Case Study

CAR-T And Laminar Flow Glovebox Isolators

Source: Germfree
Laminar Flow Glovebox Isolator LFGI

Germfree recently supplied a cell therapy aseptic containment isolator for a CAR-T cell therapy facility in New Jersey. The isolators were utilized to protect operators during the transfer of the lentivirus and create a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking. These isolators are specifically designed to maintain an aseptic environment and ensure the safety of operators.

The solution provided by Germfree meets the stringent requirements of aseptic processing. Their Laminar Flow Glovebox Isolator (LFGI) functions as a containment system and can operate under both negative and positive pressure. The system not only safeguards operators during the lentivirus transfer but also provides a controlled environment for various processes. It complies with ISO 5 conditions and maintains a pressure differential between the main chamber and the room. Additionally, the LFGI is equipped with HEPA filters for efficient particle removal. It is designed for continuous operation and can be customized to meet specific needs.

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