Insights On Pharmaceutical Production

1. Tips For Successfully Scaling Your cGMP Manufacturing 6/23/2022

   What are the specific obstacles to expanding manufacturing capacity? Cell therapy industry leaders share what to look for in a solutions provider and recommendations for navigating your road ahead.

2. A New Way Of Looking At De-Nesting And Re-Nesting Solutions 2/3/2021

   Systems that process drug containers must prioritize container integrity and gentle handling to prevent breakages and product losses. We have developed the innovative, automatic handling unit Nestor to process ready-to-use containers, such as syringes, to and from nests and tubs.

3. The Role Of Micronization With Dry Powder Inhaler Technologies 12/6/2021

   Read about a new generation of spiral jet mills meeting specific particle size distribution (PSD) targets that has been developed.

4. Introducing The Enhanced And HyPerforma™ DynaDrive™ Single-Use Bioreactors (S.U.B.s): Meeting The Demands Of Intensifying Upstream In Single-Use 10/15/2020

   S.U.B.s have emerged as a tool-of-choice in many PD and Pilot spaces and are now transitioning into certain commercial manufacturing spaces. Here we describe simple yet effective enhancements that enable Thermo Scientific HyPerforma S.U.B.s to meet the mass-transfer and mixing needs of intensifying processes at 50-500 L scale, while leveraging the hardware of existing systems. We also introduce a next generation of single-use bioreactor – DynaDrive S.U.B.

5. Selecting Sterile API Transfer Technologies 12/17/2021

   A CDMO was looking to solve the issue of charging sterile drug substance into a mixing tank which is a widespread problem in aseptic processing and particularly in formulation. 

6. High Potency Drug Manufacturing: Molecule To Market 8/5/2020

   The pharmaceutical landscape continues to evolve, with much R&D focusing on more specialized medicines. As the biological activity and specificity of the API increases, dosage strengths decrease – resulting in increased potency of the APIs in terms of occupational handling for drug product manufacture. This paper examines the process of successful high potency drug manufacturing and delivery to market.

7. HFC Single-Use Sterile Disconnections 12/9/2020

   With a simple push of the thumb latch, sterility is maintained on both sides of the system during the disconnection process. Product Manager Maria Bollensen shows how easy it is.

8. Standardize For Success In Single-Use Technology 10/30/2020

   Eliminating the long, resource-intensive decontamination and sterilization steps associated with multi-use equipment, single use proves it can help biopharma organizations boost operational efficiency.

9. Spray Drying: Advantages And Disadvantages 2/28/2022

   When it comes to formulation development, pharmaceutical spray drying is one of the most versatile solutions. Review a detailed look at the steps involved in spray drying and the benefits and downsides.

10. Accelerated Probe And Primer Production To Enable COVID-19 Testing With The SP Genevac HT Series 3i Evaporator 8/25/2020

    As the novel coronavirus (COVID-19) pandemic is progressing throughout 2020, it has become evident that millions of testing kits are needed internationally every single day. This article explores how a leading provider of tools and technologies for genetic analysis, LGC, Biosearch Technologies, is aiding in the fulfilment of this demand, assisted by evaporation technology from SP Genevac.