INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.

  • The mixer is loaded with the individual raw materials exactly according to the formulation. The combination of Dosicon®  weighing equipment with suction conveying units fulfils this task. Fundamental advanrages of JetSolutions automatic multi-component dosing are high dosing accuracy (for quantities ranging from a few hundred grams to several hundred kilos), the prevention of cross-contamination risks, and freedom from dust.

  • Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.

    Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.

  • Explore a mid-sized tablet press designed with optional features including force monitoring, a power rotary forced feeder, a tablet reject chute, and a hopper vibration unit.

  • Active pharmaceutical ingredient (API) manufacturing requires powder handling in a GMP and contained manner. Similar to chemical manufacturing, operations like charging powders into a chemical reactor, emptying a centrifuge or charging and discharging a dryer are standard processes.