INSIGHTS ON SOLID DOSE MANUFACTURING
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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Die Bore Cracking: How To Achieve Reliable Tablet Production
Die bore cracking is a significant issue in tablet manufacturing, affecting the quality of the tablets and potentially damaging the tablet press. Explore how to analyze for and prevent this damage.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Smart Softgels: Driving Innovation In Pharma
Learn about how softgels are poised to facilitate innovation in the pharmaceutical industry as well as ongoing advancements in optimizing drug bioavailability through nano formulations.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying7/16/2024
Although well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production8/15/2025
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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Developing And Manufacturing Drugs With HPAPIs1/27/2025
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets1/27/2025
Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.
SOLID DOSE MANUFACTURING SOLUTIONS
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Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
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Used Kilian rotary tablet press, model T100, 16 station, B/D IPT turret, with (8) B tooled, 16 mm diameter, 16 mm depth of fill and (8) D tooled, 25 mm diameter, 16 mm depth of fill stations in single turret, with additional 9 station IPT B toolded turrent, 42 Kn pre-compression, 65 Kn main compression, keyed upper punch guides, singled sided with force feeder, commission# 706849, built 2002.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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PTS Powder Transfer System® challenges convention by using both vacuum and pressure to move powders as if they were liquids. This eliminates the need for gravity charging and therefore making multi floor processes a requirement of the past.
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Used Glatt GPCG2 LabSystem Fluid Bed Dryer, 200-460V, 50/60Hz, 3 PH, serial# 79589, built 2013.