INSIGHTS ON PHARMACEUTICAL INSPECTION

  • Dual-Lane Checkweigher Provides High-Throughput Tube Line Automation Inspection

    Teligent produces a diverse range of generic prescription topical and injectable pharmaceuticals. To automate inspection on their high-throughput tube line, they turned to a checkweigher with a two-lane configuration that matches their dual-lane filler.

  • The Introduction To High Voltage Leak Detection (HVLD) Technology

    It is understood that no matter how carefully a product has been prepared, it would still be unsafe for human use if the container has a pinhole, a crack or a defective seal. There are a variety of methods widely used in the detection of pinholes, cracks and defective seals in containers however a majority are destructive causing the loss of good product and packaging components. Read more to learn why the High Voltage Leak Detection (HVLD) system is totally free from these shortcomings and has additional advantages for ensuring seal integrity.

  • The Importance Of Package Integrity To Shelf Life Of Products

    The importance of Package integrity as it relates to protecting a product’s shelf life from manufacturing, through transportation to the consumer or patient. This video will discuss the importance of protecting package contents from critical contaminants – namely oxygen, moisture and bacteria. The challenges associated with transportation will be reviewed and specifically how altitude and latitude affect various packaging formats when packaging defects are present.

  • The Importance Of Package Integrity To Shelf Life Of Products

    Pharma Tech Industries (PTI), a contract manufacturer and packer of pharmaceuticals, medical devices and personal care products, is focused on exceeding customers’ expectations. They rely on x-ray, metal detection systems and checkweighers to consistently achieve their high quality standards

  • A Science-Based Approach For Ensuring Container Closure Integrity Of Sterile Vials

    Recent regulatory guidance has triggered changes in industry best practices in the area of container closure integrity (CCI) testing. A more science-based holistic approach that includes robust design & qualification of the process and the implementation of appropriate process controls is required. This webinar will describe a framework to enable such a holistic approach to CCI that assures both the primary packaging and the process contribute to good CCI of sterile injectable vial product.

  • Automated Inspection System For CCIT Of Parenteral Drug Products: Veripac LPX

    The VeriPac LPX from PTI is the next generation automated inspection system for container closure integrity testing of parenteral products. This product features automated CCI for prefilled syringes and vials using PTI’s vacuum decay technology.  The VeriPac LPX features a dynamic design tailored to fit your production requirements.

  • Generating Robust Residual Seal Force-CCI Correlation Data To Ensure CCI Of Vials Requiring Deep Cold Storage

    The increased implementation of deterministic analytical methods for container closure integrity (CCI) testing has enabled deeper insight into the performance of primary packaging with respect to CCI. However, ensuring good CCI of sterile injectable product goes beyond CCI testing during the product life cycle. This case study describes how packaging development and process study data of a pharmaceutical vial product requiring deep cold storage can be combined in a holistic approach.

  • Oxygen Sensitive Product: Comparing Oxygen Testing Methods

    The accurate determination of oxygen concentration as a critical quality parameter for oxygen-sensitive products is important across the product life cycle activities. Traditional methods for determining headspace oxygen levels in parenteral containers, such as electrochemical methods or gas chromatography, are slow and destructive. This article describes several case studies comparing non-destructive laser-based oxygen headspace analysis with electrochemical oxygen analysis and gas chromatography.

  • Inline Weighing Technology Offers Additional Quality Check Features

    Protina Pharmazeutische GmbH produces high-quality preparations, such as medicine, food supplements and cosmetics. Alongside weight monitoring, the checkweigher used at Protina offers other important functions that support the company's system of strict quality management.

PHARMACEUTICAL INSPECTION SOLUTIONS

  • Pharmaceutical Contract Packaging: Quality And Technologies

    Our cutting-edge technology and impeccable standards ensure that our customers receive products that meet their exact needs.

  • Pharmaceutical Metal Detection Systems: Tablets & Capsules

    Designed to meet the exacting standards and regulations of the pharmaceutical industry, METTLER TOLEDO Safeline pharmaceutical metal detectors provide the ultimate solution in fully integrated product inspection and rejection systems for tablets, capsules, powders and granules. Our metal detection systems are designed to detect all metal contaminant types, including ferrous, non-ferrous and even the most difficult-to-detect non-magnetic stainless steels.

  • X-Ray Systems: Inspection Of Tall, Rigid Containers

    The X37 Series offers the most technically advanced x-ray inspection system on the market for tall, rigid containers. The X37 Series provides the customer with the tools to achieve compliance with industry standards such as HACCP.

  • Non-Destructive, Non-Subjective Package Testing: VeriPac System

    VeriPac systems can be easily integrated into the packaging process to improve quality, reduce waste, and provide operators with a clear understanding of package quality. VeriPac test systems are non-destructive, non-subjective and require no sample preparation. Test fixtures are designed to inspect flexible, rigid and semi-rigid packaging. VeriPac inspection systems use cutting edge innovation to provide repeatable, more sensitive, and more robust detection of defects.

  • Helium Leak Detection For Combination Drug Products

    There have been many advances over the past decade in terms of drug product delivery methods. As a result, key developments like unique cartridge based delivery systems have become common. It is well documented that Helium mass spectrometry is most suited for non-porous packaging such as vials and syringes. The same methodology can also be applicable to cartridge based delivery systems. In most cases the key to success is the development of a text fixture device designed and manufactured to the specific cartridge system being testing. These custom fixtures for helium leak detection can be designed to isolate specific areas of interest in the cartridge system.