INSIGHTS ON SOLID DOSE MANUFACTURING
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When To Consider Material And Personnel Airlocks For Downflow Booths
Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.
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Exploring The Future Of Tablet Compression Across Emerging Industries
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Improving API Solubility Using Hot Melt Extrusion Formulation
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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Liquid Suspension Trends In The CDMO Space
Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
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Achieving Manufacturing Efficiency In OSD Manufacturing10/16/2024
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators12/27/2024
Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.
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Segments: Next-Generation Tablet Press Technology10/7/2025
Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
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A Powerful Non-Destructive Tool For Tablet Characterization10/6/2025
Discover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
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Round Tablet Compression Tooling — To Key Or Not To Key The Punches7/30/2024
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
SOLID DOSE MANUFACTURING SOLUTIONS
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Powder in a bottle is used to accelerate formulation development and introduce new chemical entities into Phase I clinical trials.
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Each service visit will include the following:
- Preventative Maintenance
- Equipment inspection (paddle feeder, tachometer, cams, compression rollers, etc.)
- Turret inspection
- Additional Operator and Technician Training
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Mikart’s development services include a range of pre-formulation capabilities for both oral solid and non-sterile oral liquid dose drug products.
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Ensure operator safety and product purity with unidirectional airflow solutions. Explore how modular ISO 5 environments provide containment and cross-contamination control for critical processes.