INSIGHTS ON SOLID DOSE MANUFACTURING
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The Importance Of Automation For API Manufacturing: Bulk Handling, Dispensing, IBC Filling
An operation required manual filling of IBCs by using a flexible isolator installed on an upper floor with large amounts of excipients (lactose and micro cellulose)> 100 kg and only a small amount of APls of a few kilos. Operation was strenuous due to the large quantity of excipients to be handled in the isolator which lead to the damage of the flexible isolator and containment breach. Several equipment and process changes allowed them to see an increase of plant productivity.
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Selecting Sterile API Transfer Technologies
A CDMO was looking to solve the issue of charging sterile drug substance into a mixing tank which is a widespread problem in aseptic processing and particularly in formulation.
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Fill-Finish Equipment For Pharma Production: SP i-Dositecno 50 VPM Isolated Line With Freeze Drying Automated
The SP i-Dositecno 40 vial per minute line under isolation for liquid and freeze-dried products (RTU components).
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Drug Product Advancement: A Path Through Development By Powder-In-Capsule Approach
Review best practices PIC and PIB challenges and rapid encapsulation transfer from clinic to commercial scale in these webinar slides.
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Product Development For Oral Solid Dose Using Continuous Manufacturing10/30/2020
A thorough evaluation using several small-scale studies should be completed to help determine whether continuous or batch manufacturing is the best fit for your product.
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Integration Of Milling, Blending, And IBC Handling Systems For API Production9/1/2020
A multipurpose facility for API production had various requirements including milling, micronizing, packaging, and the possibility to blend various batches together before or after milling.
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Creating A Biosafety Cabinet Training Program3/15/2022
This article provides information for creating your Biological Safety Cabinet (BSC) training program, a list of resources and videos, and how your BSC manufacturer could provide additional resources.
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Evaluating Your Research Equipment's Cost of Ownership3/22/2022
In this paper we review how lifespan, reliability, technical support, maintenance costs and workflow efficiency factor in to calculating the cost of ownership of your research equipment.
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Dec Group Contained Powder Handling Systems9/2/2020
Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.- Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.
SOLID DOSE MANUFACTURING SOLUTIONS
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Over many years, Dec has acquired recognized expertise in designing and supplying an extensive range of isolators enclosing a mill or a MC DecJet® spiral jet mill for either individual or combined operation.
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The Coperion K-Tron Microfeeder for low rate powder feeding includes design options for handling toxic powders as well as difficult flowing materials.
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Used 150 cu ft Patterson Kelley double cone blender, 316L stainless steel product contact surfaces, approximately 95" diameter, rated 62#/cu ft maximum material density, on stainless steel stands with 20 hp motor drive giving approximately 1.4 - 8.6 rpm shell rotation speed, 18" feed opening, 10" discharge opening, on 304 stainless steel stands with approximately 25" discharge height, approximately 144" overall installed height, approximately 124" swing radius, serial# BC65251, built 2013.
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The Coperion K-Tron PH line of pharmaceutical design loss-in-weight vibratory tray feeders combine high accuracy with a configuration which is ideal for metering of uncoated tablets direct to the tablet coating drum.
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The Coperion K-Tron P-Series Pneumatic Receivers are ideal for applications with a higher degree of sanitary requirements such as vacuum conveying of difficult flowing powders and active pharmaceutical ingredients (API’s).