INSIGHTS ON SOLID DOSE MANUFACTURING

• Predicting Softgel Stability And Shelf Life Using Accelerated Modeling

  Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

• Developing And Manufacturing Drugs With HPAPIs

  Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.

• Segments: Next-Generation Tablet Press Technology

  Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.

• Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies

  In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.

• Compaction Simulation For Tablet Technology Transfer And Scale-Up

  7/15/2026

  Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.

• Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up

  9/9/2026

  SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.

• Rational Design And Material-sparing Strategies For Enabled Intermediates And Drug Products

  9/9/2026

  A material-sparing strategy integrating formulation mapping, lab-scale spray drying, and compact screening can accelerate risk identification and inform first-round tablet formulation decisions for poorly soluble APIs.

• Pharmaceutical X-Ray Counts Capsules And Pills

  8/15/2025

  See how advanced x-ray inspection technology verifies correct pill count, identifies broken capsules, and detects foreign contaminants in pharmaceutical sachet packets.

• De-Risking Production Of Complex Oral Solid Dosages: Considerations & Key Capabilities

  7/13/2026

  Reduce formulation and scale-up risk with integrated development and manufacturing expertise for complex OSD products.