INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Ensure operator safety and product purity with unidirectional airflow solutions. Explore how modular ISO 5 environments provide containment and cross-contamination control for critical processes.

  • Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

  • Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs.  Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.

  • Used Sejong rotary tablet press, model GRC-15C, 15 station, D tooled, 6 kn main compression, 2 kn pre compression, 25 mm max tablet diameter, 22 mm max depth of fill, with feed hoppers, rated up to 67500 tablets/hour, with integrated controls and touchscreen interface, serial# ST17866, built 2017.

  • Used 16 quart Patterson Kelly twin shell Blendmaster blender, 1 6 quart stainless steel shell, rated 200#/cu ft max material density, serial# C419381.