Recloseable Multi-Dose Containers From bottelpack® Blow/Fill/Seal Aseptic Machines

By rommelag

From the beginning of the 1970's, the bottelpack system established itself very rapidly in the field of eyedrops and ocular medicine for volumes situated generally between 5 and 15 ml.

These plastic bottles were blown and sealed under sterile conditions. The bottle-neck had a standard thread fitted with a piercing cap.

When the product was to be used, the cap was screwed down as far as it would go. The spike inside the cap pierced the upper membrane in the neck of the bottle.

The regular flow and size of the drops depended upon the diameter of the hole and the pressure exerted by the fingers. Excessive, continuous pressure transformed the flow drops into a spray.

This system was simple, safe, practical and efficient. It was used for many years and gave complete satisfaction for the great majority of products.

However, it was considered inadequate for special products which required strict observance of dosage instructions.