INSIGHTS ON SOLID DOSE MANUFACTURING
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Predicting Drug-Loading Limits In Tablet Formulations
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
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Developing And Manufacturing Minitablets To Extend Drug Lifecycle
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
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How To Avoid Sticking And Picking In The Tableting Industry
Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.
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Advancing High Potency Manufacturing
Advance potent drug manufacturing through tighter containment, thoughtful process engineering, and closed handling that protects workers while improving efficiency and scale.
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Patient Adherence With A Novel Dosage Form11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies7/15/2026
In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery1/27/2025
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets1/27/2025
Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.
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Engineering Challenges Of Designing Pharmaceutical Isolators3/27/2025
Designing pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
SOLID DOSE MANUFACTURING SOLUTIONS
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The patented DCS® pharmaceutical Drum Containment System is a stainless steel cylindrical glove box with a glass cover and two glove ports. Highly economical in comparison with conventional isolation systems, DCS® ensures precise, contamination free emptying of drums providing high containment (< 1 µg/m3).
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Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.
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ROSS Ribbon Blenders efficiently mix powders, granules, and bulk solids across industries, offering customizable lab-to-production models for various bulk densities, including heavy-duty and sanitary applications.
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Dec provide custom designed isolators for dispensing and/or sampling from various containers such as bags and drums into intermediate packaging or for direct charging into process equipment. These systems offer high containment and a controlled environment offering fast cleaning and drying features allowing for swift product changes.
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Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.