INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-488719432-bilayer-tablet-OSD-oral-solid]( "Customized Release Through Dispersed Dosage Formats")
Customized Release Through Dispersed Dosage FormatsTypically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
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![3P Innovation - isolator]( "Engineering Challenges Of Designing Pharmaceutical Isolators")
Engineering Challenges Of Designing Pharmaceutical IsolatorsDesigning pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
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![Dalton photo 1]( "Automated Precision Powder Filling For Annex 1")
Automated Precision Powder Filling For Annex 1Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.
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![GettyImages-1208573753-scientist-fizz-solubility-lab-glass]( "Improving API Solubility Using Hot Melt Extrusion Formulation")
Improving API Solubility Using Hot Melt Extrusion FormulationSolubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production8/15/2025
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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5 Advancements In Tablet Compression That Pharma Can't Ignore In 202611/4/2025
New materials, smart automation, and in-press quality control are optimizing tablet compression. These five key innovations are driving efficiency and consistency in solid dose manufacturing today.
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Low-Bioburden Powders For Terminal Sterilisation2/24/2026
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
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Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives7/17/2024
A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Used Korsch XL 400 2-Layer Tablet Press]( "Used Korsch XL 400 2-Layer Tablet Press, 35/29 Station")
Used Korsch XL 400 2-Layer rotary tablet press. 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.
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![ConveyingOfGranules.jpg]( "Conveying Of Granules, Flakes And Large Sized Particles: Transbatch")
The patented Transbatch system relies on modern technology to safely convey and dose granules and other solids under critical installation conditions in terms of both transfer length and height.
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![Flexible containment]( "Pharmaceutical Flexible Containment Systems: Isolators, Enclosures, Glove Bags")
Dec has designed a wide range of versatile and low cost flexible containment solutions such as disposable glove bags, complete flexible enclosures and semi-rigid isolators suitable for many operations whether it be formulation plants including dispensing and granulation or around tablet pressing machines for both R&D and production facilities.
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![Medicine-pills-tablets-GettyImages-545993684]( "USP<1062> Tablet Compression Characterization")
Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
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![Nutritional Tablet Manufacturing Equipment]( "Nutritional Tablet Manufacturing Equipment")
Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.
