Characterizing Drug Substance Properties Early Can Optimize Drug Product Formulation

By Anil Kane, PhD, MBA Executive Director, Global Head of Formulation Development, Thermo Fisher Scientific

Molecules continue to get more challenging from the perspective of solubility, bioavailability, and exposure. Advances in formulation technologies continue to provide more solutions. Establishing effective communications between DS chemists and DP formulators manage the risks and maximize the rewards of transforming less soluble and less bioavailable molecules into effective new drugs.