Insights On Pharmaceutical Production

  1. Scaling And Migration Of A HILIC Method For Related Compounds Of Ribavirin 9/17/2024

    This study demonstrates the successful scaling and migration of a hydrophilic interaction liquid chromatography method for ribavirin analysis from a sub-2 µm column to larger particle sizes on different HPLC systems.

  2. Why Is The Bioreactor Square? The Geometry Behind Exceptional Mixing 3/30/2026

    Cuboid bioreactor design eliminates vortexing through natural baffling, delivering homogeneous mixing and consistent nutrient distribution for high cell density upstream processes.

  3. Impact Of Peptone Supplementation With CHO Cell Lines In Chemically Defined Media 10/30/2024

    Explore the impact of peptone supplementation on CHO cell lines in chemically defined media, focusing on its effects on growth, productivity, and protein quality across various peptone blends.

  4. mRNA Manufacturing With Fed-Batch In Vitro Transcription 2/13/2026

    A milliliter-scale approach to IVT optimization reveals how controlled feeding, precise pH management, and real-time monitoring can boost mRNA yield and streamline scale-up to larger bioreactor volumes.

  5. How Modular Workflows Are Redefining CAR T Manufacturing 7/30/2026

    Learn how flexible modular workflows can help manufacturers improve process adaptability, throughput, and control while preserving key CAR T quality attributes, including transduction efficiency.

  6. Working With Clients To Develop Manufacturing Processes 7/23/2026

    Greg Buenger, Group Leader of Chemical Development at Cambrex Charles City, on what it actually looks like when R&D hands a process to the plant — chemists on the floor for the first batch, advising operators and troubleshooting in real time.

  7. Mild pH Protein A Purification Step With A Mild Elution Resin 5/22/2026

    As antibody formats diversify, low-pH protein A elution can drive aggregation and yield loss. Learn how milder elution conditions during capture can help protect sensitive molecules and ease challenges.

  8. Prevent The Risk Of Cross-Contamination With Microbial Colony Pickers 3/17/2025

    Explore a microbial colony picker that streamlines lab workflows to ensure rapid and accurate genetic library screening. Key features include UV sanitization, pin washing, and halogen drying, which meets GMP standards.

  9. Product-Wet Integrity Testing: Risk-Based Strategies 5/22/2026

    When standard water‑based integrity testing falls short, product‑wet approaches can offer a more representative alternative. Learn how risk‑based strategies are used to establish reliable test limits.

  10. Enhancing Biopharmaceutical Production Through Advanced Mixing 6/30/2026

    Eliminate particulate contamination and product degradation in downstream bioprocessing. Learn how frictionless, levitating impeller technology ensures low-shear mixing and high yields.