INSIGHTS ON DRUG DEVELOPMENT

• Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up

  SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.

• Solving Bioavailability Challenges In bRo5 Drugs

  Leverage mechanistic, material-sparing formulation strategies to enhance bioavailability and accelerate development of challenging bRo5 small molecules, even with limited resources.

• Navigating Nitrosamine Impurities In Pharmaceutical Drug Development

  Understanding formation mechanisms and potency categorization allows developers to mitigate risks early, ensuring regulatory compliance and patient safety without compromising product performance.

• Cell Retention Technology And Specialized Cell Culture Media

  Explore how perfusion technology is transforming upstream bioprocessing by boosting productivity, reducing costs, and enabling process intensification while overcoming cell retention challenges.

• Calcium Carbonate As TiO2 Alternative In Coating

  11/7/2025

  Explore how calcium carbonate can replace titanium dioxide in tablet coating, as well as learn formulation strategies and review color performance data to support high-quality finishes in applications.

• Building A Human-Centric Future For Biologics Development

  6/25/2026

  Biologics are advancing rapidly, but complexity challenges traditional models. Gain insight into how human-relevant approaches like NAMs and microphysiological systems are gaining traction.

• NanoImprove The Performance Of Your Formulations

  9/24/2024

  Learn how Nanoforming can help improve the performance of your molecule by increasing drug loads, improving bioavailability, enhancing drug delivery profiles, and supporting product differentiation.

• Pioneers And Visionaries Of Nucleic Acid And Nanoparticle-Based Therapeutics

  12/12/2024

  Explore the future of nucleic acid and nanoparticle-based therapeutics, including mRNA, CRISPR, and gene editing, as experts discuss innovative solutions for complex health challenges.

• Patented Process For Intermediates Useful For Etrasimod Arginine

  3/13/2026

  Explore how rethinking the synthetic strategy for Etrasimod can overcome the limitations of legacy routes, enabling more efficient chirality control, improved scalability, and more practical industrial API production.