INSIGHTS ON SOLID DOSE MANUFACTURING

• The Keys To Superior Containment In Compounding Applications

  This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process. 

• Managing Risks With Potent Pharmaceutical Products

  Managing the risks associated with potent compounds requires a knowledgeable team as well as the design and implementation of an effective safety program.

• Selecting The Best Pharmaceutical Mixing Equipment For Your Operations

  Finding the right mixing equipment isn’t as simple as selecting an item from a menu. This article is a guide to considerations when choosing pharmaceutical mixing equipment and vendors for a facility.

• Considerations When Cleaning Your Tablet Presses & Tablet Tooling

  Implementing a cleaning procedure is essential to maintaining your tablet tooling and presses. Dirty tools cause tableting and product quality-related problems, such as sticking & picking. Keeping tools clean also decreases premature tool, turret and cam wear, and reduces the risk of product cross-contamination. While most cleaning methods can achieve similar results, utilizing an automated cleaning system, such as an ultrasonic wash with rinse and dryer, can ensure tooling is properly cleaned and dried consistently with limited handling and potential for damage. A warm air-drying process is ideal for preventing moisture and corrosion by pushing warm air through areas, such as key slots, punch cups, and die bores, that may not be dried properly with a traditional towel or cloth.

• Overcoming Encapsulation Issues Caused By Sticky Formulations

  This guide provides a best-practices approach to troubleshooting capsule-filling problems when handling a sticky product formulation.

• A Proven, Cost-Effective, Single-Use Powder Transfer Solution

  Powder-handling processes haven’t kept pace with advances in single-use transfer technologies. This application note posits a better way to bring powders to the hydration process for upstream manufacturing.

• Using Positive Controls In Container Closure Integrity Studies

  This webinar describes the use of positive controls as an important element of CCI studies designed to validate packaging components for CCI or to qualify processes for producing good CCI.

• Choose The Right Inline High-Shear Mixer For Your Process

  This white paper presents some ideas for selecting the right inline high shear mixer for your process based on a company’s collective experience as a mixing equipment provider to process industries.

• Pfizer Installs Feeding Systems For Continuous Manufacturing Operations

  Compact arrangement of pharmaceutical feeders supplied by Coperion K-Tron accurately deliver ingredients into the continuous mixing process, guaranteeing consistent and high quality end products.