INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Sterility testing isolators with product protection for the sterility test under aseptic and optionally aseptic/toxic conditions. A Rapid Decon Hatch (RDH) can be connected as an option.

  • Thanks to its weighing terminal IT 9000 as well as its dosing device Multi-Dosimat, JetSolutions SA offers reliability and precision for filling powders or granulates into IBCs, boxes, bags, trucks, etc.

  • Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

  • Handling today’s higher-potency active pharmaceutical ingredients (HPAPIs) presents ever-increasing regulatory concerns — especially within manufacturing-area isolators and lab areas, and for flexible GMP chambers where airflow, temperature, humidity and pressure differentials exist from room to room.

    The JetVent™ system’s precise fan speed delivers accurately controlled negative air pressure to ensure proper flow into flexible-wall isolators, while reducing the risk of worker exposure.

  • ROSS Ribbon Blenders efficiently mix powders, granules, and bulk solids across industries, offering customizable lab-to-production models for various bulk densities, including heavy-duty and sanitary applications.