INSIGHTS ON SOLID DOSE MANUFACTURING
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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Patient Adherence With A Novel Dosage Form
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Smart Softgels: Driving Innovation In Pharma
Learn about how softgels are poised to facilitate innovation in the pharmaceutical industry as well as ongoing advancements in optimizing drug bioavailability through nano formulations.
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How To Address Your Solid Dosage Processing Needs
Unlock the keys to consistent solid dosage products. Learn to align unique product needs with optimal processing requirements and equipment strategies. Gain a roadmap for improved quality and reproducibility.
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Cytiva's Aseptic Filling Workcell User Group1/9/2026
Discover how global collaboration among aseptic filling experts is driving innovation and improving operations.
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Fundamentals Of Power Blending Simulations2/26/2025
Predicting blending quality doesn't have to be a guessing game. Learn how to leverage virtual prototypes to make informed decisions and minimize costly trial-and-error in tablet manufacturing.
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The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators12/27/2024
Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.
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A Technology Driven CDMO & Trusted Manufacturing Partner7/18/2024
Whether it's through extended release formulations or titratable dosage forms, we are dedicated to addressing the specific needs of different patient populations, including pediatrics and geriatrics.
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Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership In Navigating A Paragraph IV ANDA Submission6/26/2024
The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.
SOLID DOSE MANUFACTURING SOLUTIONS
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.
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Each service visit will include the following:
- Preventative Maintenance
- Equipment inspection (paddle feeder, tachometer, cams, compression rollers, etc.)
- Turret inspection
- Additional Operator and Technician Training
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Used Fitzpatrick Chilsonator roller compactor, model 1.5LX8D, with 8" diameter x 1.5" wide grooved rolls, vertical and horizontal pre-compression screws, serial# 489.
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Used BellatRx electronic lane counter, model RX-Fill PLUS, speeds up to 25 bottles/minute at 100 count, 2-40mm tablet size, 1" - 4" by 12" high bottle size, 0.5" or larger neck diameter, Allen Bradley PLC controls with PanelView 600 HMI, 120 volt, order# 7155, serial# 035, built 2019.