INSIGHTS ON LIQUID DOSE MANUFACTURING
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Biofluorescent Particle Counters Are Gaining Momentum
The 2025 BioPhorum report highlights challenges and trends in drug filling operations and how they are advancing towards biofluorescent particle counters. Discover an approach that aligns with industry needs.
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Finding The Right Aseptic Processing Approach
How should you approach building your aseptic processing line? Gain insight into the advantages of using a modular, configurable technology rather than custom fill-finish solutions.
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Contamination Control Strategies: Comparing Cleanrooms, RABS, Isolators
Sterile manufacturing relies on three main contamination control strategies (CCSs): cleanrooms, RABS, and isolators. Understand how each system compares in sterility assurance, startup cost, and operational flexibility.
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5 Key Questions On Implementing Pharma 4.0™ Solutions For Fill-Finish
Pharma 4.0 leverages IoT, AI, and automation to enhance drug quality. Evaluate your fill-finish line readiness by considering five key questions on modularity, high-risk process automation, and data integration.
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The Rise In Aseptic Manufacturing Solutions With Smaller Footprints2/19/2025
Aseptic drug manufacturing is going small. Discover how advanced robotic and automated systems with smaller footprints are changing the landscape and boosting accessibility.
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Thermo Fisher Scientific Large Volume Liquid Expansion5/2/2024
Take an insightful look into the expansion of the large volume liquids manufacturing site at the Grand Island facility, highlighting the various stages of the manufacturing process and the capabilities it offers to support the bioprocessing industry.
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A Direct Path To Annex 1 Compliance With Blow/Fill/Seal Technologies9/13/2025
Learn how Blow/Fill/Seal technology supports contamination control, reduces operator risk, and meets sterility assurance requirements under dynamic conditions with advanced airflow and monitoring.
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Enable Low Volume Delivery Of Proteins In Aqueous Solutions11/7/2025
Achieve ultra-low volume dispensing of proteins and aqueous solutions without surfactants with consistent precision, minimal contamination, and broad compatibility to streamline your lab workflow.
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2R Vials And Deep Cold Storage - Determining Mechanical & CCI Performance8/27/2024
Review the implications of this study on the storage of sensitive molecules that require deep-cold storage and learn how 2R Fina glass vials are poised to enhance cold storage practices.
LIQUID DOSE MANUFACTURING SOLUTIONS
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AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.
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Isolators with product protection as a housing for aseptic processes, e.g. filling, loading and unloading of freeze dryers.
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ProSys S06428 Containment and Sampling Technology is a single-chamber closed-barrier system providing protection from cross-contamination between a process and the surrounding laboratory. The Isolator is rated ISO5. (International Standards Organization) (for particle count) environment in operation. An integration with a bio-decontamination system allows parametric surface bio-decontamination and their ventilation systems, prior and after processes.
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Used 4.6 Sq Ft FTS Systems- SP Scientific freeze dryer Lyophilizer, model LyoStar 3, part# 100005824, with Praxair ControLyo nucleation on demand technology, stainless steel construction, with (3) approximately 11" wide x 20" deep usable shelves, 2.8" shelf spacing, -70/+60 c temperature range, 850 sq inch external condenser rated to -85 c, 30 liter ice capacity, bottom up shelf stoppering, integrated Oerlikon Trivac vacuum pump, refrigeration system with dual compressors, R404A and R508B refrigerant, 230 volt, 1007.7 run hours, serial# 320588.
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Explore process liquids preparation services and custom solutions for biopharmaceutical manufacturers.