Insights On Solid Dose Manufacturing

1. Mini-Spray Dryer Encloser Solution For Pharmaceutical Application 1/27/2020

   A client required the design and build an enclosure that could house the Buchi B-290 Mini-Spray Dryer during process. See how this designer/manufacturer was able to provide a solution that could offer containment down to less than one microgram per cubic meter.

2. Ensuring Safe Handling Of High Potency Products 9/14/2020

   Due to the high potency of the pharmaceutical active ingredients (APIs), machine operators have to be protected and while at the same time, humans are a high source for product contamination. In pharmaceutical manufacturing facilities, isolators are becoming increasingly important as they can achieve the desired level of protection and security. This article presents a fully integrated highly complex isolator and process equipment solution offering high safety, efficient control and cleaning features as well as full compliance in terms of manufacturing regulations.

3. Containment Liability: Choosing Assurance Or Insurance 6/4/2020

   Engineering controls designed to mitigate exposure and create separation between the operator and toxic material are available in many forms, all with their own unique advantages and risks.

4. The Advantages Of Robotics In Aseptic Fill Finish 6/25/2020

   As you move into a future of diverse pipelines that present both great opportunities and challenges, consider utilizing a flexible solution like robotics that can be rapidly implemented into your facility.

5. Sanitary Mixing In Multi-Agitator Systems 2/4/2020

   Multi-shaft mixers are versatile systems used in the production of food, beverage, pharmaceutical and medical products. This bulletin discusses a few equipment features commonly supplied on multi-shaft mixers intended for sanitary applications.

6. High Containment Single-Use FIBC For Pharmaceutical Powder Handling 7/7/2020

   This webinar focuses on moving the HPAPI powders thru the entire process starting with chemical synthesis of the molecule to finishing in multiple solid dosage forms.

7. The Challenges Batch And Continuous Manufacturing Bring To Containment Product Design 3/13/2020

   Methods and techniques used in pharmaceutical manufacturing are broadly reviewed. There are two basic models of pharma manufacturing: batch and continuous. Both approaches are defined. It is concluded that both approaches have elements of the other. Generally speaking, many pharma manufacturing procedures are transitioning from the batch to the continuous approach.

8. Benefits Of A Modular Pharmaceutical Facility: From Raw Materials Handling To Final Packaging 9/2/2020

   With the COVID-19 pandemic’s effect on pharmaceutical supply chains, boosting local active pharmaceutical ingredients manufacturing and ensuring domestic drug production needs to be actively supported. But how to quickly implement a new state-of-the-art modular high potency pharmaceutical manufacturing plant and taking the opportunity to integrate the latest patient delivery systems?

9. Common Challenges And Solutions Of Equipment Ownership And Use 8/6/2020

   There are many factors to consider when tasked with acquiring the equipment needed to run a pharmaceutical facility. Being aware of every upfront costs is a must when determining optimal equipment ownership. See how state-of-the-art used equipment can be a great strategy for cost savings for businesses.

10. Enabling Enteric Protection And Rapid Release In The Upper Small Intestine 10/5/2020

    Enteric coatings have been utilized with oral drug products for more than 60 years to protect acid-sensitive APIs from gastric acids and prevent gastric irritation by aggressive APIs. However, for many complex drug products targeting the small intestine or ileocolonic region, enteric protection on its own is insufficient to maximize absorption and enhance bioavailability. A new and unique oral drug delivery technology could be the solution.