Insights On Pharmaceutical Production

  1. Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers 10/7/2025

    Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.

  2. From Molecule To Milestone: Fast Track Formulation 2/26/2026

    Fast‑track, data‑driven formulation strategies align early decisions with long‑term goals, enabling First‑in‑Human progress while reducing risk, avoiding rework, and supporting manufacturable development.

  3. Remote Measurements For Bulk Samples 12/29/2025

    Remote Raman spectroscopy enables accurate material identification at long distances without complex focusing. Learn how pathlength, sample properties, and substrate choice impact signal quality.

  4. Release, Redefined: QC Testing Across In Vivo And Ex Vivo CAR-T 7/13/2026

    As CAR-T manufacturing evolves, QC strategies must adapt. Learn how identity, potency, sterility, and safety testing support faster release decisions and broader patient access.

  5. What is Hot Melt Extrusion, And How Can It Benefit Your Drug Product? 6/17/2026

    Poor API solubility delays pipelines. Discover how hot-melt extrusion creates amorphous solid dispersions to break down crystal lattices and boost bioavailability via solvent-free manufacturing.

  6. A Comprehensive Solution With Targeted And Non-Targeted Approaches 8/26/2026

    Explore how non-targeted NGS and targeted molecular assays can work together during cell line characterization to provide broad virus detection while supporting evolving regulatory expectations.

  7. Streamline Your mAb Manufacturing With Strategic Development And CDMO Compatibility 6/4/2025

    Though the journey to mAb development begins at lab scale, for clinical trials and commercial distribution, a production process must be streamlined and scalable to 2,000 L production and above.

  8. HPLC Method Development For Monoclonal Antibody Aggregates With SEC 7/13/2026

    SEC for monoclonal antibodies is not always as simple as choosing a column and running PBS. Secondary interactions can affect recovery, making thoughtful method development essential.

  9. The Status Quo Of Oligonucleotides Is Not The Future 12/2/2024

    The oligonucleotide field is booming, but manufacturing challenges loom. Experts discuss optimizing production for these promising therapies with flexible, sustainable, and high-yield approaches.

  10. Mild pH Protein A Purification Step With A Mild Elution Resin 5/22/2026

    As antibody formats diversify, low-pH protein A elution can drive aggregation and yield loss. Learn how milder elution conditions during capture can help protect sensitive molecules and ease challenges.