INSIGHTS ON SOLID DOSE MANUFACTURING

• Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months

  A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.

• Enabling Complex Phase IIa Dosing Through Flexible Clinical Packaging Design

  Discover how flexible, patient‑centric clinical packaging supports complex Phase IIa dosing while protecting timelines, ensuring compliance, and avoiding costly primary packaging changes.

• Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing

  Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.

• Solubility Enhancement Via Amorphous Solid Dispersions

  Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.

• Benefits Of Single-Use Isolators For Cytotoxic Payload Handling

  6/15/2026

  Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.

• Minitablets: Enhancing Safety And Palatability For Pediatric Medicines

  1/15/2026

  Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.

• Achieving Manufacturing Efficiency In OSD Manufacturing

  10/16/2024

  Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.

• Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability

  7/15/2026

  Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.

• Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies

  7/15/2026

  In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.