INSIGHTS ON LIQUID DOSE MANUFACTURING
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Barrel Filling Vs. Tip Filling A Syringe – Which Approach Should Be Used?
There are two primary filling methods for pre-filled syringes. Explore the pros and cons of each approach, highlighting why barrel filling is generally preferred in the pharmaceutical industry.
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What Your Biological Indicator Strategy Might Be Missing
While biological indicators have long been the industry standard for evaluating bio-decontamination cycles, faster, cheaper, and quantifiable contamination detection technologies are emerging.
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Ensure Stability And Safety Of Your Vaccine Formulations
Optimize vaccine production with integrated manufacturing, analytical testing, containment solutions, and automated inspection for efficient, reliable scale-up.
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Visual Inspection Equipment To Deliver The Highest Product Integrity
Gain insight into an advanced inspection solution for pharmaceuticals that ensures drug integrity and reduces costs with flexible technologies, from lab development to high-volume production.
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Agile Sterile Injectable Filling for Faster Market Entry9/21/2025
CMOs specializing in sterile injectable filling help pharmaceutical companies speed up product development and commercialization through flexible manufacturing, adaptability, and strong collaboration.
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UPLC Columns: Fundamentals, Chemistries, And Selected Small-Molecule Applications10/11/2024
Discover the fundamentals of UPLC columns and their diverse chemistries. Learn more about versatility in separating small-molecule analytes using reversed-phase and hydrophilic interaction techniques.
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Optimizing Cryovial Filling And Cryopreservation For Reliable Cell Functionality3/11/2026
Discover how controlled-rate, directional freezing maintains functional recovery even with lower DMSO concentrations, supporting consistent cell therapy manufacturing outcomes and enhanced batch reproducibility.
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Enhancing Biological Indicators With Enzyme Indicators6/30/2026
Achieve greater process assurance in decontamination cycles. Combining traditional indicators with rapid, quantitative enzyme data reveals performance trends to optimize validation.
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Scaling A Sterile Fill-Finish Program 4x Without Adding Complexity8/20/2026
Scaling sterile fill-finish operations requires balancing tight clinical timelines with flexibility. Single-use formulation systems eliminate major capital costs, reduce cleaning burdens, and speed turnarounds without sacrificing product quality.
LIQUID DOSE MANUFACTURING SOLUTIONS
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BPCs are single-use, flexible container systems commonly used for critical liquid-handling applications in the biopharmaceutical industry.
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ASEPTICARE offers a versatile, closed aseptic environment, ideal for aseptic and aseptic-toxic operations. It ensures contamination control and improves operational efficiency across various sterile processes.
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Freeze dryer processes for pharmaceutical products require robust equipment and quality designs. Dec offers automated solutions for loading and unloading lyophilization systems. With our modular design approach and in-depth knowledge on this type of systems, we offer fixed or flexible loading solutions for any lyophilizer.
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Used Capmatic inline vial filling line, model Conquest FS8 consisting of: 36" Capmatic accumulation table, serial# TT01110917: Model Conquest FS8 Capmatic inline filler, (16) head walking beam filling station with (8) piston fill pumps, integrated chain conveyor and rotary stopper feed system with vibrating bowl feeder, Allen Bradly Panelview 1000 HMI, serial# CQ1110919, built 2002: Model R-R Pharma Capmatic crimp capper, type RoadRunner, (12) station with Capmatic cap elevator, Allen Bradley PLC controls and Panelveiw 900 HMI, serial# RR00030718, built 2003: Capmatic dual position tray loader, serial# TT02020846, built 2002.
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AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.