INSIGHTS ON DRUG DEVELOPMENT
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Formulation Development Of Enterically Protected Spray Dried Dispersions
Adrulipase spray-dried dispersions were evaluated to create an orally delivered, enteric-protected enzyme. The lead formulation provided the best acid protection, rapid release, and stability.
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Impurity Monitoring Of GLP-1 Therapeutic Peptide Retatrutide
TFA resolves impurities that formic acid leaves co-eluting, but it suppresses MS signal. Multiple heart-cutting 2D-LC reconciles the two for a triple-agonist GLP-1 peptide with closely related variants.
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Assessing Particle Generation In A Single-Use Mixing System
Explore how particle levels remained stable during 24 hours of high-speed mixing, even under extreme temperatures, confirming a system’s suitability for final fill and other particulate-sensitive applications.
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Take The Wheel And Drive Your Oligo Synthesis Where You Want
Explore the evolving oligo therapeutic landscape while identifying common challenges of bringing production in‑house and the key factors that shape long‑term success for smoother scale‑up.
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Engineering Affordability Into Customizable Microscopy Platforms10/27/2026
Microscopy systems configured around a specific imaging application can offer researchers more control than off-the-shelf instruments, with OEM components, software reprogramming, and more.
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Expanding Opportunities For Inhaled Drug Delivery7/11/2025
Review the challenges and intricacies of effectively delivering drugs to the lung and the advantages of using nanoparticles and gentle particle processing techniques to enable delivery of sensitive drugs.
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EMA Support For Rare Disease Therapies6/10/2025
Review how the EMA supports rare disease drug development through regulatory and financial incentives for therapies that meet strict eligibility and ongoing compliance criteria.
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ADC Development Grows More Complex — SPR Insights Bring Clarity4/14/2026
Explore how real-time kinetic analysis reveals how conjugation, linker chemistry, and drug loading influence antibody–antigen interactions, while enabling sensitive detection of anti-drug antibodies.
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Scale-Up Of AAV Production In Fixed-Bed Bioreactors3/31/2026
Consistent AAV production is critical for manufacturing. See how aligned strategies deliver comparable cell growth, metabolic trends, and rAAV5 titers from development through production.
DRUG DEVELOPMENT SOLUTIONS
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Understand and predict human response earlier in the drug development process, and harness the advantages of Organ-on-a-Chip technology without needing to invest in capital equipment or train personnel.
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In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.
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We simplify pre-production workflows—for both upstream and downstream—by delivering fit-for-purpose process liquid and buffer preparation solutions that enable you to produce life-changing therapeutics and vaccines, faster.
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Routine cell culture? Check!
For researchers who need consistent experimental outcomes, Mateo TL enables all lab members to check and document cell growth status conveniently and comfortably.
Measure confluency consistently, thereby increasing the confidence in the success of their downstream experiments.
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For workflows where trace contamination can derail sensitivity, consistency matters. See how rigorously tested reagents and isolation chemistries support cleaner controls and more confident results.