INSIGHTS ON SOLID DOSE MANUFACTURING
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![Natoli - EZ Level]( "Maximize Uptime And Yield With This Feeder Base Leveling System")
Maximize Uptime And Yield With This Feeder Base Leveling SystemLearn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
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![GettyImages-1002000796-lab-research-scientist-development]( "Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives")
Closing The Duration Gap In FDA-Approved Long-Acting ContraceptivesA gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.
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![Bridging The Gap Between Product Readiness And Equipment Availability]( "Bridging The Gap Between Product Readiness And Equipment Availability")
Bridging The Gap Between Product Readiness And Equipment AvailabilityDiscover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
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![cdmo-solid-dose-GettyImages-1432665138]( "Safely Scaling High Potency API Manufacturing")
Safely Scaling High Potency API ManufacturingScaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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Exploring The Future Of Tablet Compression Across Emerging Industries11/18/2025
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Automated Precision Powder Filling For Annex 11/21/2026
Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.
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Rheological Properties Of Pharmaceutical Excipients: Lactose Monohydrate And Carboxymethyl Cellulose12/30/2024
Explore lactose monohydrate and CMC rheology, highlighting their flow, cohesion, and compressibility properties to optimize pharmaceutical formulations under varying stress and temperature conditions.
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Solvent-Free, Fusion-Based Amorphic Dispersion Process7/11/2024
Discover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Getty Images-823447656-vector-viral-lab-AAV-cell-development]( "Global Experts In Nanotechnology And Drug Particle Engineering")
Discover the nanoparticle engineering, formulation and GMP manufacturing services that can drive forward your market success and unlock the power of “small."
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![Dec 1]( "Loading And Charging Of Drums For High Potent API's: IsoTube")
Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs. Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.
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![Natoli EZ Level bucket img]( "EZ Level Feeder Table Leveling System")
Stop wasting time on frustrating, trial-and-error methods to level your tablet press feeder platform. "Close enough" isn't good enough—especially when it leads to excess formulation loss or costly equipment damage. With the Natoli EZ Level™ Feeder Base Leveling System, you can achieve fast, accurate, and repeatable results—every time.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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![Big Bag Pharma]( "Big Bag Pharmaceutical Filling System For Drums, Boxes, Flexible IBC's")
If you handle multiple packaging, Dec can help in providing one single multi-packaging filling station handling FIBCs, drums, cardboard boxes etc.).
