INSIGHTS ON SOLID DOSE MANUFACTURING

• Lower Punch Tip Bending / Buckling

  When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

• Predicting Drug-Loading Limits In Tablet Formulations

  Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

• Beyond Development: Using Continuous Manufacturing To Accelerate OSD Commercialization

  Hear firsthand insights from Douglas B. Hausner, Ph.D., Senior Manager of Continuous Manufacturing, on the company’s first OSD product submission enabled by continuous manufacturing and Real-Time Release Testing.

• Why Spray Drying Is Gaining Attention

  Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.

• Exploring The Future Of Tablet Compression Across Emerging Industries

  11/18/2025

  Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.

• How To Achieve Late-Phase Success In Complex OSD Development

  8/31/2026

  Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.

• Ask Us Anything: Jillian Sheeran On Emerging Reactor Technologies

  7/23/2026

  Jillian Sheeran, Associate Director of Engineering at Snapdragon Chemistry, on how automation, feedback control, and machine learning are changing reactor design — with real-time monitoring that lets a process run continuously while the data comes to you.

• Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery

  1/27/2025

  Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.

• Powder Rheology: Gateway For Tablet Sticking Insights

  10/7/2025

  Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.