INSIGHTS ON DRUG DEVELOPMENT

• Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins

  Protein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.

• Optimize Process Performance And Maximize HCP Removal

  Compare filtration strategies and explore how filter selection affects host cell protein removal, processing efficiency, and the balance between impurity clearance and filtration performance.

• How Solid-State Characterization Shapes Drug Development

  Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.

• Streamlining Drug Development: From Developability Assessment To High-Concentration Formulation Development

  Explore a strategic approach to accelerating biologics formulation by gaining early insight into molecular properties and optimizing high-concentration conditions with minimal protein input.

• Deciphering Nanoparticle Properties With AF4

  5/6/2026

  Discover how risk‑based, phase‑appropriate synthesis enables safe, efficient production of highly potent compounds while balancing speed, worker safety, and regulatory readiness in early development.

• Patented Process For Intermediates Useful For Deucravacitinib

  3/13/2026

  Discover how this patented synthetic approach to Deucravacitinib intermediates can improve yield, simplify purification, and support scalable, regulatory-aligned manufacturing.

• Scaling Up Your E. Coli pDNA Process From Parameter Screening To Pilot Scale

  6/26/2025

  Discover a systematic approach to scalable plasmid DNA production using E. coli OneShot Top10, which features DOE-driven optimization and key insights for efficient biomanufacturing success.

• Ophthalmic Drug Delivery: Meeting Modern Challenges With A Next Generation Solution

  8/17/2026

  Ophthalmic injectable packaging demands early strategic attention. Learn how silicone oil contamination, particulate limits, and dosing accuracy challenges can derail development programs and what it takes to stay compliant.

• Column Selection For RPLC-UV Impurity Analysis

  7/17/2025

  Explore the performance of four column chemistries for RPLC-UV impurity analysis of liraglutide and semaglutide, which offers practical guidance for method development in peptide-based therapeutics.