INSIGHTS ON SOLID DOSE MANUFACTURING
-
Isolators For Pharmacy Compounding – Time For Change?
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
-
Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
-
Solubility Enhancement Via Amorphous Solid Dispersions
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
-
How Is Peptide Crystallization Screening Used In Peptide-Based Therapeutic Development?
Hannah McLachlan, Project Scientist IV at Cambrex Edinburgh, on what crystallization screening delivers for peptide therapeutics — more stable material, higher purity, and a molecule clients can store without specialist infrastructure.
-
Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion2/27/2025
Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
-
Optimizing Yield, Purity, And Scalability In A Cost-Effective Manner During Process Development7/23/2026
Daniele Vigo, Assistant Director at Cambrex Milan, on getting yield, purity, and scalability right without burning through the budget.
-
Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies7/15/2026
In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
-
Combining Patient Centricity And Commercial Viability In Pediatric Product Development8/15/2024
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
-
The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Establish safe barrier protection in minutes with a portable benchtop isolator. Secure containment for hazardous materials or inert gas processing across flexible laboratory scales.
-
AST’s line of table-top machines, GENiSYS® Lab, are ideal systems for drug product development and cGMP production applications. Each system is designed to automate the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. These table-top systems are engineered to have complete compatibility with cleanroom environments, including Laminar Air Flow Hoods, Bio-Safety Cabinets and aseptic isolators.
-
Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.
-
Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.
-
Providing customized solid-dose bottling solutions with agile production for a wide range of bottle sizes and shapes, flexible quantity requirements, and multiple cap types.