INSIGHTS ON SOLID DOSE MANUFACTURING
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A Powerful Non-Destructive Tool For Tablet Characterization
Discover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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Combining Patient Centricity And Commercial Viability In Pediatric Product Development
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
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Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design
The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges2/3/2025
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Enabling Complex Phase IIa Dosing Through Flexible Clinical Packaging Design5/6/2026
Discover how flexible, patient‑centric clinical packaging supports complex Phase IIa dosing while protecting timelines, ensuring compliance, and avoiding costly primary packaging changes.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Achieving Manufacturing Efficiency In OSD Manufacturing10/16/2024
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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Predicting Drug-Loading Limits In Tablet Formulations7/15/2026
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
SOLID DOSE MANUFACTURING SOLUTIONS
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The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.
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Used Kilian rotary tablet press, model T100, 16 station, B/D IPT turret, with (8) B tooled, 16 mm diameter, 16 mm depth of fill and (8) D tooled, 25 mm diameter, 16 mm depth of fill stations in single turret, with additional 9 station IPT B toolded turrent, 42 Kn pre-compression, 65 Kn main compression, keyed upper punch guides, singled sided with force feeder, commission# 706849, built 2002.
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Isolators with product protection as a housing for aseptic processes, e.g. filling, loading and unloading of freeze dryers.
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Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs. Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.
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Used Fitzpatrick Chilsonator roller compactor, model 1.5LX8D, with 8" diameter x 1.5" wide grooved rolls, vertical and horizontal pre-compression screws, serial# 489.