INSIGHTS ON SOLID DOSE MANUFACTURING
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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GLP-1 Oral Solid Dosage Workflow - Spray Drying And Tableting
Optimize containment in oral GLP-1 solid dose manufacturing. Learn how closed single-use containment and flexible isolators secure blending, spray drying, and tableting workflows.
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Optimising Solubility: Selecting The Right Technology For Early Drug Development
Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.
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HPAPI Containment: A Full Lifecycle Safety Innovation
Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.
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Safely Scaling High Potency API Manufacturing4/13/2026
Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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Benefits Of Single-Use Isolators For Cytotoxic Payload Handling6/15/2026
Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.
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Blister Solutions3/4/2025
With over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.
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Bottling Solutions3/4/2025
Explore a bottling solution that is meticulously engineered to adhere to the most stringent pharmaceutical standards, which guarantees that each product is crafted with unparalleled quality and precision.
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The Art And Science Of Pre-Picking Tablet Designs7/30/2024
Picking and sticking are the most common tablet defects that can reduce your product quality and performance. This makes perfecting the right pre-picking strategy essential to improving your processes.
SOLID DOSE MANUFACTURING SOLUTIONS
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At Natoli, we know that quality is paramount. Our cutting‐edge Precision CT Scan Service is designed to detect even the subtlest imperfections in tablets, ensuring you achieve the highest standards of quality every time.
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With our pharmaceutical tablet manufacturing capabilities, we can take your product from formulation development through full-scale commercial production.
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Our HPAPI development and manufacturing spans preclinical through commercial supply across 13 global sites, with SafeBridge-certified containment and 30 years of cytotoxic compound expertise.
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Unused Fluid Air 300 liter fluid bed dryer, model 300, 316 stainless steel contact parts, 304 non product contact, includes tower, filter system, explosion suppression system, product bowl with automatic side discharge, hydraulic bowl lifting system, spray nozzles (for possible conversion to top spray granulation), HMI and machine controls, valves, and other associated parts, serial# 10440, built 2014.
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Used 79 gallon (300 liter) Inox reactor, stainless steel construction, approximately 24" diameter x 34" straight side, dish lid top with dish bottom, jacket and interior rated 30 psi and full vacuum at 300 F, 6" top access, with (1) 4", (1) 3", (2) 2" and (2) 1.5" nozzles on top, with bottom entering magnetic agitator, .75 hp with controls, 1.5" center bottom outlet, with load cells, all on portable frame, serial# 95011-2, CRN# K82555, built 1995.