INSIGHTS ON SOLID DOSE MANUFACTURING
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Patient Adherence with A Novel Dosage Form
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Achieving Manufacturing Efficiency In OSD Manufacturing
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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Understanding Aseptic Powder Filling: Key Principles And Techniques
Pharmaceutical production of sterile powders presents unique hurdles. Explore the core principles and advanced techniques vital for aseptic filling, from containment to precise dosage control.
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Achieving Licensing For A Healthcare Solution
Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions8/11/2025
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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FastLok⢠Die Table Surface Overview10/8/2025
Learn about a toolless, removable surface that allows for rapid, on-turret plate replacement in minutes, not weeks, significantly improving operational efficiency.
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Innovative ASD Technology Improves Abandoned Cancer Medication3/1/2024
Review this case to learn how one solid dispersion technology lowered patients' pill burdens and demonstrated an improved therapeutic response for Galeterone.
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Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?7/30/2024
What is head pressure in your hopper and how does it relate to tablet press performance?
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The Critical Role Of Weight Uniformity In Tablet Manufacturing7/11/2024
For tablet manufacturers, tablet weight uniformity plays an essential role in ensuring pharmaceutical products deliver accurate amounts of key ingredients in a formulation.
SOLID DOSE MANUFACTURING SOLUTIONS
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Bausch + Strobel SP-100 Powder filling Machine with control cabinet, stainless steel construction, with filler funnels and auger, serial# 51181, built 1998.
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Combination Powder and Fume Hood with HEPA filtration and house exhaust connection designed to process liquid and powder substances. Fume Hood designed to house stir plate and analytical balance. It features cup sink; air, water, and gas fittings; and alarm for monitoring and maintaining recommended face velocity of 75 LFPM. Fume and Powder Hoods separated by sliding door to eliminate cross-contamination during processing. Powder Hood uses front airfoils and rear plenums to maintain laminar airflow across the work surface, which is vented through a HEPA filtration system to house exhaust.
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Over many years, Dec has acquired recognized expertise in designing and supplying an extensive range of isolators enclosing a mill or a MC DecJet® spiral jet mill for either individual or combined operation.
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The pharmaceutical industry has steadily moved to increased production and handling of sterile highly potent active ingredients (HPAPIs). Dec’s containment technologies comply with pharmaceutical quality manufacturing standards and are available for aseptic operations.