INSIGHTS ON SOLID DOSE MANUFACTURING
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![cdmo-solid-dose-GettyImages-1432665138]( "Safely Scaling High Potency API Manufacturing")
Safely Scaling High Potency API ManufacturingScaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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![Bridging The Gap Between Product Readiness And Equipment Availability]( "Bridging The Gap Between Product Readiness And Equipment Availability")
Bridging The Gap Between Product Readiness And Equipment AvailabilityDiscover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
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![GettyImages-1499814881-pills-production-line]( "Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months")
Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 MonthsA development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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![Tablet Dissolving GettyImages-851893518]( "Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates")
Orally-Disintegrating Dosage Forms With Taste Masked MultiparticulatesLearn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
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Solvent-Free, Fusion-Based Amorphic Dispersion Process7/11/2024
Discover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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How To Avoid Sticking And Picking In The Tableting Industry9/23/2024
Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.
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How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions8/11/2025
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges2/3/2025
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Maximize Uptime And Yield With This Feeder Base Leveling System10/8/2025
Learn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
SOLID DOSE MANUFACTURING SOLUTIONS
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![GettyImages-163720603 tablet press, OSD]( "From Formulation To Global Supply: Mastering Oral Solid Development")
A global, integrated approach to oral solid dosage development combines formulation science, advanced delivery, and scalable manufacturing to support efficient clinical progress and reliable supply.
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![iStock-1191001266-tablet-pill]( "Oral Solid Dose Formulation Troubleshooting Support Services")
Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.
We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).
Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.
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![flexiblecontainmentisolators]( "Flexible Containment Isolators")
Flexible Containment Isolators provide containment standards better than can be achieved with Downflow Booth technology, and often compare favorably with a Rigid Isolator system.
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![Tablet Press NP255]( "Pharmaceutical Rotary Tablet Press: NP-255")
Setting a New Benchmark for Ease of Operation
The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.
With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.
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![K-Tron Powder Delumper Hopper]( "Used K-Tron Powder Delumper Hopper")
Used K-Tron powder delumper hopper, stainless steel construction, with .5 hp, 230/460 volt motor drive with VFD controllers.
