INSIGHTS ON DRUG DEVELOPMENT

• Amorphous Solids: Implications For Solubility And Stability

  Amorphous solids can enhance drug solubility and bioavailability but introduce stability risks, making careful characterization and control essential for successful pharmaceutical development and manufacturing.

• Automated Bioburden Testing Solution

  Automation is transforming microbial quality control labs, boosting productivity, minimizing errors, and ensuring data integrity. Discover how digitalization is driving Pharma 4.0 and reshaping lab workflows.

• Recombinant Protein Process Development And Scale-Up

  Discover a resin for recombinant protein purification with a standardized protocol that streamlines workflows from lab to production, which saves time and enhances efficiency across development stages.

• Why CMC Continuity Is The Missing Link Between Development And Manufacturing

  Discover why CMC continuity is the missing link between development and manufacturing, and how preserving connected product and process knowledge helps reduce handoff risk, accelerate tech transfer, and strengthen manufacturing readiness.

• Predicting Performance Of Lotions Through Rheological Characterization

  5/6/2026

  Rheological testing shows how small formulation differences influence spreading, flow, and feel during use. With minimal sample volumes, these methods connect lab measurements to real‑world performance.

• Silyl Ether Linkers For Hydroxyl-Bearing Payload Conjugates

  6/19/2026

  Discover an innovative approach to drug conjugation that expands the range of molecules suitable for targeted therapies while preserving their biological activity and enabling controlled drug release.

• An Integrated Analytical Approach To Lipase Risk Management In Biologics Development

  9/8/2026

  Conventional HCP testing cannot confirm whether residual lipases remain enzymatically active. Here, the authors examine why functional activity data are essential for managing polysorbate-related stability risk in biologics development.

• Scale-Up Of An Adherent rAAV Production Process

  11/3/2025

  Fixed-bed bioreactors simplify the scale-up of viral vector production. Discover a system that bridges development and manufacturing with data confirming consistent performance across scales.

• Molecular Properties Of PROTACs And The Relationship To Formulation Design

  3/4/2025

  Here, we conduct a comprehensive analysis of diverse PROTAC (Proteolysis Targeting Chimeras) structures, evaluating their calculated physicochemical properties to identify key trends.