INSIGHTS ON SOLID DOSE MANUFACTURING
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
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Rheological Properties Of Pharmaceutical Excipients: Lactose Monohydrate And Carboxymethyl Cellulose
Explore lactose monohydrate and CMC rheology, highlighting their flow, cohesion, and compressibility properties to optimize pharmaceutical formulations under varying stress and temperature conditions.
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High Potency APIs And The Evolving Demands Of Drug Development
See how higher API activity is changing expectations around containment, scalability, and cross‑functional alignment — and why early decisions now have a greater impact on long‑term success.
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Advancements In Tablet Compression Tooling: What Manufacturers Need To Know
Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
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Decontamination Of Aseptic Pharmaceutical Isolators Using Vaporized And Aerosolized Hydrogen Peroxide8/26/2026
Aerosolized hydrogen peroxide decontamination cuts isolator cycle times from 70 to 15 minutes while drastically reducing biocide and overall energy usage.
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Liquid Suspension Trends In The CDMO Space1/15/2026
Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
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Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months2/26/2026
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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Achieving Licensing For A Healthcare Solution6/16/2025
Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications8/31/2026
More than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
SOLID DOSE MANUFACTURING SOLUTIONS
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Mikart offers a wide range of bottle filling options personalized to your needs.
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Handling highly potent active pharmaceutical ingredients safely requires precise pressure control and automated breach response that many facilities struggle to maintain consistently.
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A structured overview of a Phase I oral solid dose development solution promising GMP clinical batch delivery in 25 weeks from API receipt, with defined scope and flexible options.
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This high-output, vacuum drum commercial platform forms part of our Evolve range, designed to fill blister strips at high-speed. This unit offers a commercial scale-up from our vacuum drum development platform.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?