A Case Study In Sizing Nanoparticles

Interest in nanoparticles has risen consistently and rapidly in recent years, but one problem has remained; what is the "best" way to determine the size of these materials? In other words, what is the particle size of my nano materials? In this study, we wanted to investigate what viable options were available to measure these types of materials. There are several techniques commercially available, but we choose to look only at dynamic light scattering (DLS), Microscopy (SEM or TEM), and finally a calculation of the average particle size from a BET surface area measurement.