INSIGHTS ON SOLID DOSE MANUFACTURING
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Technologies And Patient-Centric Solutions
Our innovative technology platforms, including Taste Masked Microcaps® and Optimµm®, address issues like taste masking, swallowability, and controlled release to improve patients' quality of life.
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How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
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Innovations, Solutions, And USP <1062> With Scale Up11/4/2025
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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Smart Softgels: Driving Innovation In Pharma7/29/2024
Learn about how softgels are poised to facilitate innovation in the pharmaceutical industry as well as ongoing advancements in optimizing drug bioavailability through nano formulations.
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Contract Pharma 2026: Mikart On CDMO Collaboration4/30/2026
An overview of a milestone pharmaceutical outsourcing conference focused on CDMO collaboration, tech transfer, and oral solid and liquid dose manufacturing strategies.
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Spray Dry Biologics For Oral Dosage Forms5/15/2026
Spray drying enables stable oral delivery of biologics by creating protective dry powders, improving bioavailability, stability, and targeted release compared with traditional formulation methods.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
SOLID DOSE MANUFACTURING SOLUTIONS
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Used Sensum tablet inspection machine, model SPINE, designed for inspection of complete surface of tablets, including engraving, speeds up to 360,000 tablets/hour for round and oblong plain tablets, 240,000/hour for engraved round tablets, 300,000 tablets/hour for oblong engraved tablets, with stainless steel product hopper and integrated operator HMI, 230 volt, 60 hertz, CE design, serial# 073, built 2017.
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Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs. Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.
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Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
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Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.
We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.
Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.
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Master the art of tablet manufacturing with our comprehensive hands-on seminar, designed to equip you with in-depth knowledge and skills required for pharmaceutical and supplement manufacturing. This two and a half-day course covers essential topics such as tablet press setup, powder preparation, formulation, excipients, API, direct compression, wet granulation, dry granulation, tablet press operation, compaction, lubricants, and quality control.