INSIGHTS ON SOLID DOSE MANUFACTURING
-
![3P Innovation - isolator]( "Engineering Challenges Of Designing Pharmaceutical Isolators")
Engineering Challenges Of Designing Pharmaceutical IsolatorsDesigning pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
-
![GettyImages-1097562996-pill-tablet-capsule-OSD-oral-solid]( "Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation")
Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling FormulationExplore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.
-
![GettyImages-1938554519-lab-computer-research-discovery]( "The Future Of Sustainable Amorphous Dispersion Development")
The Future Of Sustainable Amorphous Dispersion DevelopmentSustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
-
![GettyImages-2270210340-lipid-nanoparticle-delivery-system]( "Lipid Formulation Development: Why Softgels Are The Technology Of Choice")
Lipid Formulation Development: Why Softgels Are The Technology Of ChoiceLow bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
-
Why Spray Drying Is Gaining Attention7/20/2026
Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.
-
Achieving Licensing For A Healthcare Solution6/16/2025
Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
-
How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions8/11/2025
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
-
Liquid Suspension Trends In The CDMO Space1/15/2026
Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
-
Lower Punch Tip Bending / Buckling11/11/2024
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
SOLID DOSE MANUFACTURING SOLUTIONS
-
![Medicine-pills-tablets-GettyImages-545993684]( "USP<1062> Tablet Compression Characterization")
Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
-
![Filling of Powders into Drums and Bag]( "Filling Of Powders Into Drums And Bags")
Dec excels in providing comprehensive technical solutions for packing powders into bags and drums from process equipment discharge such as a dryer or a mixer, milling and dispensing to the final packing of the product.
-
![Tablet Capsule Manufacturing Process-GettyImages-1669462992]( "Capsule Filling And Weighing")
Scalable capsule filling systems streamline product development from lab testing to production. See how interchangeable dosing modules handle precise combinations of powders, liquids, and more.
-
Dec’s Big Bag filling stations offer a variety of packaging concepts. These range from simple inflatable gaskets to liner systems which, if necessary, can be integrated into a glove box. The filling systems are of a modular design depending on the process and containment requirements.
-
![GENiSYS C rendering]( "Biosimilar Development Aseptic Filling Equipment")
With many of the blockbuster biologic drugs of the ’90s are coming off of patent, companies are racing to provide a clinically similar alternative to these pioneering products. Like any biologic drug, they require care and attentiveness throughout the manufacturing process. Therefore, it is necessary to maintain aseptic conditions throughout the production process of these drug products.
