INSIGHTS ON SOLID DOSE MANUFACTURING

  • GLP-1 OSD Chemical Synthesis Workflow

    Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.

  • Patient Adherence With A Novel Dosage Form

    A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.

  • Improving API Solubility Using Hot Melt Extrusion Formulation

    Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.

  • Why Spray Drying Is Gaining Attention

    Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.

SOLID DOSE MANUFACTURING SOLUTIONS

  • Unused Stokes 560 tablet press tooling, tooling size: 3650 x 7850 inch Caplet, 44 Lower Punch/44 Upper Punch/44 Die, manufactured by Natoli.

  • We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.

  • Isolators with product protection as a housing for aseptic processes, e.g., filling, loading and unloading of freeze dryers.

  • Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.

  • Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.