INSIGHTS ON SOLID DOSE MANUFACTURING
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![cdmo-solid-dose-GettyImages-1432665138]( "The Importance Of Polymorph Screenings")
The Importance Of Polymorph ScreeningsDiscover how systematic polymorph screening reduces development risk, safeguards product performance, and enables confident solid‑form selection across the drug development lifecycle.
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![Adare-2]( "Layer By Layer: 3D Screen Printing And The Future Of Drug Development")
Layer By Layer: 3D Screen Printing And The Future Of Drug Development3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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![KinetiSol Amorphic Dispersions]( "Solvent-Free, Fusion-Based Amorphic Dispersion Process")
Solvent-Free, Fusion-Based Amorphic Dispersion ProcessDiscover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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![GettyImages-1669461851 tablet manufacturing]( "Achieving Manufacturing Efficiency In OSD Manufacturing")
Achieving Manufacturing Efficiency In OSD ManufacturingGain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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Benefits Of Single-Use Isolators For Cytotoxic Payload Handling6/15/2026
Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production8/15/2025
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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Technologies And Patient-Centric Solutions7/18/2024
Our innovative technology platforms, including Taste Masked Microcaps® and Optimµm®, address issues like taste masking, swallowability, and controlled release to improve patients' quality of life.
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Die Bore Cracking: How To Achieve Reliable Tablet Production7/30/2024
Die bore cracking is a significant issue in tablet manufacturing, affecting the quality of the tablets and potentially damaging the tablet press. Explore how to analyze for and prevent this damage.
SOLID DOSE MANUFACTURING SOLUTIONS
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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![GettyImages-1127105013-lab-computer-research-scientist]( "Solid Form Services")
We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.
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![16 Quart P-K twin shell Blender]( "Used Patterson-Kelley Twin Shell Pharmaceutical Blender")
Used 16 quart Patterson Kelly twin shell Blendmaster blender, 1 6 quart stainless steel shell, rated 200#/cu ft max material density, serial# C419381.
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![K-Tron Powder Delumper Hopper]( "Used K-Tron Powder Delumper Hopper")
Used K-Tron powder delumper hopper, stainless steel construction, with .5 hp, 230/460 volt motor drive with VFD controllers.
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![Dec 2]( "Pharmaceutical Filling And Packaging Lines")
Dec’s ability to provide end-to-end solutions from API manufacturing to primary packaging filling covers the complete range from R&D processes and small batches to large filling campaigns. Our solutions include state of the art robotics for the filling and handling of complex delivery systems like pre-filled syringes (PFS).
