INSIGHTS ON SOLID DOSE MANUFACTURING

• Ask Us Anything: Hannah McLachlan on Crystallization In Peptide Development

  Hannah McLachlan, Project Scientist IV at Cambrex Edinburgh, on what crystallization screening delivers for peptide therapeutics — more stable material, higher purity, and a molecule clients can store without specialist infrastructure.

• Maximum Protection With Superior Quality

  See how this automated capsule filling technology integrates high-containment isolators and 100% inline checkweighing to ensure precise dosing, operator safety, and continuous quality control

• Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation

  Explore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.

• Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications

  More than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.

• Rheological Properties Of Pharmaceutical Excipients: Lactose Monohydrate And Carboxymethyl Cellulose

  12/30/2024

  Explore lactose monohydrate and CMC rheology, highlighting their flow, cohesion, and compressibility properties to optimize pharmaceutical formulations under varying stress and temperature conditions.

• Decontamination Of Aseptic Pharmaceutical Isolators Using Vaporized And Aerosolized Hydrogen Peroxide

  8/26/2026

  Aerosolized hydrogen peroxide decontamination cuts isolator cycle times from 70 to 15 minutes while drastically reducing biocide and overall energy usage.

• Small-Scale Automatic Micro-Dosing Of Powders Into Blisters

  9/2/2026

  Optimize inline X-ray fill weight verification with precise blister calibration, automated HMI calibration file creation, and 2D code tracking.

• Innovations, Solutions, And USP <1062> With Scale Up

  11/4/2025

  Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.

• Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up

  9/9/2026

  SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.