INSIGHTS ON DRUG DEVELOPMENT

• Technology Selection To Enhance Bioavailability

  Bioavailability challenges are among the toughest problems faced by today’s formulators. Most of the prospective drugs in pharmaceutical pipelines today have low solubility, which means the active therapeutic ingredients can’t be absorbed when patients take them orally. This paper gives an overview of obstacles to bioavailability and summarizes the Lonza technology selection process.

• How Can We Predict Immunogenicity Earlier?

  With many biotherapeutics a strong immunogenic response can limit the effectiveness of the treatment or cause a more serious illness. This remains a challenge for scientists as the underlying mechanisms of unwanted immunogenicity still aren’t completely understood. Detecting and preventing unwanted sources of immunogenicity as early in the discovery process as possible has become a top priority for research organizations since biotherapeutic development becomes increasingly costly as it moves downstream.

• Platform Cell And Gene Therapy Media Development

  This article highlights a case study on the removal of serum from the expansion step of an autologous cell therapy in a cost-effective manner without affecting cell performance.

• Zydis® ODT Provides Better Treatments

  Discover how Catalent's oral drug delivery offerings can help get your molecule to market faster. In this case study, learn the many benefits of our product offerings.

• Preventing Dementia Through A Virtual Twin Brain

  10/5/2020

  Virtual human twins have begun to transform the development of new therapies as well as the patient experience, closing the loop between the manufacturer and the patient. In this webinar, we will discuss the current state of The Living Brain Project and how it is being applied to traumatic brain injury, neuromodulation, neurodegenerative disease progression, and drug delivery through cerebrospinal fluid.

• Data Science Makes For Better Lab Science

  5/12/2021

  Watch this webinar to discover how technology for searching, machine learning, predictive and prescriptive analytics, and modeling and simulation can help lab operations to leverage scientific data end-to-end to make knowledge-driven decisions in real time to ultimately speed time to market. Key topics covered: How to unlock the potential of your existing lab data; How predictive and prescriptive analytics can help scientists become more efficient and effective; Uncover new opportunities for modeling and simulation to save time during both short and long projects.

• Single-Use Platforms Accelerate Viral Vaccine Development, Manufacturing

  10/31/2019

  Analysts predict the vaccine market could grow at as much as 10.3 percent through 2024 (CAGR). Single-use platforms might be pivotal to meeting that demand.

• Scale-Up: The Next Mountain To Climb In Technology Transfers

  5/4/2021

  Turning a promising drug candidate into a successful pharmaceutical product involves scaling-up the processes so a commercial supply can be achieved, which involves technical hurdles.

• Improve Biopharma Fermentation With Innovation, Collaboration

  12/28/2020

  Organizations developing products requiring fermentation often create custom processes from scratch, leaving room for inefficiencies, lost value, and, in the case of significant error, costly time delays.