• Virus Safety For Continuous Processing

    Transitioning to a continuous processing approach requires the implementation of an effective virus clearance strategy, which is intended to prevent various virus contaminations that could threaten patient safety.

  • Cleanroom Manufacturer Expands Capacity To Meet Industry Needs

    AES Clean Technology builds more cleanrooms than anyone else. The market is busy, and so are we... but are we too busy? The answer is a resounding "NO, AES is not too busy!" We plan our cleanroom design, panel manufacturing, and manpower loading and scale as needed. We currently have the capacity to more than double our panel manufacturing.

  • Dancing In The Bioprocessing Ballroom: Voices Of Experience

    Single-use technology is well-established and made its way into commercial licensed facilities, but there is more innovation in this field which will enhance its versatility into new markets and technologies.

  • 6 Misconceptions About Automating Cell Therapy Manufacturing

    To help you move into a digitized world, here are six common misconceptions that can potentially hinder your ability to successfully execute an MES for cell therapy.

  • Chromatography Scale-up: Don’t Get Tied Down By Bed Height

    When scaling, you can make better use of existing chromatography columns while avoiding overcapacity. Try this alternative approach to achieve a constant residence time.

  • Three Options To Viral Vector Manufacturing Capacity

    A recent Virtual Think Tank focused on the challenges and trends influencing design considerations for viral vector manufacturing facilities, and how they can impact companies developing cell and gene therapies.

  • Feeder Advancements Improve Cleanability And Automation

    This webinar is designed to educate the attendee of the newest criteria and engineered solutions available in feeding and material handling for quick and efficient product changeover.  Learn from the experienced expert how automated feeders and components in Clean-in-Place (CIP) or Wash-in-Place (WIP) designs can improve downtime for cleaning, minimize waste, and improve overall process quality.

  • Cleanroom Design Cost Control

    Find out how you can control costs on your cleanroom project with Nicholas Vermont ,Director of Estimating from AES Clean Technology.

  • AES Clean Technology Career Opportunities

    AES Clean Technology provides industry-leading modular clean room facilities with career opportunities in design, manufacturing, installation and sales. Hear how our current employees came on board to AES and what they enjoy about their careers.


  • Clean And Disinfect For Viruses And Other Pathogens

    Per Center for Disease Control (CDC) guidelines for cleaning and disinfecting viruses and other pathogens, any form of disinfection necessarily follows cleaning.  The process of cleaning will remove any residues that might shield any virus or pathogen from the disinfection step that comes next.  Disinfection, following the thorough cleaning and rinsing, can be done with bleach solutions, 70% alcohol solutions, or other products with EPA-approved emerging viral pathogens claims.  As outlined by CDC, bleach solutions should reside on surface for at least one minute and can be made as follows:

    • 5 tablespoons (1/3rd cup) bleach per gallon of water, or
    • 4 teaspoons bleach per quart of water

    An excellent cleaning and wiping solution can be made with 0.5% (0.75- 1.5 oz/gal or 5 mL/L) Alconox® Powdered Precision Cleaner or Liquinox® Critical Cleaning Liquid Detergent, depending on preference for powder or liquid concentrate, respectively. Following which, per the CDC guidelines, wipe with the above bleach solution or other disinfectant solution. Allow wiped down surfaces to sit for several minutes before rinsing to complete the disinfection.

  • SP Hull Vial Washers

    Effective and Efficient Vial Washing
    Vial washing cleans the vials of particulate matter and microorganisms; however traditional vial washers have many moving parts, which can themselves generate particulates. SP Hull vial washers have just two moving parts in their washing chamber to ensure highly effective cleaning and their main drive is servo driven. Each vial format has a Human Machine Interface (HMI) selected recipe with specific settings for spray time to help reduce water consumption. Vials are washed without the washing needle entering the vial, thereby eliminating the risk of vials being damaged due to misaligned or bent washing needles.

  • Pre-Designed Pharmaceutical Cleanrooms: Faciliflex Express

    Express is a pre-designed pharmaceutical cleanroom solution that delivers a commissioned cleanroom in as little as 6 months. Pre-designed standard pharmaceutical cleanroom layouts are the next generation for snap together installation of modular panel systems. Faciliflex Express has 3 models 5k, 15k, and 30k representing cleanrooms of approximately 5,000, 15,000, and 30,000 square foot. Each model is a fully integrated solution and includes design, material, HVAC, and installation.

  • Biological Safety Cabinets: Class I And Class II

    NuAire Biological Safety Cabinets provide personnel, product and/or environmental protection when looking to obtain optimum control over product quality while reducing the potential for exposure. Ergonomic Biosafety Cabinet design improves laboratory safety practices and process accuracy.

  • Pharmaceutical Cleanroom Design Services

    Your next cleanroom is more akin to a piece of equipment than a room. Operational efficiencies, compliant flow of materials and personnel, and lifecycle considerations should dictate the selection of your cleanroom partner. AES designers have been engineering functional cleanroom facilities for over three decades, guaranteeing the performance of each and every facility. Our in-house designers work as a team with our cleanroom construction personnel to engineer a cost-effective project while maximizing performance, value, and constructability. The greatest value is realized when AES is integrated into the design team at the start of the project. Early project integration with the AES experts helps the infrastructure team decide what support and cleanroom solutions the clean space requires. Early participation by AES saves design costs, expedites schedule, and eliminates a duplication of services.


Learn how to employ science-, risk-, and statistics-based approaches to cleaning and cleaning validation at your facility with this free, 100-page e-book, written by a global team of cleaning validation experts, pharmaceutical toxicologists, statisticians, and Six Sigma professionals.