Insights On Pharmaceutical Production

  1. Sterilizing-Grade Filtration Of mRNA Encapsulated Lipid-Nanoparticles 9/2/2026

    Compare sterilizing-grade membrane performance at high and low pressures, including throughput, bacterial retention, and the effects of filtration on particle diameter and encapsulation efficiency.

  2. Assessing Particle Generation In A Single-Use Mixing System 11/13/2025

    Explore how particle levels remained stable during 24 hours of high-speed mixing, even under extreme temperatures, confirming a system’s suitability for final fill and other particulate-sensitive applications.

  3. Bioprocess Optimization: Leveraging Functional DOE With Time-Based Insights 3/5/2025

    Explore the key differences between traditional DOE and Functional DOE as Seongjin Kim demonstrates how the latter enhances bioprocess optimization through a fed-batch cell culture example.

  4. Lower Punch Tip Bending / Buckling 11/11/2024

    When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

  5. Framework To Deliver Standardized, Reliable Biomanufacturing Facilities 11/25/2025

    Standardized, continuously optimized facility design enables scalable, efficient, and reliable biomanufacturing that improves quality, accelerates timelines, and ensures consistent performance across sites.

  6. Risk-Based Spray Drying Scale-Up: From Early Feasibility To Commercial Control Strategy 8/20/2026

    Discover how science, modeling, risk assessment, and DoE turn spray-dried dispersion scale-up from trial-and-error transfer into a predictable, robust path to commercial manufacturing.

  7. Scalability From 5L To 50L Using The DynaDrive Single-Use Bioreactor 8/14/2025

    Maintaining a consistent bioprocess when scaling from 5 L to 50 L is achievable. This study shows how to successfully scale processes while maintaining cell density, viability, and protein production.

  8. In Vivo Manufacturing: When The Body Becomes The Bioreactor 5/15/2026

    Breakthrough therapies are reshaping medicine, but manufacturing complexity is holding them back. Discover how rethinking production and delivery could expand reach and improve patient experience.

  9. Difco TC Yeastolate Ultra-Filtered (TCY UF) In Scale-Up Optimization 10/30/2024

    Explore how Difco™ TC Yeastolate ultra-filtered (TCY UF) enabled over 100% improvement in titer for CHO cell culture through feed optimization and bioreactor scalability in a real-world application.

  10. Cell Culture Media Demystified For Performance, Quality, And Innovation 11/13/2025

    Cell culture media isn’t one-size-fits-all. Learn how media composition, customization, and analytics can dramatically improve cell growth, productivity, and product quality for complex processes.