INSIGHTS ON DRUG DEVELOPMENT

• Solving Bioavailability Challenges In bRo5 Drugs

  Leverage mechanistic, material-sparing formulation strategies to enhance bioavailability and accelerate development of challenging bRo5 small molecules, even with limited resources.

• Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development

  Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.

• Comprehensive Workflow For The Quantification Of Peptides And Proteins

  Biologics are transforming medicine, with semaglutide leading the way. Discover how an automated LC-MS/MS workflow enables high-sensitivity quantification of peptides in plasma.

• Rational Design And Material-sparing Strategies For Enabled Intermediates And Drug Products

  A material-sparing strategy integrating formulation mapping, lab-scale spray drying, and compact screening can accelerate risk identification and inform first-round tablet formulation decisions for poorly soluble APIs.

• Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies

  7/15/2026

  In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.

• Ask Us Anything: Matt Bio On Peptide Commercialization Trends

  7/23/2026

  Matt Bio, CSO of Cambrex and President of Snapdragon Chemistry, on the capacity bottleneck behind peptide shortages — and why moving from solid-phase to liquid-phase synthesis unlocks reactors already sitting idle around the world.

• Everyday Medicines, Complex Manufacturing: 5 Reasons They Aren't Simple To Make

  10/15/2026

  Tablets and liquid medicines look simple to the patient, but their reliability depends on formulation choices made early and on technical expertise that continues well after commercial production begins.

• A Simple Method For Cell Growth Media Preparation

  11/3/2025

  Explore how powder media and sterile fluid handling can reduce contamination risk and improve efficiency in viral vector production, especially for HEK293-based AAV workflows.

• Streamlining pDNA: Capacity, Complexity, And Cutting-Edge Solutions

  11/20/2025

  Learn how flexible facility design and process innovation are accelerating pDNA manufacturing, as well as key strategies to avoid scale-up pitfalls and meet growing therapeutic demand.