INSIGHTS ON SOLID DOSE MANUFACTURING

• The Importance Of Automation For API Manufacturing: Bulk Handling, Dispensing, IBC Filling

  An operation required manual filling of IBCs by using a flexible isolator installed on an upper floor with large amounts of excipients (lactose and micro cellulose)> 100 kg and only a small amount of APls of a few kilos. Operation was strenuous due to the large quantity of excipients to be handled in the isolator which lead to the damage of the flexible isolator and containment breach. Several equipment and process changes allowed them to see an increase of plant productivity.

• Selecting Sterile API Transfer Technologies

  A CDMO was looking to solve the issue of charging sterile drug substance into a mixing tank which is a widespread problem in aseptic processing and particularly in formulation. 

• Fill-Finish Equipment For Pharma Production: SP i-Dositecno 50 VPM Isolated Line With Freeze Drying Automated

  The SP i-Dositecno 40 vial per minute line under isolation for liquid and freeze-dried products (RTU components).

• Drug Product Advancement: A Path Through Development By Powder-In-Capsule Approach

  Review best practices PIC and PIB challenges and rapid encapsulation transfer from clinic to commercial scale in these webinar slides.

• Product Development For Oral Solid Dose Using Continuous Manufacturing

  10/30/2020

  A thorough evaluation using several small-scale studies should be completed to help determine whether continuous or batch manufacturing is the best fit for your product.

• Integration Of Milling, Blending, And IBC Handling Systems For API Production

  9/1/2020

  A multipurpose facility for API production had various requirements including milling, micronizing, packaging, and the possibility to blend various batches together before or after milling. 

• Creating A Biosafety Cabinet Training Program

  3/15/2022

  This article provides information for creating your Biological Safety Cabinet (BSC) training program, a list of resources and videos, and how your BSC manufacturer could provide additional resources.

• Evaluating Your Research Equipment's Cost of Ownership

  3/22/2022

  In this paper we review how lifespan, reliability, technical support, maintenance costs and workflow efficiency factor in to calculating the cost of ownership of your research equipment.

• Dec Group Contained Powder Handling Systems

  9/2/2020

  Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.- Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.