INSIGHTS ON SOLID DOSE MANUFACTURING
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Understanding Aseptic Powder Filling: Key Principles And Techniques
Pharmaceutical production of sterile powders presents unique hurdles. Explore the core principles and advanced techniques vital for aseptic filling, from containment to precise dosage control.
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Round Tablet Compression Tooling — To Key Or Not To Key The Punches
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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5 Advancements In Tablet Compression That Pharma Can't Ignore In 2026
New materials, smart automation, and in-press quality control are optimizing tablet compression. These five key innovations are driving efficiency and consistency in solid dose manufacturing today.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production8/15/2025
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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Segments: Next-Generation Tablet Press Technology10/7/2025
Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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From Concept To Market: Scaling And Manufacturing Semi-Solid Topical Drugs2/23/2026
Learn how formulation, processing, and scale‑up choices impact the stability, structure, and performance of semi‑solid topicals while ensuring consistent quality through development.
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Combining Patient Centricity And Commercial Viability In Pediatric Product Development8/15/2024
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
SOLID DOSE MANUFACTURING SOLUTIONS
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Master the art of tablet manufacturing with our comprehensive hands-on seminar, designed to equip you with in-depth knowledge and skills required for pharmaceutical and supplement manufacturing. This two and a half-day course covers essential topics such as tablet press setup, powder preparation, formulation, excipients, API, direct compression, wet granulation, dry granulation, tablet press operation, compaction, lubricants, and quality control.
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Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.
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Setting a New Benchmark for Ease of Operation
The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.
With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.
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Personal protection pharmaceutical isolators enables personal protection for operators when handling toxic substances.
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Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.