INSIGHTS ON SOLID DOSE MANUFACTURING
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GLP-1 OSD Chemical Synthesis Workflow
Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.
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Predicting Drug-Loading Limits In Tablet Formulations
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
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Overload Setting – Tricks And Techniques
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
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Future-Proofing Aseptic Manufacturing3/27/2025
Investing in adaptable aseptic manufacturing pays off. Find out how flexible systems, despite higher initial costs, handle complex drugs and changing volumes to boost productivity and quality.
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Navigating High-Potency OSD Manufacturing4/13/2026
Learn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.
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Lipid Formulation Development: Why Softgels Are The Technology Of Choice8/31/2026
Low bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
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An Alternative Method Of Drug-Excipient Characterization12/30/2024
Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
SOLID DOSE MANUFACTURING SOLUTIONS
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The pneumatic POSITIVE pressure conveying (or PRESSURE conveying) is dedicated to the transfer of larger quantities of powder or granulates under following conditions:
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Used Manesty Unipress rotary table press, 34 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 11 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, with control cabinet, up to 247,200 tablets/hour, serial# 15458 84.
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Natoli Engineering’s NP-P20A single-station hydraulic tablet press is a favorite for the production of injectable micropellets and for marginal formulations requiring deep-fill. The NP-P20A meets the FDA’s requirements for batch reporting and secure data management under CFR 21 Part 11 compliance.
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Open RABS as a housing for aseptic processes, e.g., filling, loading, and unloading of freeze dryers. Product protection is achieved by a barrier (oRABS housing with gloves) between the operator and the product.
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Inno4Life, part of the Dec Group, has in-depth knowledge and containment equipment solutions for the aseptic/sterile Fill-Finish pharmaceutical industry. In line with ISO 14644, including monitoring of viable and non-viable monitoring to comply with the most recent revisions of the ISPE containment specifications cGMP and GAMP5 guidelines.