Solid Dose Manufacturing

INSIGHTS ON SOLID DOSE MANUFACTURING

Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications
More than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
Compaction Simulation For Tablet Technology Transfer And Scale-Up
Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
GLP-1 Oral Solid Dosage Workflow - Spray Drying And Tableting
Optimize containment in oral GLP-1 solid dose manufacturing. Learn how closed single-use containment and flexible isolators secure blending, spray drying, and tableting workflows.

Patient Adherence With A Novel Dosage Form
11/13/2025

A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
Liquid Suspension Trends In The CDMO Space
1/15/2026

Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
Optimising Solubility: Selecting The Right Technology For Early Drug Development
5/6/2026

Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.
How To Achieve Late-Phase Success In Complex OSD Development
8/31/2026

Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
Future-Proofing Aseptic Manufacturing
3/27/2025

Investing in adaptable aseptic manufacturing pays off. Find out how flexible systems, despite higher initial costs, handle complex drugs and changing volumes to boost productivity and quality.

Capsule Filling And Weighing

Scalable capsule filling systems streamline product development from lab testing to production. See how interchangeable dosing modules handle precise combinations of powders, liquids, and more.
Drug Product Manufacturing

GMP drug product manufacturing supports solid dose and sterile parenteral development with formulation expertise, isolator fill‑finish, DEA‑licensed work, packaging, labeling, and supply‑chain services.
Nutritional Tablet Manufacturing Equipment

Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.
Negative, Total Exhaust Containment Isolator

Secure your laboratory environment when handling infectious materials. High-containment systems provide leak-tight protection for BSL 2+ through 4 applications, ensuring operator safety.
Pharmacon™ Downflow Booth Generation 3

Esco Pharma's Downflow Booth Generation 3 (DFBG3) is a new generation of Esco powder containment booth which provides simplicity with assured quality.