INSIGHTS ON PHARMACEUTICAL PRODUCTION

  • Digital Manufacturing Of Biologics

    In addition to an explanation of digital manufacturing, this paper covers how it can improve the productivity and robustness of existing processes and facilities. 

  • Key Considerations When Selecting A Manufacturing Execution System

    For the last two decades, Manufacturing Execution System (MES) has been a hot topic at nearly every automation conference and for good reason. MES is a powerful tool that can deliver process efficiencies, yield improvements, cost avoidances, right first time, and much more.

  • Tips For Viral Vector Production

    The viral vector market continues to grow, and the increased interest in improvements in manufacturing technologies is driven by recent approvals in cell and gene therapies. These scalable and cost-efficient processes for GMP manufacturing environments address viral vector manufacturing challenges.

  • A Faster Path From Pre-Filled Syringe To Auto-Injector

    This on-demand webinar covers how to transition your self-administration product from pre-filled syringe to auto-injector more quickly with an experienced partner who can anticipate equipment and process needs.

  • Product Development For An Oral Solid Dosage Using Continuous Manufacturing

    A thorough evaluation using several small-scale studies should be completed to help determine whether continuous or batch manufacturing is the best fit for your product.

PHARMACEUTICAL PRODUCTION SOLUTIONS

  • BIOSTAT® RM TX Single-Use Bioreactor

    New wave mixed system developed specifically for closed, automated expansion of consistent quality cell products such as ex vivo cellular immunotherapies.

  • HyPerforma Glass Bioreactors

    The Thermo Scientific™ HyPerforma™ Glass Bioreactors are available in 1, 3, 7, and 15 L sizes. They offer easy operation and rapid assembly and are manufactured with the highest standards for materials and surface finish. Developed using a computational fluid dynamics (CFD) simulator, the HyPerforma Glass Bioreactor impellers provide maximum mixing with minimum shear force, resulting in a higher average kLa. The cold finger has been replaced by a cooling loop to increase the thermal surface. Laboratory performance tests have demonstrated a cooling rate two times better than a sample of products from other suppliers. Control can be bidirectional, which allows a single-wall vessel to be used for mammalian applications and fermentation processes* (needs two kits).

  • Used 1200 Liter Collette High Shear Mixer

    Used Collette high shear granulating mixer, model GRAL1200, 316L stainless steel construction, rated 7 bar internal, 3 blade main agitator with 55 KW (73 HP) motor, hydraulic bowl raise/lower mechanism with 5 KW (6.7 HP) power pack on base, side discharge with pneumatically operated plug valve with controls, serial# 97GR112000018, built 1998.

  • Saltus® Single-Use Mixing System Brochure

    Saltus® mixing systems are based on a design philosophy which emphasizes usability and automation. From the easy to install, self-deploying, single-use mixing assembly to the fully automated, one-button start of the control system, Saltus® mixers provide unparalleled usability and ease of operation.

  • Validation Guide: Flexsafe® Bag For LevMixer® And Flexsafe® Bag For Magnetic Mixer

    Single-use mixing systems are increasingly used in the manufacture of biopharmaceutical products as they allow biopharmaceutical companies to realize the benefits of single-use technology throughout the process.

    Flexsafe® for Magnetic Mixer1 offers powerful mixing performances for media and buffer formulation. Flexsafe® for LevMixer®2 offers low shear mixing performances for homogenization, viral inactivation and formulation of sensitive drug substances and drug products.