INSIGHTS ON SOLID DOSE MANUFACTURING
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Single-Use Containment And Oral Solid Dosage (OSD)
Flexible single-use containment systems achieve sub-microgram exposure levels while eliminating cleaning validation downtime for high-potency oral solid dose manufacturing.
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GLP-1 OSD Chemical Synthesis Workflow
Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.
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Exploring The Future Of Tablet Compression Across Emerging Industries
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Layer By Layer: 3D Screen Printing And The Future Of Drug Development
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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Reconstitutable Powder Filling System For Global MedTech Client9/3/2026
Custom automated powder dosing platforms streamline dual-powder aseptic device assembly, achieving high-speed precision and robust containment control
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Rational Design And Material-sparing Strategies For Enabled Intermediates And Drug Products9/9/2026
A material-sparing strategy integrating formulation mapping, lab-scale spray drying, and compact screening can accelerate risk identification and inform first-round tablet formulation decisions for poorly soluble APIs.
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Ask Us Anything: Jillian Sheeran On Emerging Reactor Technologies7/23/2026
Jillian Sheeran, Associate Director of Engineering at Snapdragon Chemistry, on how automation, feedback control, and machine learning are changing reactor design — with real-time monitoring that lets a process run continuously while the data comes to you.
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5 Hidden Risks In Early-Phase OSD Formulation Development8/31/2026
Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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Predicting Drug-Loading Limits In Tablet Formulations7/15/2026
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
SOLID DOSE MANUFACTURING SOLUTIONS
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AIM™ Pro Plus Control System Makes Tablet Production Easy
The Natoli AIM™ Pro Plus control system is a flexible software and hardware architecture that is standard on Natoli production tablet presses. This industry-leading package can be retrofitted to almost any production tablet press to increase production, improve tablet consistency, and provide an easier-to-manage production environment. -
Natoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.
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Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
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Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.
We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.
Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.
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Used ACG capsule filler, model AF TLab, speeds from 6000-25000 capsules/hour, 220 volt, CE design, batch# 2522/10/01, serial# 102, built 2020. includes ACG capsule polisher unit, model DP100, batch# DP62/30/21, serial# 2664, built 2020 and ACG empty capsule sorter, model ECS 100, batch# EC60/30/03, serial# 2098, built 2020.