INSIGHTS ON SOLID DOSE MANUFACTURING

• HPAPI Containment: A Full Lifecycle Safety Innovation

  Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.

• How Solid-State Characterization Shapes Drug Development

  Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.

• A Brief History Of Aseptic Processing

  From Bunsen burners to advanced isolators, aseptic processing has evolved significantly. Delve into the evolution of this crucial manufacturing method, from its early sterilization techniques to today's highly controlled and regulated environments.

• Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design

  The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.

• Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery

  1/27/2025

  Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.

• Predicting Drug-Loading Limits In Tablet Formulations

  7/15/2026

  Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

• Adapting To Evolving Needs: How Modular Cleanrooms Enhance Safety In Pharmaceutical Manufacturing

  6/9/2026

  High-potency therapies demand stringent containment and worker safety. Discover how scalable, modular infrastructure simplifies compliance and protects product integrity in regulated facilities.

• Why Spray Drying Is Gaining Attention

  7/20/2026

  Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.

• Spray Dry Biologics For Oral Dosage Forms

  5/15/2026

  Spray drying enables stable oral delivery of biologics by creating protective dry powders, improving bioavailability, stability, and targeted release compared with traditional formulation methods.