A Guide To USP <922> For Water Activity Determination
Pharmaceutical solids can come in contact with water during processing and are susceptible to water exchange with the surrounding environment during storage. Because this can lead to adverse effects on the pharmaceutical material, it is important to characterize and control the moisture present in the material. Standard moisture determination methods determine the total water content. However, water activity determination is increasingly being used in the pharmaceutical industry as evidenced by a new US Pharmacopeia draft chapter <922> Water Activity.
This webcast presents how a water activity measurement can be implemented to give insight into the impact of these reactions on critical product quality attributes including stability, dissolution rate, and physical properties of tablets, pills, and capsules, and other solid pharmaceutical material.
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