Poster

Characterization & Delivery Of Ultra-Viscous & Non-Newtonian Formulations

Source: SMC Ltd.

By James Hance, Senior Device Development Engineer, Oval Medical Technologies

GettyImages-893884884-lab-research-team

The most recent innovations in injectable formulations are pushing the limit of performance and design of many traditional drug-delivery platforms. We are seeing a significant increase in the number of highly viscous (HV) formulations (100-1000 cP) and ultra high-viscous formulations (UHV) (1,000-100,000+ cP) in the field of Longacting injectables and biologics. In addition to high-viscosity these formulations often exhibiting non-Newtonian flow characteristics, or in the case of suspensions, ‘clogging’ characteristics. A vital step in successful and optimal autoinjector device platform development is to gain a solid understanding of these characteristics at the earliest stage. This poster discusses how Oval goes about this process with the use of the innovative Injection Characterisation System (ICS).

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