370 HMI. Line currently set up for 3 ml plastic bottles up to 13200/hr. 230/400 volt, 50 hertz, 3 phase, mounted in RABS unit. Line built 2007.
Saltus® Single-Use Mixing System Brochure
Saltus® mixing systems are based on a design philosophy which emphasizes usability and automation. From the easy to install, self-deploying, single-use mixing assembly to the fully automated, one-button start of the control system, Saltus® mixers provide unparalleled usability and ease of operation.