INSIGHTS ON SOLID DOSE MANUFACTURING

  • Blister Solutions

    With over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.

  • An Alternative Method Of Drug-Excipient Characterization

    Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.

  • Achieving Licensing For A Healthcare Solution

    Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.

  • Powder Rheology: Gateway For Tablet Sticking Insights

    Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.

SOLID DOSE MANUFACTURING SOLUTIONS

  • Used Vector Freund roller compactor system, model TFC-LABO, stainless steel construction, approximately 50 mm roll diameter x 24 mm roll face width rolls, vertical compression screw with motor, with motor controllers for rolls and feed screw, rated 5 g-1 kg/hour production speed, with Vector oscillating granulator, serial# RC-266 46483, built 2008.

  • Used GEA Mobile Minor Spray Dryer, Model MM-PSR, stainless steel construction, 0.8 meter diameter chamber, GEA Niro nozzle atomixer, cone bottom, with top expansion chamber, with inlet HEPA filter housing, cyclone fines collector, discharge filter housing, and .95 kw blower, control panel with Allen Bradley Panelview1500 HMI, project# 1093-2412, built 2017.

  • Used ThermoScientific Haake Pelletizing line, with model Phama 11 HME twin screw extruder, item# 553-0020, co-rotating screws, 40:1 l/d, 1000 rpm screw speed, 1.5 kw motor drive, with feeder, and operator HMI touchscreen. ThermoScientific Ph11 Conveyor, item# 553-0600, serial# 1-21004125001. ThermoScientific pelletizer, 6 blade rotor with pull roll, 230 volt, CE design, extruder machine# KU18-000011, serial# 1-1800319001, built 2019.

  • Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.

    We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).

    Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.

  • The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.