INSIGHTS ON DRUG DEVELOPMENT
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Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins
Protein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
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Optimize Process Performance And Maximize HCP Removal
Compare filtration strategies and explore how filter selection affects host cell protein removal, processing efficiency, and the balance between impurity clearance and filtration performance.
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How Solid-State Characterization Shapes Drug Development
Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.
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Streamlining Drug Development: From Developability Assessment To High-Concentration Formulation Development
Explore a strategic approach to accelerating biologics formulation by gaining early insight into molecular properties and optimizing high-concentration conditions with minimal protein input.
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Deciphering Nanoparticle Properties With AF45/6/2026
Discover how risk‑based, phase‑appropriate synthesis enables safe, efficient production of highly potent compounds while balancing speed, worker safety, and regulatory readiness in early development.
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Patented Process For Intermediates Useful For Deucravacitinib3/13/2026
Discover how this patented synthetic approach to Deucravacitinib intermediates can improve yield, simplify purification, and support scalable, regulatory-aligned manufacturing.
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Scaling Up Your E. Coli pDNA Process From Parameter Screening To Pilot Scale6/26/2025
Discover a systematic approach to scalable plasmid DNA production using E. coli OneShot Top10, which features DOE-driven optimization and key insights for efficient biomanufacturing success.
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Ophthalmic Drug Delivery: Meeting Modern Challenges With A Next Generation Solution8/17/2026
Ophthalmic injectable packaging demands early strategic attention. Learn how silicone oil contamination, particulate limits, and dosing accuracy challenges can derail development programs and what it takes to stay compliant.
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Column Selection For RPLC-UV Impurity Analysis7/17/2025
Explore the performance of four column chemistries for RPLC-UV impurity analysis of liraglutide and semaglutide, which offers practical guidance for method development in peptide-based therapeutics.
DRUG DEVELOPMENT SOLUTIONS
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We deliver custom assay development, screening, potency, and selectivity testing services for the pharmaceutical, biopharmaceutical, and agrochemical industries.
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Gain insight into how faster structural elucidation is possible with integrated mass spectrometry workflows that combine intelligent data analysis, spectral matching, and automation.
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Understand Your Biotransformation Data
MetaSense helps you make sense of all your metabolite identification (MetID) data. Move beyond complex workflows that have you flipping back and forth between a dozen programs.
With a single interface for prediction, data analysis, and knowledge dashboards, make data-driven decisions swiftly.
- Collect all your MetID data and view it in one place
- Auto-generate biotransformation maps and kinetic plots
- Click between interactively linked maps and plots to see your data at any depth
- Reprocess data directly from MetaSense
- Draw conclusions about a drug candidate’s metabolism and viability
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The BioAccord™ LC-MS System with dedicated workflows for the Sartorius Ambr® 15 and small bioreactors enables process engineers to directly measure Product Quality Attributes (PQAs) and cell culture media.
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Platform of automated, single-use systems for tangential flow filtration at multiple scales.