INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-186750891-Isolator]( "The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators")
The Crucial Role Of Cleaning In Effective VPHP Decontamination For IsolatorsEffective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.
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![3P Innovation - isolator]( "Engineering Challenges Of Designing Pharmaceutical Isolators")
Engineering Challenges Of Designing Pharmaceutical IsolatorsDesigning pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
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![GettyImages-1208573753-scientist-fizz-solubility-lab-glass]( "Improving API Solubility Using Hot Melt Extrusion Formulation")
Improving API Solubility Using Hot Melt Extrusion FormulationSolubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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![GettyImages-163720603 tablet press, OSD]( "Segments: Next-Generation Tablet Press Technology")
Segments: Next-Generation Tablet Press TechnologySegments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
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Developing And Manufacturing Drugs With HPAPIs1/27/2025
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines1/15/2026
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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A Solvent-Free, Fusion-Based ASD Manufacturing Process3/5/2024
Explore a solvent-free alternative for the production of amorphous solid dispersions (ASDs) that not only improves manufacturability but also reduces the carbon footprint of ASD manufacturing.
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The Role Of Quality By Design In Pharmaceutical Tablet Development7/30/2024
Quality by Design (QbD) ensures efficiency and high standards in pharmaceutical tablet development. Explore how this proactive approach transforms manufacturing processes and enhances product quality.
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Isolators For Pharmacy Compounding – Time For Change?3/14/2025
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
SOLID DOSE MANUFACTURING SOLUTIONS
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![79 Gal Inox Reactor]( "Used 79 Gallon Inox Reactor")
Used 79 gallon (300 liter) Inox reactor, stainless steel construction, approximately 24" diameter x 34" straight side, dish lid top with dish bottom, jacket and interior rated 30 psi and full vacuum at 300 F, 6" top access, with (1) 4", (1) 3", (2) 2" and (2) 1.5" nozzles on top, with bottom entering magnetic agitator, .75 hp with controls, 1.5" center bottom outlet, with load cells, all on portable frame, serial# 95011-2, CRN# K82555, built 1995.
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![GettyImages-1311641109-capsule-tablet-pill-OSD-oral-solid]( "Oral Solid Dose Formulation And Lab Scale Capabilities")
Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
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![Dec Group Sterile Process small]( "Overcoming Aseptic Manufacturing Challenges To Prevent Contamination")
The pharmaceutical industry has steadily moved to increased production and handling of sterile highly potent active ingredients (HPAPIs). Dec’s containment technologies comply with pharmaceutical quality manufacturing standards and are available for aseptic operations.
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![Used Bellatrx Pharmaceutical Tablet Counter]( "Used Bellatrx Pharmaceutical Tablet Counter")
Used BellatRx electronic lane counter, model RX-Fill PLUS, speeds up to 25 bottles/minute at 100 count, 2-40mm tablet size, 1" - 4" by 12" high bottle size, 0.5" or larger neck diameter, Allen Bradley PLC controls with PanelView 600 HMI, 120 volt, order# 7155, serial# 035, built 2019.
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![Fitzpatrick Chilsonator]( "Used Fitzpatrick Roller Compactor: Chilsonator: 1.5LX8D")
Used Fitzpatrick Chilsonator roller compactor, model 1.5LX8D, with 8" diameter x 1.5" wide grooved rolls, vertical and horizontal pre-compression screws, serial# 489.
