Advancing Cell & Gene Therapies With Simple Western And Single-Cell Western

Cell & gene therapies promise innovative new treatments for severe diseases like cancer, autoimmune disease, muscular dystrophy, and hemoglobinopathies. Several cell & gene therapies products have been approved by the FDA, and more than 1000 are in clinical trials. Because they treat the underlying cause of diseases rather than just the symptoms, cell & gene therapies are attractive alternatives to traditional drug-based therapies.

To study and develop new cell & gene therapies, ProteinSimple, a Bio-Techne brand, offers Simple Western, which is a fully automated capillary immunoassay for the specific detection of target proteins in complex samples. The key value propositions of Simple Western include small sample size requirements (as little as 3 μL), high throughput, quick time to results (as little as 3 hours), highly quantitative data, and total protein detection.

This paper highlights how Simple Western and Single-Cell Western are instrumental in developing cell & gene therapies for Duchenne muscular dystrophy, lupus, cystic fibrosis, and sickle-cell disease. We also include references to other noteworthy cell & gene therapy publications that harness the power of Simple Western and Single-Cell Western.