Solid Dose Manufacturing

INSIGHTS ON SOLID DOSE MANUFACTURING

5 Hidden Risks In Early-Phase OSD Formulation Development
Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
Why Spray Drying Is Gaining Attention
Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.
When To Consider Material And Personnel Airlocks For Downflow Booths
Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.
Navigating High-Potency OSD Manufacturing
Learn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.

The Importance Of Polymorph Screenings
5/6/2026

Discover how systematic polymorph screening reduces development risk, safeguards product performance, and enables confident solid‑form selection across the drug development lifecycle.
Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability
7/15/2026

Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.
Accelerating An Innovative High Potency Oncology Therapy To Market
5/13/2026

Learn how disciplined containment, proactive risk management, and collaboration accelerate complex oncology programs under tight timelines while protecting quality, safety, and global launch readiness.
Inline Buffer Formulation Systems
7/6/2026

Eliminate large storage tanks and optimize cleanroom space with automated inline buffer formulation. See how on-demand fluid handling provides precise, real-time pH and conductivity control.
Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets
1/27/2025

Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.

Containment: Granulator Technology

Used for lab scale and production operations at multiple International Pharma manufacturers, our Granulator containment technology applications take the idea of retrofits to another level.
Leaders In Oral Formulation

Mikart’s development services include a range of pre-formulation capabilities for both oral solid and non-sterile oral liquid dose drug products.
Technology Transfer And Commercial Manufacturing Of Tablets And Capsules

Finding a strategic CDMO partner that will offer tailored solutions for your late phase clinical and commercial needs, mitigate risks, and bolster your supply chain is crucial for meeting project milestones on time.
Nutritional Tablet Manufacturing Equipment

Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.
Solid Form Services

We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.