INSIGHTS ON LIQUID DOSE MANUFACTURING

• The Challenges Batch And Continuous Manufacturing Bring To Containment Product Design

  Methods and techniques used in pharmaceutical manufacturing are broadly reviewed. There are two basic models of pharma manufacturing: batch and continuous. Both approaches are defined. It is concluded that both approaches have elements of the other. Generally speaking, many pharma manufacturing procedures are transitioning from the batch to the continuous approach.

• Sterile Production Process Studies Using 100% Headspace Inspection Of Finished Product

  This app note describes the application of the PULSAR inspection platform to perform 100% headspace oxygen monitoring during the filling of oxygen-sensitive formulations, 100% container closure inspection of suspect batches, moisture inspection of freeze dried product, and automated media fill inspection.

• Container Closure Integrity Testing Method Development

  Recent regulatory revisions have also put emphasis on robust method validation for container closure Integrity test methods. This webinar covers approaches that can be used for method development for CCI testing in all phases of the product life cycle.

• HPAPI Processing And Drying Suite For Operator And Product Protection

  A two-part enclosure consisting of a single pass air flow glove box enclosure and a nitrogen purge enclosure was designed to provide protection to the operator and product.

• Using Positive Controls In Container Closure Integrity Studies

  This webinar describes the use of positive controls as an important element of CCI studies designed to validate packaging components for CCI or to qualify processes for producing good CCI.

• Venting Fume Hood Base Cabinets — A Better Way

  Frequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out. 

• Selection Criteria for Ribbon, Vertical, or Tumble Blenders

  Among solid-solid blending systems, the three most common types are the horizontal ribbon blender, the cone screw vertical blender and the tumble blender. Aside from level of shear or ‘gentleness’, other factors help determine which type of blender will work most efficiently in a certain application. Following are some things to consider when choosing your blender.

• 8 Key Factors When Selecting A Powered Air-Purifying Respirator System

  This white paper explores eight considerations in detail and could be helpful to EHS managers and supervisors looking to select a Powered Air-Purifying Respirator system for their particular application.

• How The Extrusion Process Impacts The Quality Of Blow/Fill/Seal Products

  A collaborative study involving Cardinal Health, Inc. and Air Dispersions Ltd. has been carried out to further the understanding of the extrusion process and its impact upon the quality of Blow/Fill/Seal product.