INSIGHTS ON LIQUID DOSE MANUFACTURING

  • From Batch, To Continuous Chemistry, To Continuous Processing

    Explore how understanding the transport phenomenon in the boundary layer can allow us to engineer the flow to manage the rate-limiting step and intensify the process.

  • Key Topics And Trends In Aseptic Filling

    Aseptic filling is vital yet often guided by outdated practices. Discover expert insights on modern technologies, evolving regulations, and data-driven strategies to improve compliance and reduce risk in this critical manufacturing step.

  • Bulk Filling Of Drug Substance | Accurate Aliquoting

    Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.

  • A Standardized Gloveless Robotic Isolator

    By eliminating human intervention—the primary risk factor compromising drug sterility and quality—gloveless aseptic processing technology offers manufacturers greater flexibility, safety, and regulatory compliance in their filling operations.

LIQUID DOSE MANUFACTURING SOLUTIONS

  • Used 10 sq meter (107 sq ft) Telstar Freeze Dryer, model Lyomega 100GN2, stainless steel construction, front loading/unloading with access door, with (10) 90 cm wide x 120 cm deep usable shelves, (11) total shelves, external condensor, stoppering with top mounted hydraulic ran with pump, refrigeration and vacuum skid with Cumulus PX20 refrigeration package, (2) 2.2 kw Telstar vacuum pumps with (1) 1.7 kw Aerzen booster pump, integrated control panel with Allen Bradley SLC 5/05 PLC controller, and external hmi control, serial# 231796. Built 2006.

  • Dec’s ability to provide end-to-end solutions from API manufacturing to primary packaging filling covers the complete range from R&D processes and small batches to large filling campaigns. Our solutions include state of the art robotics for the filling and handling of complex delivery systems like pre-filled syringes (PFS).

  • Our comprehensive inspection systems, designed to adhere to the strictest regulatory standards, offer robust quality assurance, safeguarding the integrity of your product from development through to market.

  • For highly accurate and controlled filling and weighing of sterile liquids, our proven and reliable technology prevents costly overfilling. The easy to validate aseptic filling machines are compatible with all high-tech production facility equipment, software and processes known in the pharmaceutical primary packaging industry.

  • The Isolator Glove Testing System enables for Annex 1 compliant wireless and tubeless leak testing of gloves installed in Isolators or RABS. The GTS with the latest software technology offers an extremely flexible and fully integrable solution for glove testing as part of glove management.