INSIGHTS ON PHARMACEUTICAL LOGISTICS

• 2020 Cold Chain Forecast — Ushering In The Next Decade of Change

  As we cross the threshold into a new decade in 2020, it’s a time to take stock of the significant changes that transformed the pharmaceutical cold chain industry during the past decade. 

• The Power of Digital Transformation

  The pharmaceutical contract services supply chain is not traditionally a sector where technology is a first mover. Approximately 18 months ago, however, PCI Pharma Services determined that there were sufficient proof points in the industry indicating that it should incorporate digital transformation as core to its business strategy. While the company continues on this journey, PCI Pharma Services is already realizing both measurable and intangible benefits.

• Achieving Cell And Gene Manufacturing Scalability: A Conversation With AVROBIO’s Geoff MacKay

  Geoff MacKay, president and CEO of AVROBIO, talks with The Business of Biotech podcast about the scale up obstacles facing the cell and gene therapy space and how AVRO is working to tackle them.

• How Customer Forecasts Support The Integrity Of The Biopharma Supply Chain

  Receiving customer forecasts as early and as completely as possible is critical to the success of the supply chain continuum.

• Bulletproof Your Supply Chain: Hope For The Best, Prepare For The Worst

  8/3/2021

  Explore how to incorporate flexibility in planning to overcome potential challenges, the value of having a contingency plan, and how to use a risk-based approach to determine where a contingency plan is needed.

• New, LN₂-Free Solution For Cryogenic Transport Of ATMPs

  5/14/2021

  Administration of cell therapies, in clinical trials or as commercial products, involves complex logistics between sometimes numerous partners and sites, making timing critical. A better understanding of the boundaries not to be crossed, in terms of transit time and temperature, to maintain cell integrity post-thaw, is studied here.

• Cold Chain Logistics For Cell Therapy Production – A Conversation With Celyad’s Thomas Lequertier

  8/23/2021

  Because cell therapies must be stored and shipped at very low temperatures, maintaining a therapeutic’s integrity through cryopreservation has far-reaching implications for both its efficacy and long-term commercial success. Thomas Lequertier, head of the Cell Therapy Manufacturing Unit at Celyad Oncology, recently sat down with the Business of Biotech podcast to discuss how his company has approached cold chain technology for its CAR-T therapies.

• Qualification Summary: Shippers For Celsius® FFT | FFTp 12L With Safecore™ Technology

  6/11/2021

  Since it is not possible to anticipate every possible transport route, a set of industry-recognized tests was selected to represent a challenging use scenario. The two main risks to frozen material during transport are mechanical and thermal. In this note we have evaluated the  Celsius® FFT | FFTp Box Shipper and Celsius® FFT | FFTp Bulk Shipper using the ASTM D-4169 test for mechanical risks and the ISTA 7D test for thermal risks.

• Shipping Temperatures For Cell Therapies

  5/14/2021

  Cryopreserved cells are often stored at a central facility before being shipped to the clinical location. This study explores the required shipping and storage temperatures for cryogenic cold chain delivery of biological samples.