INSIGHTS ON LIQUID DOSE MANUFACTURING
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2R Vials And Deep Cold Storage - Determining Mechanical & CCI Performance
Review the implications of this study on the storage of sensitive molecules that require deep-cold storage and learn how 2R Fina glass vials are poised to enhance cold storage practices.
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A Micronization Method Enabling The Formulation Of Biopharmaceuticals
Micronization is key for increasing the loading efficiency and lowering the burst of microspheres. Applying lyophilization-based micronization methodology at a small scale helps to support challenging formulation development projects.
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Key Considerations When Filling Dual Chamber Syringes
Dual-chamber syringes (DCSs) are in high demand across the pharmaceutical and hospital industries. Learn about the challenges of the DCS filling manufacturing market and how to overcome them.
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How A Flexible Approach To Autoinjector Assembly Can Be Advantageous
Examine how a flexible, scalable, and efficient solution for the assembly of autoinjectors can help you stay ahead of the competition and meet the demands of an ever-changing industry.
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Accelerating SARS-CoV-2 Immunotherapy Speed To Clinic4/26/2024
A clinical-stage biotherapeutics company developing a COVID-19 immunotherapy searched for a solution to the difficulties it faced in scaling up its manufacturing operations due to limited resources.
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Glass Vials To Evolve Your Sustainability Goals5/15/2024
Learn more about new glass vial options that combine performance and sustainability to help pave the way to a greener future.
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4 Factors To Consider When Scaling Up7/18/2023
It's essential to understand how scaling up is affecting your aseptic filling operations. Here are four topics to consider to help ensure your drug product will be taken care of and ready for production.
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Optimizing Aliquoting For Robust Cell And Gene Therapy Processes6/3/2024
Explore the challenges of liquid handling in cell and gene therapy processes as well as innovative solutions to simplify aliquoting in modern bioprocesses.
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Successful Planning: Process Liquid & Buffer Preparation6/23/2023
Obtain an accurate total cost of ownership assessment through understanding common operational inefficiencies, risks, and financial burdens associated with process liquid and buffer preparation.
LIQUID DOSE MANUFACTURING SOLUTIONS
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AST’s GENiSYS® C is an advanced, yet compact, filling and closing system for automated processing of nested, custom and ready-to-use vials, syringes, and cartridges. With many features typically found in large scale filling machines, the GENiSYS C’s compact footprint makes this system ideal for use in small scale filling applications, including R&D, process development, engineering runs, niche product manufacturing, and even cGMP clinical and small-batch commercial manufacturing.
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Freeze dryer processes for pharmaceutical products require robust equipment and quality designs. Dec offers automated solutions for loading and unloading lyophilization systems. With our modular design approach and in-depth knowledge on this type of systems, we offer fixed or flexible loading solutions for any lyophilizer.
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DCS® Liquid was specifically developed for toxic and corrosive liquids, achieving containment levels of < 1 ppb. The safe and contained emptying and filling of drums is thus made possible without additional precautions, such as full protective clothing or large laminar airflow booths.
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OFM automatic filling and closing machines are designed for pharmaceutical formulations, such as syrups, ophthalmic products, and nasal sprays either in glass or plastic containers.
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AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.