INSIGHTS ON SOLID DOSE MANUFACTURING
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![Pharmaceutical technology-GettyImages-1137680279]( "Developing And Manufacturing Drugs With HPAPIs")
Developing And Manufacturing Drugs With HPAPIsLearn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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![3P innovation - achieving licensing]( "Achieving Licensing For A Healthcare Solution")
Achieving Licensing For A Healthcare SolutionFacing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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![GettyImages-488719432-bilayer-tablet-OSD-oral-solid]( "Customized Release Through Dispersed Dosage Formats")
Customized Release Through Dispersed Dosage FormatsTypically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
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![adare osd]( "Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing")
Combining Powdose® And Diffucaps® For Precise Solid Oral DosingCombining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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Layer By Layer: 3D Screen Printing And The Future Of Drug Development8/15/2025
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
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Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
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How To Address Your Solid Dosage Processing Needs10/27/2025
Unlock the keys to consistent solid dosage products. Learn to align unique product needs with optimal processing requirements and equipment strategies. Gain a roadmap for improved quality and reproducibility.
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Functional Release Multiparticulates Slam7/17/2024
Review Adare Pharma Solutions’ innovative technologies and learn how these capabilities can improve patient outcomes and improve manufacturing efficiency.
SOLID DOSE MANUFACTURING SOLUTIONS
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![3P - DPI filling]( "DPI Blister Filling Technology")
Explore scalable technology for forming, filling, and sealing blister strips, eliminating the need for costly redevelopment when moving from clinical to commercial production volumes.
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![Natoli - NCF 45]( "Automatic Pharmaceutical Capsule Filling System: NCF-45")
The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.
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![mdoel CF360EX]( "Used Vector Granulator: CF360E")
One (1) used Vectro granulator, mdoel CF360EX, stainless steel construction, 3-5 kg capacity, xp design with controls, 220 volt, serial# CF-110, new 1982.
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![Used Sejong 15 Station Phamaceutical Tablet Press]( "Used Sejong 15 Station Phamaceutical Tablet Press")
Used Sejong rotary tablet press, model GRC-15C, 15 station, D tooled, 6 kn main compression, 2 kn pre compression, 25 mm max tablet diameter, 22 mm max depth of fill, with feed hoppers, rated up to 67500 tablets/hour, with integrated controls and touchscreen interface, serial# ST17866, built 2017.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
