Solid Dose Manufacturing

INSIGHTS ON SOLID DOSE MANUFACTURING

Solubility Enhancement Via Amorphous Solid Dispersions
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
Round Tablet Compression Tooling — To Key Or Not To Key The Punches
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
Harnessing Digital Twins To Optimize Tablet Manufacturing
Unlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.

Bridging The Gap Between Product Readiness And Equipment Availability
12/15/2025

Discover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership In Navigating A Paragraph IV ANDA Submission
6/26/2024

The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.
Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
6/30/2025

Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
Developing And Manufacturing Minitablets To Extend Drug Lifecycle
1/27/2025

Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
Exploring The Future Of Tablet Compression Across Emerging Industries
11/18/2025

Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.

Used K-Tron Vacuum Loading System: Series 2400

Unused Ktron vacuum loading system, Series 2400, with model 2415 receiver, with bottom mounted slide gate valve, 5 hp roots blower, and fines collector.
When The Perfect Dosage Solution Is Somewhere Between A Liquid And Tablet

Powder in a bottle is used to accelerate formulation development and introduce new chemical entities into Phase I clinical trials.
Multiparticulates For Modified Release Systems

Multiparticulates enable tailored drug release with improved flexibility, dose accuracy, and patient convenience, leveraging technologies like Diffucaps® for customized profiles including immediate, delayed, extended, and pulsatile delivery.
Quick-Release Pharmaceutical Tablet Tooling

Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.
Used 6 Station Korsch Tablet Press

Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.