Application Note

A Vibrating Capillary Dosing System: How Harro Höfliger's Microvibe Enables Fully Automatic Dosing For A Variety Of Powders

By Dr. Elke Sternberger-Rützel

Dosing microgram-level powder quantities poses severe rheological challenges, particularly when handling cohesive active ingredients without excipient carriers. Traditional volumetric dosing often leads to powder bridging, uneven fill weights, and frequent line stoppages. Vibrating capillary technology solves these issues by using piezo-driven fluidization to achieve continuous, weight-controlled powder dispensing into capsules, vials, or delivery devices. Independent evaluations across diverse excipient profiles reveal that dosing accuracy at microgram thresholds is governed primarily by fill mass rather than powder flow properties. Dynamic adjustments to vibration frequency and amplitude ensure precise dispensing while closed containment protects operators from potent substances. Review empirical data on weight-controlled vibrating capillary powder dosing performance.

Harro Höfliger designs, engineers and manufactures state-of-the-art production equipment for pharmaceutical and medical device clients around the world. Our global presence in automation technologies facilitates production in:

  • Medical Device Assembly
  • Parenteral Device Assembly
  • Pharmaceutical Dosing Technologies
  • Capsule Filling and Weighing
  • Cell & Gene Therapy Automation
  • Aseptic Applications
  • Packaging Equipment
  • Diagnostics Manufacturing
  • Surgical Suture Production
  • Inhalation Dosing and Assembly
  • Web Processing and Converting
  • Eye Care and Contact Lense Manufacturing
  • Wound Care, Transdermal, and Oral Dissolvable Film Production

Whether your application requires manufacturing, assembly, filling, sealing, packaging, technical consulting – or any combination of the above – Harro Höfliger brings 50+ years of expertise to each customer’s unique pharmaceutical and/or medical device project. No matter if your product is in the laboratory and development phase or it demands commercial production, our global team of engineers, designers, pharmacists, and customer service providers are equipped to support the success of each project, well into its future.

access the Application Note!

Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Pharmaceutical Online