An Introduction To Isolated Robotic Aseptic Filling Systems: GENiSYS C

During this presentation from the September 2023 Virtual Pharma Expo, Josh Russell, VP of Sales and Marketing, AST, demonstrated the Genesis C aseptic filling system. AST's GENiSYS® C is an advanced and compact filling and closing system designed for the automated processing of nested, custom, and ready-to-use vials, syringes, and cartridges. With many features found in large-scale filling machines, the GENiSYS C's compact footprint makes it exceptionally well-suited for small-scale applications including R&D, process development, engineering runs, niche product manufacturing, and even cGMP clinical and small-batch commercial manufacturing.

Eliminating waste is the key to successful small-batch processing. Essential operations such as pump calibration, ongoing fill volume checks, and residual product hold-up in the fluid path all contribute to wasted product material. The GENiSYS C's in-process control system addresses these concerns by enabling 100% fill weight inspection and real-time filling directly on the electronic weigh scale. This not only eliminates improperly filled containers but also minimizes product hold-up at the end of the batch, maximizing product yield. When combined with the AST View Electronic Batch Record (EBR) system, users gain a comprehensive record of the dispensed product.