INSIGHTS ON SOLID DOSE MANUFACTURING
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Bridging The Gap Between Product Readiness And Equipment Availability
Discover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
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Layer By Layer: 3D Screen Printing And The Future Of Drug Development
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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Customized Release Through Dispersed Dosage Formats
Typically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
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Future Of Pharma Packaging: Trends, Tech, And Patient Solutions9/25/2025
Explore how traditional and innovative pharmaceutical packaging formats improve patient adherence, support emerging therapies, and shape the future of drug delivery and treatment outcomes.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production8/15/2025
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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Overload Setting – Tricks And Techniques9/23/2024
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
SOLID DOSE MANUFACTURING SOLUTIONS
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Explore aseptic filling line solutions that offer an easy-to-operate system designed to enhance production efficiency and reduce changeover time.
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Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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Ropack Pharma Solution’s ample, nimble capacity and validated processes bring quality and reliability to encapsulation.
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Understanding the fine details of powder properties is crucial in the pharmaceutical industry, where the behavior of particulate matter can affect manufacturability and the efficacy of the final product.
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The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.