INSIGHTS ON SOLID DOSE MANUFACTURING
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Nanoparticle Engineering Addresses The Challenge Of Poor Aqueous Solubility
As pharma companies aim to overcome development obstacles, it is important to incorporate GMP expertise alongside novel technologies that can enhance the properties of APIs and dosage forms.
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Key To Formulation Development Is In The Details
Find out how to face the challenges in tablet manufacturing environments through supportive vendor partnerships.
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Tablet Compression Tooling: Land Or No Land?
Explore why tablet land, the horizontal surface perpendicular to the tablet's periphery, should be designed using a holistic approach.
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Impact Of Water Activity On The Potency, Purity And Bioavailability Of Oral Solid Dosage Products
Explore laser-based headspace analysis, the impact of USP<922> Water Activity on primary packing selection, and the impact of water activity on the potency, purity, and bioavailability of OSD products.
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Tablet Characterization With Regulatory Compliance Method USP<1062>9/26/2022
This video explores different punch cup configuration, the comparison compression and granulation techniques, and how it impacts USP<1062> profiles.
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A Micronization Method Enabling The Formulation Of Biopharmaceuticals6/29/2023
Micronization is key for increasing the loading efficiency and lowering the burst of microspheres. Applying lyophilization-based micronization methodology at a small scale helps to support challenging formulation development projects.
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Validated HPLC-UV Method For Quantification Of Paxalisib1/18/2023
Examine research into the development and validation of an HPLC method for the quantitation of paxalisib in mouse plasma and its potential use for routine therapeutic drug monitoring.
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KinetiSol™ Technology3/6/2024
For poorly soluble drugs, overcoming absorption hurdles can hinder development. KinetiSol™ Technology empowers researchers to overcome solubility limitations and accelerate drug development.
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Precision Powder-In-Capsule Micro-Dosing Accelerates Drug Development6/1/2022
Precision powder microdosing makes it possible to quickly get formulations to the clinic, saving time, money, and use of limited APIs.
SOLID DOSE MANUFACTURING SOLUTIONS
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In pharmaceutical manufacturing containment performance is critical to minimize operator exposure and process cross contamination.
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Used MG2 continuous motion capsule filler, model Planeta100, nominally rated up to 100,000 capsules/hour, currently set up for microdose capsules, multinet weight control unit less scale system, 460 volt, serial# 4697, built 2014.
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We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.
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Coperion K-Tron’s family of twin and single screw microfeeders has been specially designed to provide maximum accuracy at minimal feed rates, which makes these feeders ideal for use in the chemical and pharmaceutical processing industries. Unique design features ensure that high value ingredients are fed accurately at rates as low as 32 g/h with minimal residual material left in the feeder. The modular design means more flexibility for the process and easy access to all parts for cleaning and maintenance. The 12 mm and 16 mm twin and single screw feeding modules are completely interchangeable and can feed a wide range of free-flowing to difficult powders.
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The Coperion K-Tron Microfeeder for low rate powder feeding includes design options for handling toxic powders as well as difficult flowing materials.