INSIGHTS ON SOLID DOSE MANUFACTURING
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GLP-1 OSD Chemical Synthesis Workflow
Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.
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Patient Adherence With A Novel Dosage Form
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Improving API Solubility Using Hot Melt Extrusion Formulation
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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Why Spray Drying Is Gaining Attention
Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.
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Cytiva's Aseptic Filling Workcell User Group1/9/2026
Discover how global collaboration among aseptic filling experts is driving innovation and improving operations.
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Contract Pharma 2026: Mikart On CDMO Collaboration4/30/2026
An overview of a milestone pharmaceutical outsourcing conference focused on CDMO collaboration, tech transfer, and oral solid and liquid dose manufacturing strategies.
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Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling7/15/2026
Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
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Compaction Simulation For Tablet Technology Transfer And Scale-Up7/15/2026
Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
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FastLok⢠Die Table Surface Overview10/8/2025
Learn about a toolless, removable surface that allows for rapid, on-turret plate replacement in minutes, not weeks, significantly improving operational efficiency.
SOLID DOSE MANUFACTURING SOLUTIONS
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Unused Stokes 560 tablet press tooling, tooling size: 3650 x 7850 inch Caplet, 44 Lower Punch/44 Upper Punch/44 Die, manufactured by Natoli.
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We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.
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Isolators with product protection as a housing for aseptic processes, e.g., filling, loading and unloading of freeze dryers.
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Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.
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Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.