INSIGHTS ON SOLID DOSE MANUFACTURING
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![3P innovation - achieving licensing]( "Achieving Licensing For A Healthcare Solution")
Achieving Licensing For A Healthcare SolutionFacing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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![Natoli - Fundamentals Of Power Blending Simulations]( "Fundamentals Of Power Blending Simulations")
Fundamentals Of Power Blending SimulationsPredicting blending quality doesn't have to be a guessing game. Learn how to leverage virtual prototypes to make informed decisions and minimize costly trial-and-error in tablet manufacturing.
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![GettyImages-2002525379-production-solid-dose-capsules]( "Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion")
Shaping The Future Of Solid Dose Manufacturing With Hot Melt ExtrusionEnhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
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![GettyImages-1140632275-tablet-bottle-manufacturing]( "Advancements In Tablet Compression Tooling: What Manufacturers Need To Know")
Advancements In Tablet Compression Tooling: What Manufacturers Need To KnowDiscover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges2/3/2025
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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When To Consider Material And Personnel Airlocks For Downflow Booths3/20/2026
Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.
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Safely Scaling High Potency API Manufacturing4/13/2026
Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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Developing And Manufacturing Minitablets To Extend Drug Lifecycle1/27/2025
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
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Contract Pharma 2026: Mikart On CDMO Collaboration4/30/2026
An overview of a milestone pharmaceutical outsourcing conference focused on CDMO collaboration, tech transfer, and oral solid and liquid dose manufacturing strategies.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Esco - DFB still]( "Engineered Unidirectional Airflow For Reliable And Continuous Safety")
High-efficiency filtration and controlled airflow maintain a clean workspace, preventing cross-contamination and ensuring reliable containment across diverse industrial and laboratory applications.
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![flexiblecontainmentisolators]( "Flexible Containment Isolators")
Flexible Containment Isolators provide containment standards better than can be achieved with Downflow Booth technology, and often compare favorably with a Rigid Isolator system.
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![Powder Rheology Feature]( "Powder Rheology Accessory")
The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
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![ILC Dover - Containment Solutions]( "High-Containment Solutions For HPAPI Handling")
Handling highly potent active pharmaceutical ingredients calls for containment systems that protect operators while maintaining strict OEL thresholds below 0.1 μg/M3 throughout every transfer step.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
