INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Master the art of tablet manufacturing with our comprehensive hands-on seminar, designed to equip you with in-depth knowledge and skills required for pharmaceutical and supplement manufacturing. This two and a half-day course covers essential topics such as tablet press setup, powder preparation, formulation, excipients, API, direct compression, wet granulation, dry granulation, tablet press operation, compaction, lubricants, and quality control.

  • Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.

  • Setting a New Benchmark for Ease of Operation

    The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.

    With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.

  • Personal protection pharmaceutical isolators enables personal protection for operators when handling toxic substances.

  • Basic Powder Flow Characterization [USP <1174>]:

    A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.

    Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.

    When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.