Application of the LIGHTHOUSE headspace method demonstrates how ability to quickly and accurately determine headspace oxygen levels saves time and enables deep insight into formulation stability.
Engineering is a process to develop a design to solve a problem. In the world of containment engineering, careful premeditation is important to the completion of a successful engineering project.
In pharmaceutical formulating the elements are often not fully compatible and must be mixed following a strict procedure to obtain a stable and durable structure. This task is even more challenging when formulating with natural ingredients. The constant need to create new formulations or reformulate existing formulations requires thorough monitoring of formulation properties. This article outlines the crucial steps to be considered for a full and complete characterization of your formula.
This application note describes how laser-based headspace analysis is used for the rapid non-destructive determination of headspace oxygen levels in pre-filled syringes. Data is presented demonstrating two major applications of this technique: 1) headspace oxygen monitoring on a pre-filled syringe line filling oxygen-sensitive product, and 2) container closure testing of pre-filled syringes.
Frequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out.
This paper provides an introduction to particle sizing comparing six widely used techniques, explaining how they work and what this means in terms of strengths and limitations.
This paper takes an introductory look at the techniques used to investigate porosity, the data generated and their strengths and limitations for specific materials, covering more complex approaches such as the Reverberi method and the application of non-local density functional theory (NLDFT) to illustrate the necessity for, and potential benefits of, more advanced analysis.
This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process. Additionally, when highly potent active pharma ingredients are not effectively contained, workers may be adversely affected.
This webinar describes how non-destructive headspace moisture analysis can be used for characterizing batch moisture distributions, for lyo cycle development and optimization, and for freeze dryer moisture mapping and validation.
Nitto Avecia Pharma Services is a premier contract development and manufacturing organization offering a comprehensive range of cGMP services including formulation development, parenteral manufacturing, and a complete package of CMC analytical services for small to large molecules and nearly all dosage forms
The In-VitroCell ES (Energy Saver) NU-5810 Microbiological CO2 Incubator features a 145°C dry sterilization cycle and 95°C humidified decontamination cycle as an added defensive against incubator contamination providing an optimal controlled environment for cell growth
Flow Sciences, Inc. (FSI) evaluates and ensures that every enclosure shipped to their customer meets all relevant standards. FSI performs procedures from the American Society of Heating, Refrigeration, and Air Conditioning Engineers (ASHRAE) 110-2016 – Methods of Testing Performance of Laboratory Fume Hoods.
With the AMI and its optical emission spectroscopy Pfeiffer Vacuum has introduced a method with lower detection limits compared to any other method that uses gas trapped in the cavity.
With over 10 years industry experience per structural scientist, Nitto Avecia Pharma Services’ strategic, systematic approach provides high quality solutions for identification, characterization, and development of highly sensitive methodologies.