INSIGHTS ON SOLID DOSE MANUFACTURING
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Taste-Masked Dosage Forms For Pediatric Oral Delivery: An Industrial Perspective
Leveraging strategies and technologies for pediatric patient compliance for taste masking and controlled release in pharmaceutical products, enables flexibility in dosage and format options.
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Overload Setting – Tricks And Techniques
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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Functional Release Multiparticulates Slam
Review Adare Pharma Solutions’ innovative technologies and learn how these capabilities can improve patient outcomes and improve manufacturing efficiency.
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Optimizing Pediatric Product Development For Commercialization Success
Ensuring medication adherence in pediatric patients presents challenges for pharmacotherapy. Explore various dosing solutions and learn how to streamline your pediatric development journey.
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Early Development Considerations For NCE Success: Quality Systems3/1/2024
Leveraging robust quality systems can improve efficiency throughout the product development lifecycle and help companies avoid unnecessary knowledge and tech transfer, saving both time and cost.
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Round Tablet Compression Tooling — To Key Or Not To Key The Punches7/30/2024
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
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Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
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Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design11/11/2024
The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.
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Blister Solutions3/4/2025
With over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.
SOLID DOSE MANUFACTURING SOLUTIONS
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Used 19 MM APV Baker Perkins twin screw co rotating extruder, model MP-19-TC, 19 mm diameter screws, 40:1 l/d, electrically heated, water cooled barrel, split barrel design, 2 kw dc motor, 500 rpm screw spped, with Ktron main feeder, (2) Brabender auxiliary feeders, (3) Zenith melt pumps, FTS chiller, external control panel, with associated screws, screw elements, control panel, 220 volt, CE rated, APV serial# NEF990028-701/1, Baker Perkins serial# TS99535, project# 99TS196, built 1999.
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Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
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Used Cozzoli powder filler, model PF2-IS-176, stainless steel construction, incomplete unit, Allen-Bradley PLC with touchscreen interface, 115 volts, portable on casters, built 2019. As Is.
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Data acquisition and analytical and operating system software for tablet press R&D, production, and more.