Insights On Solid Dose Manufacturing

1. Installation Of Powder Transfer System And Powder Blender To Achieve Sterility Level Requirements 9/2/2020

   A facility handled sterile blending and packing powder from a tilting filter dryer under sterile conditions. They were transferring the discharge of the tilting dryer by screw feeder and transferring into an agitated mixer. Discharging the mixer by a screw feeder into a packing system. They were encountering sterility loss through mechanical seals and docking of the dryer to the screw feeder and difficulties to clean and sterilize the system in place. A solution was a full automatice system including a transfer system, batchmixer and sampling device.

2. Selecting RABS vs. Isolators 1/13/2022

   We provide an attributes comparison of the primary strengths and weaknesses of the two systems in terms of infrastructure, performance, operation, cost, and compliance burden.

3. Leveraging An Integrated Network To Accelerate Spray Drying And Tableting Scale-Up 3/4/2022

   A biopharmaceutical company sought to develop a commercially-viable tablet formulation for use in phase 2 studies, utilizing spray drying for solubility enhancement.

4. Feeder Advancements Improve Cleanability And Automation 8/25/2020

   This webinar is designed to educate attendees on the newest criteria and engineered solutions available in feeding and material handling for quick and efficient product changeover.  

5. Setting Up The Lab To Ensure Personnel Safety 3/14/2022

   Here, we highlight some key factors to consider during lab setup and offer some general guidelines for identifying a biosafety cabinet that meets your workflow needs.

6. The Importance Of Automation For API Manufacturing: Bulk Handling, Dispensing, IBC Filling 9/1/2020

   An operation required manual filling of IBCs by using a flexible isolator installed on an upper floor with large amounts of excipients (lactose and micro cellulose)> 100 kg and only a small amount of APls of a few kilos. Operation was strenuous due to the large quantity of excipients to be handled in the isolator which lead to the damage of the flexible isolator and containment breach. Several equipment and process changes allowed them to see an increase of plant productivity.

7. How To Make Solid Dose Pharmaceutical Tablets 2/24/2022

   In this article, we cover the basics of manufacturing these tablets that start out in a research & development, independent lab, CDMO, or brand name manufacture.

8. Modular Pharma Facility: From Raw Materials To Final Packaging 9/2/2020

   How do you quickly implement a new state-of-the-art modular high-potency pharmaceutical manufacturing plant and take the opportunity to integrate the latest patient delivery systems?

9. Achieve High Containment, Reduce Cross Contamination Risk 2/15/2022

   In this paper we explore how single-use containment technology impacts capital spending and operating expenses in these workflows.

10. GKF 705: Fully Automatic Capsule Filling Machine 3/7/2022

    We deliver filling beyond your expectations with gentle handling of your capsules, reduction of product loss, and higher batch quality.