INSIGHTS ON DRUG DEVELOPMENT
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Overcoming Challenges To High-Concentration Formulation Development
Explore how the S-HiCon™ platform optimizes high-concentration therapeutic antibody formulations, overcoming stability and manufacturability challenges to deliver safe, effective therapies.
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Ultra-Low Cross-Linked Microgel Purification
ULC microgel purification is often slowed by linear polymer contamination and limitations of centrifugation. Explore how hollow fiber TFF improves filtration efficiency and supports scalable processing.
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Redefining OSD Development Through Foresight And Innovation
From early formulation challenges to scale-up and commercial readiness, proactive planning and integrated capabilities help teams anticipate risks, accelerate decision-making, and maintain momentum across development.
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3D Cell Culture Reveals Undetectable Drug Efficacy In Traditional Systems
Drug discovery now targets cancer stem cells (CSCs) to achieve long-term tumor eradication, which moves beyond traditional chemotherapeutics. Discover an advanced screening platform that better predicts CSC inhibitor efficacy.
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Expanding Translational Research Concepts With Genedata Profiler11/26/2024
The biopharma industry leverages Genedata Profiler to integrate, curate, and analyze diverse R&D data, enabling collaborative, compliant, and AI-driven translational research to optimize drug development.
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Optimization And Scale-Up Of A Plasmid DNA Production Process9/30/2025
Optimizing pDNA production in E. coli requires strategic media selection and scale-up planning. Explore a study that identifies ideal conditions for high-yield manufacturing.
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Lentiviral Vector Upstream Process12/12/2025
Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.
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The 5 Ws Of A Human Factors Strategy3/31/2025
A human factors strategy ensures medical products are safe, effective, and compliant by integrating user-focused design early, reducing risks, and optimizing regulatory approval processes.
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Building A Human-Centric Future For Biologics Development6/25/2026
Biologics are advancing rapidly, but complexity challenges traditional models. Gain insight into how human-relevant approaches like NAMs and microphysiological systems are gaining traction.
DRUG DEVELOPMENT SOLUTIONS
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Decode 3D biology in real time*
The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research. Thanks to THUNDER Live, your images reveal the finest structural details already in the live image. No hassle with out-of-focus blur while maintaining the capabilities and ease-of-use typical for Leica stereo microscopes.
A THUNDER Imager Model Organism is the optimal instrument for studying, e.g., Drosophila, C. elegans, zebrafish, plants, and mice. One device for screening, positioning, and imaging your specimen. Simplify your workflow and study model organisms from a large overview to the highest detail.
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STELLARIS DLS Digital Light Sheet Microscope
Light Sheet Re-Imagined
STELLARIS 5 and STELLARIS 8 Digital LightSheet (DLS) unite in one place a confocal system and a light sheet microscope – a unique combination aimed to make your research more versatile. The exclusive vertical design of DLS, enabled by Leica Microsystems’ proprietary TwinFlect mirrors, allows you to combine confocal and light sheet imaging in the same system, so you can easily adapt the microscopy method to your experimental needs.
DLS also brings flexibility to your research with the capacity to image different types of samples, such as model organisms, organoids or cleared tissue, and the ability to take advantage of the full excitation spectrum. This flexibility is possible thanks to the STELLARIS White Light Laser and the ability to perform multi-position light sheet experiments whilst using standard glass bottom plates. All of this helps you add new and better ways to explore your research questions.
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Waters series of chromatography columns and standards offer scientists the diverse range of chromatographic selectivities needed to help characterize today's biotherapeutics and biosimilars.
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Characterize Samples and Identify Unknown Components
Do you often need to identify unknown compounds from complex samples? ACD/MS Structure ID Suite offers a simple, replicable workflow for generating and narrowing down structural candidates.
- Deconvolute complex LC/MS and GC/MS data into individual component traces
- Search proprietary and commercial databases for spectral matches
- Search PubChem for accurate-mass and molecular-formula matches
- Narrow down candidate structures by retention time and fragment include/exclude lists
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Understand and predict human response earlier in the drug development process, and harness the advantages of Organ-on-a-Chip technology without needing to invest in capital equipment or train personnel.