Article | April 16, 2025

9 Essential Oligosynthesis Component Needs

By Steve Foy, manager, products and brand strategy at Asahi Kasei Bioprocess America

GettyImages-1173476370 DNA

The synthesis of oligonucleotides (oligos) is foundational to advancements in areas like gene silencing and immunomodulation. As the oligosynthesis market rapidly expands, projected to reach $22.5 billion by 2028, the pressure mounts on production facilities to scale efficiently.

Moving from lab research to commercial manufacturing requires a strategic investment in specialized equipment. It's not just about having an oligosynthesizer; critical auxiliary systems for cleavage, purification, buffer management, and analysis are equally vital for optimizing yield and purity while managing costs. Understanding the function and necessity of each component is the first step toward building a robust production line.

Explore the full breakdown of the 9 essential oligosynthesis components in the complete article.

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