INSIGHTS ON SOLID DOSE MANUFACTURING
-
Barrel-Style vs. Standard Dust Cups vs. Bellows: The Essentials Behind Producing The Highest Quality Tablets Free From Contaminates
Dust cups and bellows are essential components in tablet manufacturing, utilized to prevent lubricants from contaminating the tablets.
-
Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?
What is head pressure in your hopper and how does it relate to tablet press performance?
-
Functional Release Multiparticulates Slam
Review Adare Pharma Solutions’ innovative technologies and learn how these capabilities can improve patient outcomes and improve manufacturing efficiency.
-
Isolators For Pharmacy Compounding – Time For Change?
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
-
Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design11/11/2024
The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.
-
5 Advancements In Tablet Compression That Pharma Can't Ignore In 202611/4/2025
New materials, smart automation, and in-press quality control are optimizing tablet compression. These five key innovations are driving efficiency and consistency in solid dose manufacturing today.
-
Softgel Formulation: Addressing Stability, Shelf-Life, And Bioavailability5/16/2024
A CDMO that has expertise and resources in softgel formulation can help companies address stability issues, improve drug bioavailability, or ensure compliance with regulations.
-
Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets1/27/2025
Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.
-
A Solvent-Free, Fusion-Based ASD Manufacturing Process3/5/2024
Explore a solvent-free alternative for the production of amorphous solid dispersions (ASDs) that not only improves manufacturability but also reduces the carbon footprint of ASD manufacturing.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.
Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.
-
Explore an encapsulator with accurate operation for orientation, separating, filling, closing, and ejecting capsules along with sensors to control powder, pellets, and capsules.
-
Used Sejong rotary tablet press, model GRC-15C, 15 station, D tooled, 6 kn main compression, 2 kn pre compression, 25 mm max tablet diameter, 22 mm max depth of fill, with feed hoppers, rated up to 67500 tablets/hour, with integrated controls and touchscreen interface, serial# ST17866, built 2017.
-
Used A Berents BECOMIX planetary mixer, model RW 30, stainless steel construction, 60 liter total capacity, 30 liter working capacity, chamber rated -1/2 bar(-14.5/29 psi) at 134 c internal, jacketed for 4 bar(58 psi) at 152 c, top mounted variable speed agitator with side wall scrappers, bottom mounted homogenzier, dome top with lift/lower mechanism, cone bottom, with on board controls and external control panel, 3/50/400 volt, Fabr# 011/1-586, built 1996.
-
The production and handling of highly potent sterile APIs within a multi-purpose designed plant are becoming more and more prevalent within the pharmaceutical industry.