INSIGHTS ON SOLID DOSE MANUFACTURING

• Manufacturer Finds Solution For Transporting HPAPI Product with Containment

  A client was in need of a containment enclosure for an analytical weighing and solution-preparation operation involving Highly Potent Active Pharmaceutical Ingredients (HPAPI) in powder form. Their goal was to transfer product from an enclosure to another enclosure. read how Flow Sciences used a recently developed containment device and augmented to fit the specific needs of the client.

• 10 Worst Containment Engineering Mistakes

  Engineering is a process to develop a design to solve a problem. In the world of containment engineering, careful premeditation is important to the completion of a successful engineering project.

• Determination Of Moisture Permeation During Product Shelf Life

  How non-destructive headspace analysis information can be critical for QC groups performing stability studies, or for packaging development groups responsible for choosing the optimal packaging.

• Fluid Bed Granulation And Melt Granulation In Pharma Manufacturing

  Affording superior reproducibility and control than other granulation techniques, fluid bed granulation and melt granulation can be tightly regulated to produce uniform material with a specified particle size.

• Evaluating A Chemical Fume Hood For Containment Of Solids, Liquids, And Vapors Using ASHRAE 110, HAM, And ISPE Methods

  Originally designed around 350 years ago to contain accidents and prevent bad odors in the laboratory, the fume hood has become a device that can routinely produce control levels of vapors down to the part-per-billion level. In this study, Flow Sciences chose to meld existing techniques centered around ASHRAE 110 with widely-accepted particulate containment measurement techniques. The Flow Sciences fume hood, when used in conjunction with good lab practices, is capable of providing workers with the protection they need for applications using solids, liquids and gases.

• Reducing Risks In Tablet Presses And Tooling With Effective Cleaning

  With properly cleaned and maintained tooling, tablet manufacturers can expect the highest quality of tablets and a longer production life from their tooling. 

• Shipping, Assembling, And Installing Bulky Exhaust Equipment In A Lab

  Though delivering, unloading, staging, and assembling are required steps in all lab construction, there are design aspects of lab equipment that can contribute to its successful field installation.

• A Proven, Cost-Effective, Single-Use Powder Transfer Solution

  Single-use transfer technology has been used in biopharma manufacturing for years. However, upstream powder-handling processes haven’t been improved upon. Now, the industry is seeing a need for better ways to bring powders to the hydration process and begin upstream biologic manufacturing.

• Managing Risks With Potent Pharmaceutical Products

  Managing the risks associated with potent compounds requires a knowledgeable team as well as the design and implementation of an effective safety program.