INSIGHTS ON SOLID DOSE MANUFACTURING
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The Future Of Oral Solid Dose Development And Innovation
Tom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
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Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying
Although well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.
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Overload Setting – Tricks And Techniques
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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Harnessing Digital Twins To Optimize Tablet Manufacturing10/30/2025
Unlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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Optimising Solubility: Selecting The Right Technology For Early Drug Development5/6/2026
Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.
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Solvent-Free, Fusion-Based Amorphic Dispersion Process7/11/2024
Discover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden3/12/2025
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
SOLID DOSE MANUFACTURING SOLUTIONS
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The patented DCS® pharmaceutical Drum Containment System is a stainless steel cylindrical glove box with a glass cover and two glove ports. Highly economical in comparison with conventional isolation systems, DCS® ensures precise, contamination free emptying of drums providing high containment (< 1 µg/m3).
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Dec provides unique solutions to charge process equipment such as reactors, mixing vessels or dryers in a fully safe manner eliminating the need to connect the isolator directly to the equipment to be charged or to install the isolator on an upper floor. A single isolator system can be used for multiple vessels charging.
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Our Rigid Stainless Steel Containment Isolators have been designed for handling potent compounds that can offer guaranteed levels of operator protection as low as 10ng/m3 (task duration). These include designs for sampling, dispensing and sub-division, mixing, milling and vessel charging, as well as containing integrated process devices such as filter dryer units, tablet press enclosures, blenders, mills and pack off systems.
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Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
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Used Powrex high shear mixer, model FM-VG-25, stainless steel construction, 15 liter working capacity with high speed chopper driven by 1.5 kw motor, main shaft driven by 3.7 kw motor, with controls, serial# 903222, built 1990.