INSIGHTS ON SOLID DOSE MANUFACTURING
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The Art And Science Of Pre-Picking Tablet Designs
Picking and sticking are the most common tablet defects that can reduce your product quality and performance. This makes perfecting the right pre-picking strategy essential to improving your processes.
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A Technology Driven CDMO & Trusted Manufacturing Partner
Whether it's through extended release formulations or titratable dosage forms, we are dedicated to addressing the specific needs of different patient populations, including pediatrics and geriatrics.
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Low-Bioburden Powders For Terminal Sterilisation
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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Round Tablet Compression Tooling — To Key Or Not To Key The Punches7/30/2024
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden3/12/2025
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
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Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion2/27/2025
Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Solubility Enhancement Via Amorphous Solid Dispersions2/27/2025
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
SOLID DOSE MANUFACTURING SOLUTIONS
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Each service visit will include the following:
- Preventative Maintenance
- Equipment inspection (paddle feeder, tachometer, cams, compression rollers, etc.)
- Turret inspection
- Additional Operator and Technician Training
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Master the art of tablet manufacturing with our comprehensive hands-on seminar, designed to equip you with in-depth knowledge and skills required for pharmaceutical and supplement manufacturing. This two and a half-day course covers essential topics such as tablet press setup, powder preparation, formulation, excipients, API, direct compression, wet granulation, dry granulation, tablet press operation, compaction, lubricants, and quality control.
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Used Shionogi Qualicaps capsule checkweigher, model CWI-40, nominally rated up to 40000 capsules/hour throughput, with weigh check option, capsule reject system, stainless steel feed hopper, includes size 00, 0, 1, 2, 3, and 4 change parts with HMI touchscreen, serial# S0053, built 2004.
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Used Freund-Vector TFC-220 Pilot Scale Roll Compactor/Granulator, stainless steel construction, 20g - 20kg/hour capacity, with 200mm diameter x 20mm roll face rolls, grooved rolls, product hopper with integrated tapers de-aeration screw, with bottom mill, operator HMI touch screen, 230 volt, serial# RC-330, built 2012.
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Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.