• With over 100 years of experience in feeding technology, Coperion K-Tron development and engineering teams have created smart feeding solutions. Without consistent, dependable feeder accuracy and repeatability for your process, the integrity of any recipe—and hence the final product—will be compromised. 

  • Natoli Engineering Company, through its Carlisle Precision Encapsulation Parts subsidiary, manufactures premium change and spare parts for many brands of encapsulation machines.

  • Superior accuracy gain-in-weight and loss-in-weight batch weighing of final blends, excipients and active pharmaceutical ingredients.

  • The ChemoSphere is a safe, clean, cost-effective C.A.C.I. for chemo compounding that is USP <797 / 800>, OSHA, AND NIOSH compliant.

  • Basic Powder Flow Characterization [USP <1174>]:

    A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.

    Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.

    When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.