INSIGHTS ON QUALITY CONTROL

• Complete Quality Control With Rotational Viscometry Applications

  To ensure a consistent flow of material during production, Anton Paar has designed the ViscoQC 300, a multi-point viscosity measurement tool for achieving outstanding results in viscosity determination.

• Dimerization Of Bovine Serum Albumin As Evidenced By Particle Size And Molecular Mass Measurement

  Preparation methods have a large influence on the folding and oligomerization behavior of proteins in solution. Read how a useful tool can be used for the optimization of sample preparation and the quality control of proteins.

• Characterization Of Exosomes Isolated From Cell Culture Media

  Exosomes are intensively studied as potential drug delivery vehicles. Here we demonstrate that the Litesizer™ 500 can efficiently characterize exosome particle size, and that this criterion can be used to monitor exosome stability in vitro.

• How To Understand ASTM E2500

  ASTM E2500 introduced the term “verification” but was essentially silent on the idea of “commissioning” and the term “qualification.” ASTM is a minimum standard, and teams are free to go beyond this minimum as long as the basic provisions are met. There are four basic approaches in the industry currently.

• Upstream Considerations For Biosimilar Development

  Understanding upstream challenges during biosimilar development and creating a strategy to overcome them is critical for ensuring a high chance of success with your biosimilar product.

• Master The Flow: Viscometry & Rheometry Meters

  Your sample is our challenge. Let us find the right viscometer or rheometer for you.

• Headspace Gas Ingress Testing For CCI

  Imagine a blue dye test, but replace the dye with a tracer gas. Headspace Gas Ingress Testing is a robust detection method of critical leaks. It is a rapid, non-destructive, analytical measurement and can be scientifically validated. Are you considering to upgrade your blue dye test, and do you want to learn more about this approach? Watch this webinar.

• Water Activity Measurements And Microbial Contamination In Pharmaceutical Products

  Non-sterile pharmaceutical products are subject to microbiological examination prior to release and during stability testing. While the tests described in these chapters cannot be eliminated from protocol completely, USP <1112>, Application of Water Activity Determination to Nonsterile Pharmaceutical Products, suggests that water activity determination can be used to reduce the need for frequent microbial limit testing and screening.

• Determining CCI During Deep Cold Storage

  When working on live viral vaccines, gene therapies or product that contains active cells cold storage is often required to maintain stability and/or activity. Deep cold storage, at dry ice (-80°C) or even cryogenic (-196 °C) temperatures, poses a significant challenge to packaging components and can result in CCI failures. Watch this webinar for a detailed presentation on this topic.