INSIGHTS ON SOLID DOSE MANUFACTURING
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Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability
Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.
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Enabling Complex Phase IIa Dosing Through Flexible Clinical Packaging Design
Discover how flexible, patient‑centric clinical packaging supports complex Phase IIa dosing while protecting timelines, ensuring compliance, and avoiding costly primary packaging changes.
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Low-Bioburden Powders For Terminal Sterilisation
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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Safely Scaling High Potency API Manufacturing
Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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Innovations, Solutions, And USP <1062> With Scale Up11/4/2025
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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A Simple And Powerful Solution For Accelerating Dissolution5/5/2026
Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets1/27/2025
Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.
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How To Fast-Track Your Oral Solid Dose To Phase 12/17/2026
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
SOLID DOSE MANUFACTURING SOLUTIONS
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The production and handling of highly potent sterile APIs within a multi-purpose designed plant are becoming more and more prevalent within the pharmaceutical industry.
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With ample available capacity, Ropack Pharma Solutions provides the efficiency of five bottling lines with quick changeovers, online validated fill accuracy and the flexibility to accommodate small lots to commercial runs for the bottling of tablets, capsules and powders.
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Unused 600 liter GEA high shear mixer, model PMA 600 Advanced, 316L stainless steel product contact surfaces, 240-450 liter working capacity, 36 kw main impeller, 1-170 rpm, 11 kw chopper, 1000-3000 rpm, jacketed bowl, machine designed to 16 bar shock rating, full vacuum rated bowl, 8" side discharge with valve, integrally mounted Quadro Comil, model U20, integrally mounted blade hoist, associated control systems with Allen Bradley plc and HMI designed for class 1 div 2 area, 480 volt, with GEA temperature control unit, model PMS 600, WIP design, through the wall design mounted on base with PL600 IBC hoist with (4) approximately 750 liter IBC's, PMA 600 Advanced serial# 14369.1310, built 2015 and unused.
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Dec provides unique solutions to charge process equipment such as reactors, mixing vessels or dryers in a fully safe manner eliminating the need to connect the isolator directly to the equipment to be charged or to install the isolator on an upper floor. A single isolator system can be used for multiple vessels charging.
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Antibody‑drug conjugate services support development from early clinical stages through commercial manufacturing with integrated analytics, containment expertise, and scalable conjugation capabilities.