INSIGHTS ON SOLID DOSE MANUFACTURING

  • Safely Scaling High Potency API Manufacturing
    4/13/2026

    Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.

  • Benefits Of Single-Use Isolators For Cytotoxic Payload Handling
    6/15/2026

    Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.

  • Blister Solutions
    3/4/2025

    With over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.

  • Bottling Solutions
    3/4/2025

    Explore a bottling solution that is meticulously engineered to adhere to the most stringent pharmaceutical standards, which guarantees that each product is crafted with unparalleled quality and precision.

  • The Art And Science Of Pre-Picking Tablet Designs
    7/30/2024

    Picking and sticking are the most common tablet defects that can reduce your product quality and performance. This makes perfecting the right pre-picking strategy essential to improving your processes.

SOLID DOSE MANUFACTURING SOLUTIONS

  • At Natoli, we know that quality is paramount. Our cutting‐edge Precision CT Scan Service is designed to detect even the subtlest imperfections in tablets, ensuring you achieve the highest standards of quality every time.

  • With our pharmaceutical tablet manufacturing capabilities, we can take your product from formulation development through full-scale commercial production.

  • Our HPAPI development and manufacturing spans preclinical through commercial supply across 13 global sites, with SafeBridge-certified containment and 30 years of cytotoxic compound expertise.

  • Unused Fluid Air 300 liter fluid bed dryer, model 300, 316 stainless steel contact parts, 304 non product contact, includes tower, filter system, explosion suppression system, product bowl with automatic side discharge, hydraulic bowl lifting system, spray nozzles (for possible conversion to top spray granulation), HMI and machine controls, valves, and other associated parts, serial# 10440, built 2014.

  • Used 79 gallon (300 liter) Inox reactor, stainless steel construction, approximately 24" diameter x 34" straight side, dish lid top with dish bottom, jacket and interior rated 30 psi and full vacuum at 300 F, 6" top access, with (1) 4", (1) 3", (2) 2" and (2) 1.5" nozzles on top, with bottom entering magnetic agitator, .75 hp with controls, 1.5" center bottom outlet, with load cells, all on portable frame, serial# 95011-2, CRN# K82555, built 1995.