INSIGHTS ON SOLID DOSE MANUFACTURING
-
Building Oral Dosage Forms for Speed Today And Success Tomorrow
Move toward the clinic with confidence using integrated development strategies that support smarter decisions and more efficient product development.
-
Why Spray Drying Is Gaining Attention
Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.
-
Solubility Enhancement Via Amorphous Solid Dispersions
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
-
How To Handle Intrinsic Product Powder Particles
Powder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
-
Predicting Drug-Loading Limits In Tablet Formulations7/15/2026
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
-
A Simple And Powerful Solution For Accelerating Dissolution5/5/2026
Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.
-
Direct API Capsule Filling: A Faster Path To Market9/16/2026
Direct API capsule filling eliminates complex formulation steps, leveraging volumetric drum dosing and 100% net weight verification to accelerate drug development timeline efficiency.
-
Tablet And Capsule Inspection: Detecting Defects Before They Ship8/3/2026
Inline X-ray inspection identifies density variations and foreign contaminants in solid dose products to prevent costly recalls and ensure strict quality compliance.
-
From Disruption To Reinvention: The Story Of API-In-Capsule Technology And Its Future8/19/2025
Discover how advanced API-in-capsule technology addresses previous limitations, providing a flexible and efficient path for drug candidates from development to clinical trials.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Used Korsch rotary tablet press, model PH250/25, 25 station, 20 Kn pre compression, 80 Kn main compression, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder, rated up to 180000 tablets/hour, serial# 1.0031.94, built 1994.
-
Solid form screening optimizes drug properties by evaluating polymorphs, salts, and cocrystals to improve solubility, stability, and manufacturability using advanced analytics.
-
Inno4Life, part of the Dec Group, has in-depth knowledge and containment equipment solutions for the aseptic/sterile Fill-Finish pharmaceutical industry. In line with ISO 14644, including monitoring of viable and non-viable monitoring to comply with the most recent revisions of the ISPE containment specifications cGMP and GAMP5 guidelines.
-
Used MG2 Planeta 100 continuous motion capsule filler with touch screen HMI, vacuum system, serial# 4661, built 2010.
-
Used O'Hara LabCoat bench-top coating pan, model LABCOAT BT, stainless steel product contact surfaces, with 8.5" perforated pan with plenum, spray guns with Watson Marlow peristaltic pump system, on board air handling system, electrically heated, Siemens controls, 220 volt, 1 phase, 60 hertz, serial# 414, built 2015.