INSIGHTS ON SOLID DOSE MANUFACTURING

• Benefits Of Single-Use Isolators For Cytotoxic Payload Handling

  Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.

• Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives

  A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.

• Solubility Enhancement Via Amorphous Solid Dispersions

  Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.

• Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design

  The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.

• High Potency APIs And The Evolving Demands Of Drug Development

  4/13/2026

  See how higher API activity is changing expectations around containment, scalability, and cross‑functional alignment — and why early decisions now have a greater impact on long‑term success.

• Patient Adherence With A Novel Dosage Form

  11/13/2025

  A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.

• Lower Punch Tip Bending / Buckling

  11/11/2024

  When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

• Cytiva's Aseptic Filling Workcell User Group

  1/9/2026

  Discover how global collaboration among aseptic filling experts is driving innovation and improving operations.

• The Future Of Sustainable Amorphous Dispersion Development

  4/15/2026

  Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.