INSIGHTS ON SOLID DOSE MANUFACTURING

• Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric Oncology

  When an oral liquid formulation of crizotinib failed pediatric trials due to intolerable taste and irritation, a multiparticulate approach offered a technically demanding but viable path forward.

• How To Handle Intrinsic Product Powder Particles

  Powder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.

• Delivering API-In-Capsule For Potent, Low-Flow Compounds

  See how an automated capsule-filling approach addressed poor-flow APIs, improved operator safety, and supported fast scale-up for clinical supply needs.

• Practical Formulation Strategies For Poorly Soluble APIs

  Poor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.

• Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation

  8/20/2026

  Explore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.

• Low-Bioburden Powders For Terminal Sterilisation

  2/24/2026

  Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.

• Exploring The Future Of Tablet Compression Across Emerging Industries

  11/18/2025

  Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.

• Improving Stability Through Science-Led OSD Reformulation

  10/13/2026

  A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

• Maximize Uptime And Yield With This Feeder Base Leveling System

  10/8/2025

  Learn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.