INSIGHTS ON SOLID DOSE MANUFACTURING
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![Solubility And Improved Patient Outcomes-GettyImages-2277363545]( "Solubility And Improved Patient Outcomes")
Solubility And Improved Patient OutcomesPoor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
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![adare ceo interview]( "The Future Of Oral Solid Dose Development And Innovation")
The Future Of Oral Solid Dose Development And InnovationTom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
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![Medicine, pills-GettyImages-186846700]( "Delivering API-In-Capsule For Potent, Low-Flow Compounds")
Delivering API-In-Capsule For Potent, Low-Flow CompoundsSee how an automated capsule-filling approach addressed poor-flow APIs, improved operator safety, and supported fast scale-up for clinical supply needs.
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![Pediatrics iStock-1223445550]( "How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions")
How To Solve Complex Pediatric Dosing Challenges Using Tailored SolutionsWith a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation8/20/2026
Explore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.
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Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months2/26/2026
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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Harnessing Digital Twins To Optimize Tablet Manufacturing10/30/2025
Unlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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Developing And Manufacturing Drugs With HPAPIs1/27/2025
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design11/11/2024
The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Quick-Release Pharmaceutical Tablet Tooling]( "Quick-Release Pharmaceutical Tablet Tooling")
Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.
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![Pharma-Drum]( "Pharmaceutical Drum Containment Systems")
The patented DCS® pharmaceutical Drum Containment System is a stainless steel cylindrical glove box with a glass cover and two glove ports. Highly economical in comparison with conventional isolation systems, DCS® ensures precise, contamination free emptying of drums providing high containment (< 1 µg/m3).
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![GettyImages-669121480-pill-tablet-capsule-OSD-oral-solid]( "Oral Solid Dose Formulation Assessment Services")
Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.
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![Pharma containment isolators]( "Pharmaceutical Containment Isolators")
Our Rigid Stainless Steel Containment Isolators have been designed for handling potent compounds that can offer guaranteed levels of operator protection as low as 10ng/m3 (task duration). These include designs for sampling, dispensing and sub-division, mixing, milling and vessel charging, as well as containing integrated process devices such as filter dryer units, tablet press enclosures, blenders, mills and pack off systems.
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![GettyImages-1405590436-lab-perfusion-cleanroom]( "Small Molecule Drug Substance: API Capabilities")
Eurofins CDMO Alphora handles small molecule APIs and HPAPIs from IND-enabling through commercialization, with FDA and Health Canada-approved facilities scaling up to 125 kg per batch. Contact them to discuss your program.
