INSIGHTS ON SOLID DOSE MANUFACTURING
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How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Overload Setting – Tricks And Techniques
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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Navigating OSD Formulation Development And Leveraging CDMO Partnership
Collaborating with an experienced CDMO can provide the expertise and facilities needed to navigate oral solid dose formulation complexities and ensure compliance with regulatory frameworks.
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Softgel Formulation: Addressing Stability, Shelf-Life, And Bioavailability
A CDMO that has expertise and resources in softgel formulation can help companies address stability issues, improve drug bioavailability, or ensure compliance with regulations.
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Exploring The Future Of Tablet Compression Across Emerging Industries11/18/2025
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges2/3/2025
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership In Navigating A Paragraph IV ANDA Submission6/26/2024
The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Maximize Uptime And Yield With This Feeder Base Leveling System10/8/2025
Learn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
SOLID DOSE MANUFACTURING SOLUTIONS
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Revolutionize your tablet press with the FastLok™ Die Table Surface from Natoli Engineering. Our exclusive and patented snap-in technology makes changeovers fast, easy, tool-less — getting your press back to full production in minutes.
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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If you are looking for filling systems for different products such as liquids, powder or flow-resistant highly viscous materials, Dec provides a modular concept allowing to meet a variety of packaging that is appropriate in the field of research and development as well as clinical trials. Speed up your go-to-market strategy with innovation and modular thinking.
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Unused Stokes 560 tablet press tooling, tooling size: 3650 x 7850 inch Caplet, 44 Lower Punch/44 Upper Punch/44 Die, manufactured by Natoli.
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Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.