INSIGHTS ON SOLID DOSE MANUFACTURING
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A Technology Driven CDMO & Trusted Manufacturing Partner
Whether it's through extended release formulations or titratable dosage forms, we are dedicated to addressing the specific needs of different patient populations, including pediatrics and geriatrics.
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Combining Patient Centricity And Commercial Viability In Pediatric Product Development
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
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An Alternative Method Of Drug-Excipient Characterization
Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
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Safely Scaling High Potency API Manufacturing
Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
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Powder Rheology: Gateway For Tablet Sticking Insights10/7/2025
Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing6/30/2025
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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6 Strategic Pillars For Selecting A Drug Packaging Partner4/14/2026
Early engagement with an expert packaging partner supports safe, cost-effective drug development and logistical success from precommercial stages through full market launch.
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Low-Bioburden Powders For Terminal Sterilisation2/24/2026
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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Lower Punch Tip Bending / Buckling11/11/2024
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
SOLID DOSE MANUFACTURING SOLUTIONS
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Dec‘s philosophy is to develop customer-specific modules and equipment. Starting with agreed project scope, intensive brainstorm sessions, strong design processes and (customer) reviews, the aim is to deliver an innovative filling solution. During the concept development, risk analysis is an important tool in the decision-making process.
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Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.
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Used GEA Mobile Minor Spray Dryer, Model MM-PSR, stainless steel construction, 0.8 meter diameter chamber, GEA Niro nozzle atomixer, cone bottom, with top expansion chamber, with inlet HEPA filter housing, cyclone fines collector, discharge filter housing, and .95 kw blower, control panel with Allen Bradley Panelview1500 HMI, project# 1093-2412, built 2017.
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The NP-RD10A fits on benchtop areas and is constructed with an electro-less nickel frame. Using this tablet press in lab research significantly helps to improve tablet uniformity, reduce trial-and-error, decrease formulation waste, and save valuable time and effort.
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With our pharmaceutical tablet manufacturing capabilities, we can take your product from formulation development through full-scale commercial production.