INSIGHTS ON LIQUID DOSE MANUFACTURING
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Solve ATMP Aseptic Filling Challenges With Gloveless Isolators
Human intervention is the top contamination risk in ATMP manufacturing. Robotic gloveless isolators address that risk through full automation and real-time monitoring during aseptic filling.
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Product-Wet Integrity Testing: Risk-Based Strategies
When standard water‑based integrity testing falls short, product‑wet approaches can offer a more representative alternative. Learn how risk‑based strategies are used to establish reliable test limits.
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A Simple Method For Cell Growth Media Preparation
Explore how powder media and sterile fluid handling can reduce contamination risk and improve efficiency in viral vector production, especially for HEK293-based AAV workflows.
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AST Origins: Pioneering RTU Flexibility With Robotic Fill-Finish Systems
Modernize sterile manufacturing with robotic fill-finish systems. Achieve multi-format flexibility and risk reduction to meet the rigorous demands of personalized medicine and small-batch production.
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Streamline Your Path To Clinical Fill5/21/2026
Drug-independent PFS testing is a required early step — but it can be time-consuming and resource-intensive. What if you could eliminate the effort without losing the data you need?
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The Importance Of Tube Welding In Aseptic Bioprocessing3/9/2026
Sensitive biologics rely on aseptic processing and single‑use systems, making dependable sterile connections essential. See how tube welding offers a reliable way to reduce contamination.
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EZ-fill Smart™ Enhancing Aseptic Fill-Finish Efficiency In Pharmaceutical Manufacturing2/4/2025
Discover how the EZ-fill Smart system, integrated with Groninger technology, enhances aseptic fill-finish processes, improving efficiency, sterility, and scalability in pharmaceutical manufacturing.
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Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer11/21/2024
Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.
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Balancing Biologic Limitations And Patient Perceptions For An Enhanced Injection Experience11/4/2024
Discover an innovative sTW needle design reduces injection force and pain, enhancing comfort and ease for chronic patients while promoting long-term adherence through improved injection experiences.
LIQUID DOSE MANUFACTURING SOLUTIONS
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AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.
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Custom microscopy workstations to meet your advanced imaging needs.
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Medicines are highly sensitive to primary packaging components, which can affect compatibility with container closure systems. Discover Alba® syringes, designed for sensitive biologics, including highly concentrated drugs vulnerable to silicone interaction and ophthalmic medications.
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Ensure aseptic integrity with zoned downflow technology. These customizable modules purge contaminants to maintain ISO Class 5 environments for critical filling and research processes.
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For highly accurate and controlled filling and weighing of sterile liquids, our proven and reliable technology prevents costly overfilling. The easy to validate aseptic filling machines are compatible with all high-tech production facility equipment, software and processes known in the pharmaceutical primary packaging industry.