INSIGHTS ON SOLID DOSE MANUFACTURING

• Predicting Drug-Loading Limits In Tablet Formulations

  Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

• HPAPIS Production: "Where Micrograms Matters"

  In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.

• Delivering API-In-Capsule For Potent, Low-Flow Compounds

  See how an automated capsule-filling approach addressed poor-flow APIs, improved operator safety, and supported fast scale-up for clinical supply needs.

• The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators

  Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.

• Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing

  6/30/2025

  Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.

• Single-Use Containment And Oral Solid Dosage (OSD)

  9/16/2026

  Flexible single-use containment systems achieve sub-microgram exposure levels while eliminating cleaning validation downtime for high-potency oral solid dose manufacturing.

• HPAPI Containment: A Full Lifecycle Safety Innovation

  6/15/2026

  Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.

• Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability

  7/15/2026

  Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.

• Paediatric Drug Product Development Through To Commercialisation

  9/3/2026

  Learn how an innovative pediatric minitablet achieved patient-friendly administration, precise dosing and scalable manufacturing to support a smooth path to market.