INSIGHTS ON SOLID DOSE MANUFACTURING
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
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Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability
Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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A Simple And Powerful Solution For Accelerating Dissolution
Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.
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How Is Peptide Crystallization Screening Used In Peptide-Based Therapeutic Development?7/24/2026
Hannah McLachlan, Project Scientist IV at Cambrex Edinburgh, on what crystallization screening delivers for peptide therapeutics — more stable material, higher purity, and a molecule clients can store without specialist infrastructure.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines1/15/2026
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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An Alternative Method Of Drug-Excipient Characterization12/30/2024
Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
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Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion2/27/2025
Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
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How To Fast-Track Your Oral Solid Dose To Phase 12/17/2026
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
SOLID DOSE MANUFACTURING SOLUTIONS
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Each service visit will include the following:
- Preventative Maintenance
- Equipment inspection (paddle feeder, tachometer, cams, compression rollers, etc.)
- Turret inspection
- Additional Operator and Technician Training
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Establish safe barrier protection in minutes with a portable benchtop isolator. Secure containment for hazardous materials or inert gas processing across flexible laboratory scales.
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Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.
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Open RABS as a housing for aseptic processes, e.g., filling, loading, and unloading of freeze dryers. Product protection is achieved by a barrier (oRABS housing with gloves) between the operator and the product.
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Handling today’s higher-potency active pharmaceutical ingredients (HPAPIs) presents ever-increasing regulatory concerns — especially within manufacturing-area isolators and lab areas, and for flexible GMP chambers where airflow, temperature, humidity and pressure differentials exist from room to room.
The JetVent™ system’s precise fan speed delivers accurately controlled negative air pressure to ensure proper flow into flexible-wall isolators, while reducing the risk of worker exposure.