Characterization & Delivery Of Ultra-Viscous & Non-Newtonian Formulations
By James Hance, Senior Device Development Engineer, Oval Medical Technologies
The most recent innovations in injectable formulations are pushing the limit of performance and design of many traditional drug-delivery platforms. We are seeing a significant increase in the number of highly viscous (HV) formulations (100-1000 cP) and ultra high-viscous formulations (UHV) (1,000-100,000+ cP) in the field of Longacting injectables and biologics. In addition to high-viscosity these formulations often exhibiting non-Newtonian flow characteristics, or in the case of suspensions, ‘clogging’ characteristics. A vital step in successful and optimal autoinjector device platform development is to gain a solid understanding of these characteristics at the earliest stage. This poster discusses how Oval goes about this process with the use of the innovative Injection Characterisation System (ICS).
Get unlimited access to:
Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.