INSIGHTS ON SOLID DOSE MANUFACTURING

• Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric Oncology

  When an oral liquid formulation of crizotinib failed pediatric trials due to intolerable taste and irritation, a multiparticulate approach offered a technically demanding but viable path forward.

• How Dosage Form Decisions Shape Pediatric And Geriatric Drug Development

  Developing pediatric and geriatric pharmaceuticals requires customized strategies beyond tablet crushing, balancing specific age-related palatability, packaging, real-world administration, and lifecycle management needs for optimal patient outcomes.

• When To Consider Material And Personnel Airlocks For Downflow Booths

  Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.

• The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric Solutions

  Pharmaceutical packaging must evolve alongside drug development to ensure stability, safety, and regulatory adherence, utilizing innovative designs to improve therapeutic outcomes and patient accessibility.

• Advancements In Tablet Compression Tooling: What Manufacturers Need To Know

  10/30/2025

  Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.

• Fundamentals Of Power Blending Simulations

  2/26/2025

  Predicting blending quality doesn't have to be a guessing game. Learn how to leverage virtual prototypes to make informed decisions and minimize costly trial-and-error in tablet manufacturing.

• The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators

  12/27/2024

  Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.

• Ask Us Anything: Eric Fang On Lithiation Chemistry

  7/24/2026

  Eric Fang, General Manager of Snapdragon Chemistry, on why lithiation chemistry resists batch scale-up — and how a decade spent understanding static mixing lets Snapdragon carry these reactions from milligrams to metric tons.

• Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies

  7/15/2026

  In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.