INSIGHTS ON SOLID DOSE MANUFACTURING
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Advances In Oral GLP-1 Analogs For Obesity
Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.
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A Technology Driven CDMO & Trusted Manufacturing Partner
Whether it's through extended release formulations or titratable dosage forms, we are dedicated to addressing the specific needs of different patient populations, including pediatrics and geriatrics.
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Softgel Formulation: Addressing Stability, Shelf-Life, And Bioavailability
A CDMO that has expertise and resources in softgel formulation can help companies address stability issues, improve drug bioavailability, or ensure compliance with regulations.
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Automated Precision Powder Filling For Annex 1
Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.
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Pharmaceutical X-Ray Counts Capsules And Pills8/15/2025
See how advanced x-ray inspection technology verifies correct pill count, identifies broken capsules, and detects foreign contaminants in pharmaceutical sachet packets.
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Understanding Aseptic Powder Filling: Key Principles And Techniques3/27/2025
Pharmaceutical production of sterile powders presents unique hurdles. Explore the core principles and advanced techniques vital for aseptic filling, from containment to precise dosage control.
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Innovations, Solutions, And USP <1062> With Scale Up11/4/2025
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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Overload Setting – Tricks And Techniques9/23/2024
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing6/30/2025
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
SOLID DOSE MANUFACTURING SOLUTIONS
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Each service visit will include the following:
- Preventative Maintenance
- Equipment inspection (paddle feeder, tachometer, cams, compression rollers, etc.)
- Turret inspection
- Additional Operator and Technician Training
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Used Sejong rotary tablet press, model GRC-15C, 15 station, D tooled, 6 kn main compression, 2 kn pre compression, 25 mm max tablet diameter, 22 mm max depth of fill, with feed hoppers, rated up to 67500 tablets/hour, with integrated controls and touchscreen interface, serial# ST17866, built 2017.
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This micro auger filling system is designed for the precision filling of injection devices, vials, cartridges, syringes, inhalers, and sachets, with dosing capabilities from 10mg to 20g.
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Used Manesty Unipress rotary table press, model MFG 765, 27 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, with control cabinet, up to 196,200 tablets/hour, serial# 15578 85.