INSIGHTS ON SOLID DOSE MANUFACTURING

• Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation

  Explore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.

• Predicting Drug-Loading Limits In Tablet Formulations

  Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

• Powder Rheology: Gateway For Tablet Sticking Insights

  Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.

• Optimising Solubility: Selecting The Right Technology For Early Drug Development

  Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.

• How To Address Your Solid Dosage Processing Needs

  10/27/2025

  Unlock the keys to consistent solid dosage products. Learn to align unique product needs with optimal processing requirements and equipment strategies. Gain a roadmap for improved quality and reproducibility.

• Exploring The Future Of Tablet Compression Across Emerging Industries

  11/18/2025

  Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.

• Lower Punch Tip Bending / Buckling

  11/11/2024

  When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

• Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling

  7/15/2026

  Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

• How To Avoid Sticking And Picking In The Tableting Industry

  9/23/2024

  Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.