INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-923626190-magnifying-glass-pill-tablets-powder]( "Low-Bioburden Powders For Terminal Sterilisation")
Low-Bioburden Powders For Terminal SterilisationLow‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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![GettyImages-950086574-oral-solid-OSD-pill-tablet-capsule-development]( "5 Hidden Risks In Early-Phase OSD Formulation Development")
5 Hidden Risks In Early-Phase OSD Formulation DevelopmentEarly formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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![GettyImages-2270210340-lipid-nanoparticle-delivery-system]( "Lipid Formulation Development: Why Softgels Are The Technology Of Choice")
Lipid Formulation Development: Why Softgels Are The Technology Of ChoiceLow bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
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![Aseptic Filling GettyImages-1087219366]( "A Brief History Of Aseptic Processing")
A Brief History Of Aseptic ProcessingFrom Bunsen burners to advanced isolators, aseptic processing has evolved significantly. Delve into the evolution of this crucial manufacturing method, from its early sterilization techniques to today's highly controlled and regulated environments.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
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Spray Dry Biologics For Oral Dosage Forms5/15/2026
Spray drying enables stable oral delivery of biologics by creating protective dry powders, improving bioavailability, stability, and targeted release compared with traditional formulation methods.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion2/27/2025
Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
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Achieving Licensing For A Healthcare Solution6/16/2025
Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Used Manesty 27 Station Unipress Tablet Press]( "Used Manesty 27 Station Unipress Tablet Press")
Used Manesty Unipress rotary table press, model MFG 765, 27 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, with control cabinet, up to 196,200 tablets/hour, serial# 15578 85.
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![AST innovation]( "A User-Friendly Solution For Fill-Finish Professionals")
When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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![3P Innovation - vacuum drum]( "Vacuum Drum Commercial Platform To Fill Blister Strips")
This high-output, vacuum drum commercial platform forms part of our Evolve range, designed to fill blister strips at high-speed. This unit offers a commercial scale-up from our vacuum drum development platform.
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![medoffloading.jpg]( "Containment: Offloading")
Containment solutions for the contained offloading of Aurora Filters.
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![Pharma Powder Handling]( "Pharmaceutical Powder Handling Systems")
From the incoming materials handling to the final packaging, Dec offers efficient and reliable solutions without altering product characteristics and adapted to specific containment needs.
