INSIGHTS ON PHARMACEUTICAL PRODUCTION

• Process-Economy Simulation Of mAb Capture Step With Protein A Chromatography Resin

  Calculation examples that highlight scenarios where the enhanced capacity and alkaline‑stability of MabSelect PrismA can provide process economic benefits to large‑scale mAb processing.

• Evolution Of Single-Use Bioprocessing Into BioPharm 4.0

  Biopharma manufacturers seek dynamic processing economics that address the paradigm shift from blockbuster drugs with established production schemes to small-scale manufacturing and innovative tech.

• Bioprocess Plant Cuts Down Time With Self-Calibrating Temperature Sensor

  To keep the risks in bioproduction as low as possible, an increase in calibration frequency is required. Read how the self-calibrating iTHERM TrustSens temperature sensor kept downtime to a minimum.

• Utilizing External Collaboration To Accelerate Vaccine Development

  Securing a partner to serve as an extension of Janssen’s Biotherapeutics Development API-Large Molecule team was essential to reduce both risk and the time needed for delivery of clinical supplies.

• Translating Biopharma Knowledge To Cell And Gene Therapies

  Streamlining, connecting, and automating workflows to shape the future of cellular treatment delivery has the potential to transform how we treat and potentially cure once life-threatening diseases.

• Can You Trust A Machine For Downstream Bioprocess Buffer Preparation?

  Is automated buffer preparation a solution to the dilemma of balancing increased production capacity against limited footprint expansion alternatives?

• Recommended Mixing Equipment For Tablet Coatings

  Designed for high-speed powder dispersion, the Ross Solids/Liquid Injection Manifold Mixer is well proven in the preparation of tablet coatings. 

• S.U.B. Enhancements For High-Density Perfusion Cultures

  This study presents how strategic enhancements to the sparge and agitation systems of Thermo Scientific HyPerforma S.U.B.s have revealed the potential for a three- to four-fold improvement in mixing and mass transfer performance compared to legacy S.U.B. designs.

• Determination Of Adenovirus Concentration Using Surface Plasmon Resonance

  The performance of two assays for determination of adenovirus concentration based on surface plasmon resonance (SPR) is demonstrated in this application note.