Capsule Filling With QUANTOS - For Pre-Clinical Trials

By Mettler-Toledo AG, Process Analytical, Inc.

Discover how a top pharmaceutical company automated the slow, unsafe and expensive process of capsule filling for their pre-clinical trials.

The main goals of pre-clinical studies are to determine a product's ultimate safety profile. Studies involve in vitro and in vivo experiments, through dynamic weighing, using wideranging doses of the study drug to obtain preliminary data. Depending on the nature of drug and test subject, new pharmaceuticals are often administered via gelatine capsules, where the fill weight of each capsule must be accurately calculated and prepared according to the test object's weight. This involves manually weighing in highly potent, hazardous substances precisely with a spatula.