INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Bausch + Strobel SP-100 Powder filling Machine with control cabinet, stainless steel construction, with filler funnels and auger, serial# 51181, built 1998.

  • Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

  • Combination Powder and Fume Hood with HEPA filtration and house exhaust connection designed to process liquid and powder substances. Fume Hood designed to house stir plate and analytical balance. It features cup sink; air, water, and gas fittings; and alarm for monitoring and maintaining recommended face velocity of 75 LFPM. Fume and Powder Hoods separated by sliding door to eliminate cross-contamination during processing. Powder Hood uses front airfoils and rear plenums to maintain laminar airflow across the work surface, which is vented through a HEPA filtration system to house exhaust.

  • Over many years, Dec has acquired recognized expertise in designing and supplying an extensive range of isolators enclosing a mill or a MC DecJet® spiral jet mill for either individual or combined operation.

  • The pharmaceutical industry has steadily moved to increased production and handling of sterile highly potent active ingredients (HPAPIs). Dec’s containment technologies comply with pharmaceutical quality manufacturing standards and are available for aseptic operations.