INSIGHTS ON DRUG DEVELOPMENT
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![Scientist Thinking GettyImages-1370154329]( "Scaling Up Your Methods With USP <621> - Part 2: Hardware")
Scaling Up Your Methods With USP <621> - Part 2: HardwareLearn about the hardware changes that allow for scaling and modernization of chromatographic methods and how mismatching particle size and liquid chromatographic systems can result in poor performance.
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![Sartorius BLog]( "With Newer Cell Lines Available. Why Continue To Use The CHO DG44 Variant?")
With Newer Cell Lines Available. Why Continue To Use The CHO DG44 Variant?A variety of CHO cell lines are used as hosts in the production of biologics. We discuss why we use the CHO DG44 variant for our CHO cell line development platform.
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![Scientist laboratory ipad GettyImages-500323894]( "How Dwell Volume And Extra-Column Volume Impact Method Transfer")
How Dwell Volume And Extra-Column Volume Impact Method TransferUnderstand how system factors like dwell volume and extra-column volume contribute to method performance across labs and how this knowledge can increase the success of method transfer.
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![GettyImages-1303133599-lab-computer-research-virus]( "Microcarrier-Based Production Of Dengue Virus In An Optimized Animal-Free Virus Production Medium")
Microcarrier-Based Production Of Dengue Virus In An Optimized Animal-Free Virus Production MediumThe use of undefined components in animal product-free (APF) cell culture media is one source of variability in cell culture processes. Explore how microcarriers provide an economical and robust platform for vaccine production using adherent cell types.
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Streamline Method Validation In Pharmaceutical Product Development9/21/2022
Method validation is a time-consuming activity prone to human error. Find out how a method validation manager can provide a single, comprehensive solution for your validation activities.
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Ensure High Quantity And Quality Of Isolated Bacterial Ribonucleic Acid (RNA)4/29/2022
In this scientific brief we evaluate the performance of the the Pall Nucleic acid binding (NAB) Nanosep centrifugal device for nucleic acid isolation.
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Embracing LC-MS Analytical Techniques Into Regulated Laboratories5/4/2022
We address the additional compliance challenge in biopharma of the requirement of complex analytical instruments that are not traditionally used in highly regulated labs.
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Scaling Up Your Methods with USP <621> - Part 3: Software10/31/2022
Learn about modifications to certain calculations and how they will be addressed using our software along with how relevant naming conventions and calculations will be maintained to help customers.
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Tips To Improve Size-Exclusion Chromatography For mAbs And ADCs5/2/2022
In this article, we will explore tips to improve the method of size-exclusion chromatography (SEC), which is often used to measure monomer/aggregate and fragment content of mAbs and ADCs.
DRUG DEVELOPMENT SOLUTIONS
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![GettyImages-1127105013-lab-computer-research-scientist]( "Solid Form Services")
We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.
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![BD-vystra]( "BD Vystra Disposable Pen For The Self-Injection Of Chronic Disease Medications")
This device is designed for use with a wide range of drug therapies that require variable dosing.
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![OptimalDose]( "Better Treatments By Design: Optimal Dose Development And Manufacturing")
We understand stakeholder needs and match them to the widest array of drug delivery solutions to give your therapy the best potential for success on the path from Phase II through scale-up and commercial supply.
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![Low Temperature Benchtop Bath: Charpycool]( "Low Temperature Benchtop Bath: CharpyCool")
The new CharpyCool is a mechanically refrigerated bench top bath that eliminates the need for costly consumables such as liquid nitrogen or dry ice. Compact and completely self-contained, the CharpyCool offers up to 8 liters of working fluid volume enabling up to 91 Charpy impact test specimens to be accommodated at temperatures between -80°C and +30°C. A powerful variable speed magnetic stirrer and vortex breaker provide excellent temperature uniformity and stability enabling superior results. PID control enables the CharpyCool to sustain precise temperature control to within ± 0.1°C. The CharpyCool includes a digital temperature display, and an optional Charpy Rack is available which allows multiple-specimen loading and easy access to monitor your testing.
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![Antibody antibodies GettyImages-1356994686]( "Antibody Therapeutics Purification")
We have developed an innovative portfolio of affinity chromatography resins to help you solve challenges in the downstream process of next-generation antibody therapeutics. These resins are specifically designed for the purification of engineered monoclonal antibody (mAbs) modalities.
