INSIGHTS ON SOLID DOSE MANUFACTURING

• From Disruption To Reinvention: The Story Of API-In-Capsule Technology And Its Future

  Discover how advanced API-in-capsule technology addresses previous limitations, providing a flexible and efficient path for drug candidates from development to clinical trials.

• Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling

  Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

• Benefits Of Isolator Technology In Fill-Finish

  Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.

• A Brief History Of Aseptic Processing

  From Bunsen burners to advanced isolators, aseptic processing has evolved significantly. Delve into the evolution of this crucial manufacturing method, from its early sterilization techniques to today's highly controlled and regulated environments.

• Global Regulatory Harmonization: Comparisons In Aseptic Barrier Systems

  4/20/2026

  Compare global aseptic standards from the FDA, EMA, PIC/S, and WHO. Gain insights into how advanced barrier systems harmonize international requirements to ensure sterile product integrity and safety.

• Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets

  1/27/2025

  Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.

• Predicting Softgel Stability And Shelf Life Using Accelerated Modeling

  7/15/2026

  Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

• Reducing Uncertainty In Early Oral Drug Development

  8/31/2026

  Five recurring decision points in early oral solid dose development carry outsized downstream consequences. AI/ML-driven predictive modeling is reframing how teams manage those decisions under API and timeline constraints.

• Advances In Oral GLP-1 Analogs For Obesity

  9/12/2024

  Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.