Accu-Break Pharmaceuticals, Inc. Issued First Two Patents For Its Accu-Break Technologies

Accu-Break Pharmaceuticals, Inc. ("ABP"), a company with a suite of pharmaceutical tablet technologies for creating divisible dosage forms, announced recently the recent issuance of two patents covering its Accu-Break technologies. Tablets made in the Accu-Break format contain a drug-free layer that may be used as a break zone should the dose need to be adjusted. The technologies are intended to create pharmaceutical tablets that can be easily divided into precise doses to facilitate titration, dose adjustment and individualized dosing.

The first patent (U.S. 7,318,935) claims a layered immediate-release (IR) tablet having at least two different active ingredients segregated from each other by a drug-free layer. The innovative tablet design may be used to combine medications in a way that allows them to be administered together in a single tablet, as in traditional fixed-dose combination tablets, but also enables the two medications to be accurately separated if medically indicated simply by splitting the tablet through the drug-free layer. The invention also allows for the combination of active ingredients within a single tablet that are incompatible, providing a potential solution for useful combinations containing formulations that may be difficult to combine in a single tablet due to incompatibility reasons, among others.

The second patent (U.S. 7,329,418) also claims divisible tablets, but involves the creation of tablets that contain a half dose of the same active (or combination of the same actives) on each end of the tablet, separated by a drug-free break layer. Division of these tablets through the drug-free break layer would provide an accurate partial dose of the active(s), useful for titration and dose adjustment.

ABP's CEO, Allan S. Kaplan, Ph.D. (co-inventor of the patented technologies together with Lawrence Solomon, M.D.), stated, "The Company views the issuance of these patents as key to both our own product development and the worldwide licensing of our innovative tablet technologies. The granting of these patents should bode well for additional pending applications that cover, among other things, new and complimentary tablet technologies."

Dr. Kaplan continued, "Together with our recently announced strategic alliance agreement with Azopharma Development Group, we now offer patented technologies and a center of excellence to pharmaceutical companies wishing to develop their products utilizing the Accu-Break technologies."

ABP has additional patent applications currently under review or awaiting review by the United States Patent and Trademark Office. These additional applications include claims of varying scope, such as those containing from two to five (or more) layers, novel score patterns, and controlled-release embodiments.

About Accu-Break Pharmaceuticals, Inc.
ABP is developing Accu-Break technologies for pharmaceutical tablets. The Company believes that these technologies may allow physicians to better customize treatment for their patients and that tablets utilizing Accu-Break technologies will represent improved dosage forms for many types of medications. ABP is located at 1000 S. Pine Island Road, Suite 230, Plantation, FL 33324. The corporate website address is www.accubreak.com.

SOURCE: Accu-Break Pharmaceuticals, Inc.