INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-488719432-bilayer-tablet-OSD-oral-solid]( "Customized Release Through Dispersed Dosage Formats")
Customized Release Through Dispersed Dosage FormatsTypically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
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![Cytiva's Aseptic Filling Workcell User Group]( "Cytiva's Aseptic Filling Workcell User Group")
Cytiva's Aseptic Filling Workcell User GroupDiscover how global collaboration among aseptic filling experts is driving innovation and improving operations.
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![Adare-2]( "Layer By Layer: 3D Screen Printing And The Future Of Drug Development")
Layer By Layer: 3D Screen Printing And The Future Of Drug Development3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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![GettyImages-2086161977-blister-packaging-liquid-medical-medicine]( "The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric Solutions")
The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric SolutionsPharmaceutical packaging must evolve alongside drug development to ensure stability, safety, and regulatory adherence, utilizing innovative designs to improve therapeutic outcomes and patient accessibility.
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Automated Precision Powder Filling For Annex 11/21/2026
Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.
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HPAPIS Production: "Where Micrograms Matters"4/13/2026
In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.
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Blending And Simulation: A Beginner's Guide2/26/2025
This beginner-friendly webinar reveals essential steps to understand mixing, reduce segregation, enhance efficiency, and improve product quality with granular materials.
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How To Fast-Track Your Oral Solid Dose To Phase 12/17/2026
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Low-Bioburden Powders For Terminal Sterilisation2/24/2026
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Used Korsch XL 400 2-Layer Tablet Press]( "Used Korsch XL 400 2-Layer Tablet Press, 35/29 Station")
Used Korsch XL 400 2-Layer rotary tablet press. 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.
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![Cozzoli Powder Filler]( "Used Cozzoli Pharmaceutical Powder Filling System: PF2-IS-176")
Used Cozzoli powder filler, model PF2-IS-176, stainless steel construction, incomplete unit, Allen-Bradley PLC with touchscreen interface, 115 volts, portable on casters, built 2019. As Is.
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![Aseptic-Pharmaceutical-Isolators-from-Franz-Ziel]( "Aseptic Pharmaceutical Isolators From Franz Ziel")
Isolators with product protection as a housing for aseptic processes, e.g., filling, loading and unloading of freeze dryers.
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![Esco-Pharmcon Downflow Booth Gen 2 (DFBG2)]( "Customizable Downflow Booths")
Ensure operator safety and product purity with unidirectional airflow solutions. Explore how modular ISO 5 environments provide containment and cross-contamination control for critical processes.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
