Freeze Drying Process Development

This video illustrates a comprehensive moisture mapping study performed on a freeze dryer that aims to enhance both the efficiency of the freeze-drying cycle and the overall performance of the equipment. During the study, a batch of vials undergoes a complete freeze-drying process, after which the residual moisture levels within the vials are meticulously analyzed. A key feature of this approach is the use of a LIGHTHOUSE non-destructive headspace analyzer, which enables rapid and accurate moisture mapping without compromising the integrity of the samples. This advanced analytical technique allows for efficient cycle optimization and ensures consistent control over residual moisture levels. By visualizing the impact of process adjustments in real time, the study demonstrates how targeted interventions can lead to more reliable and efficient freeze-drying operations.