A Universal Workflow Approach For Single Cell Mass Spectrometry Based Proteomics

Single-cell proteomics is rapidly evolving, offering deeper insights into cellular heterogeneity and disease mechanisms. Explore a streamlined workflow using the Uno Single Cell Dispenser™ for mass spectrometry-based proteomics, comparing its performance to traditional FACS methods. The study demonstrates that the Uno dispenser delivers comparable protein identification results with reduced variability, faster setup, and gentler cell handling. Its disposable components minimize contamination risk, and its intuitive operation lowers the barrier for adoption in core facilities. The ability to co-dispense reagents and cells further simplifies sample preparation. These advantages make the Uno Single Cell Dispenser a compelling option for labs aiming to enhance reproducibility and throughput in single-cell proteomics.

For facilities seeking to modernize their SCP workflows, this application note offers practical insights and benchmarking data worth exploring.