Insights On Pharmaceutical Production

1. Technical Considerations For Developing Oral Solids (Part 1) 8/3/2020

   Navigating your oral solids project from development through commercial manufacture can be a challenging path. In a two-part series, four oral solids experts from Pfizer CentreOne’s global network and partner organizations discuss the technical considerations to be aware of. In this first installment, we look at the importance of technical groundwork and understanding excipients in the early stages of your project.

2. Critical Considerations About The Future Of Global Cell Culture Bioprocessing 4/2/2019

   In today’s changing industry, it is critical we consider several factors about cell culture bioprocessing and the impact they will have on the future of patient treatment.

3. Advantage Of Antibody Based Selectivity In The Purification Of Biologics 2/11/2020

   By taking advantage of antibody based selectivity, Camelid heavy-chain antibody fragments have proven to be a reliable immuno-affinity chromatography solution in the downstream process of biologics.

4. Avoiding HPAPI Contamination 3/20/2019

   Strict regulations regarding the manufacture of HPAPIs require that pharmaceutical companies and CMOs carefully select equipment, outline processes and deploy appropriate containment strategies. 

5. Efficient Cleaning-In-Place Methods For Protein-Based Antibody Affinity Chromatography Resins 10/2/2018

   This whitepaper discusses cleaning of affinity resins intended for use in the purification of monoclonal antibodies and antibody fragments.

6. Efficient mAb Aggregate Removal By Hydrophobic Interaction Chromatography 2/11/2020

   This poster shows the optimization of POROS™ HIC resin-use in high-throughput screening (HTS) and subsequently upscaling in both Bind-Elute (B/E) and Flow-Through (FT) mode.

7. Dec Group Contained Powder Handling Systems 9/2/2020

   Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.- Dec Group is your partner in powder handling and process contamination technologies. With locations around the globe we have over 30 year of experience in contained and sterile powder handling solutions. This video highlights our capabilities and our state-of-the-art solutions for sophisticated risk management.

8. Accelerated Probe And Primer Production To Enable COVID-19 Testing With The SP Genevac HT Series 3i Evaporator 8/25/2020

   As the novel coronavirus (COVID-19) pandemic is progressing throughout 2020, it has become evident that millions of testing kits are needed internationally every single day. This article explores how a leading provider of tools and technologies for genetic analysis, LGC, Biosearch Technologies, is aiding in the fulfilment of this demand, assisted by evaporation technology from SP Genevac.

9. 5 Steps To Accelerated Biologics Manufacturing And Robust Scale-Up 5/24/2019

   A platform approach to process characterization ensures accuracy and results in a consistent product, which facilitates efficient BLA filing and acceleration to commercial scale.

10. How CDMO Flexibility In Upstream Production Improves Speed To Market 9/10/2020

    To provide the best service, a CDMO's facility should be equipped with flexible manufacturing platforms that can be adjusted for multiple customers while also mitigating risk.