INSIGHTS ON DRUG DEVELOPMENT

DRUG DEVELOPMENT SOLUTIONS

  • Calculators & Predictors for LogP, LogD, pKa, Aqueous Solubility, and more…

    The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

    ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

    • Predict aqueous solubility,* boiling point, logD,* logP,* pKa,* Sigma, and other molecular descriptors for organic compounds, from structure
    • Evaluate the calculated results with sorting, plotting tools
    • Assess the reliability of predicted physicochemical property values
    • Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
    • Train predictors with experimental data to better reflect novel chemical space
    • Include custom models and in-house prediction algorithms

    *Models are trainable with experimental data

  • Examine how sterilizing-grade filters with high flux and broad compatibility support efficient bioprocessing across mAbs, vaccines, and viral vectors.

  • A smarter approach to method selection helps labs reduce guesswork and maintain consistent results. Learn how structured workflows and guided optimization can support confident decisions.

  • Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.

    With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.

  • Understand Your Biotransformation Data

    MetaSense helps you make sense of all your metabolite identification (MetID) data. Move beyond complex workflows that have you flipping back and forth between a dozen programs.

    With a single interface for prediction, data analysis, and knowledge dashboards, make data-driven decisions swiftly.

    • Collect all your MetID data and view it in one place
    • Auto-generate biotransformation maps and kinetic plots
    • Click between interactively linked maps and plots to see your data at any depth
    • Reprocess data directly from MetaSense
    • Draw conclusions about a drug candidate’s metabolism and viability