INSIGHTS ON LIQUID DOSE MANUFACTURING

  • Meet Regulation Requirements With RTU Vials And Cartridges
    10/9/2025

    Sterile manufacturing remains vital, with resilient supply chains preventing shortages. Industry and regulators prioritize integrity as demand surges, making it the fastest-growing pharmaceutical segment.

  • Enhancing Aseptic Fill-Finish Processes
    7/3/2025

    Achieve exceptional product recovery and sterility. Learn about high-integrity surge bags, advanced leak detection, and flexible design options for your fill-finish applications.

  • Spray Dried Biologics For Injectable Dosage Forms
    5/15/2026

    Spray drying enables scalable production of stable, high‑concentration biologics as sterile powders, improving delivery, reducing costs, and overcoming limitations of traditional freeze‑drying methods.

  • Inline Buffer Formulation Systems
    7/6/2026

    Eliminate large storage tanks and optimize cleanroom space with automated inline buffer formulation. See how on-demand fluid handling provides precise, real-time pH and conductivity control.

  • Digital Twin For Fill-Finish: Overview And Use Cases
    3/16/2026

    Digital twin technology optimizes aseptic fill-finish through real-time mirroring and predictive simulation. Improve yields and validate complex recipes by integrating dynamic virtual models.

LIQUID DOSE MANUFACTURING SOLUTIONS

  • AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.

  • A gloveless system that reduces risk for flexible vial, syringe, and cartridge filling.

  • Roller compaction is a proven process providing a method of granulation for materials that are known to be sensitive to heat and/or moisture.

  • Our Rigid Stainless Steel Containment Isolators have been designed for handling potent compounds that can offer guaranteed levels of operator protection as low as 10ng/m3 (task duration). These include designs for sampling, dispensing and sub-division, mixing, milling and vessel charging, as well as containing integrated process devices such as filter dryer units, tablet press enclosures, blenders, mills and pack off systems.

  • Dec’s ability to provide end-to-end solutions from API manufacturing to primary packaging filling covers the complete range from R&D processes and small batches to large filling campaigns. Our solutions include state of the art robotics for the filling and handling of complex delivery systems like pre-filled syringes (PFS).