Chilsonator®
The Chilsonator® (Dry Granulation/Roll Compactor)
Pharmaceutical products typically contain a blend of active material with additional excipients such as flow agents, disintegrating agents, binders, etc. These are typically fine powders with diverse characteristics. Conditioning of these materials is required for effective tabletting, capsule filling or subsequent processing.
Dry granulation is a process which creates free flowing granules without the need of adding binders or water.
How does it work?
The basic concept of compaction (seen in the illustration) is to force fine powders between two counter rotating rolls. As the volume decreases through the region of maximum pressure, the material is formed into a solid compact or sheet.
Some of the factors controlling the compaction process are roll surface, diameter, peripheral speed, separating force or pressure capabilities, feed screw design, and basic compaction characteristics of material being processed.
In most applications, the product compacted by the Chilsonator must be granulated to a uniform particle size distribution. This can be most efficiently achieved with a FitzMill granulator, which is designed with maximum flexibility enabling control of the size reduction process.
Recycle System - In order to eliminate essentially all fines and overs it is possible to design the dry granulation system to include a screener and recycle system. This provides tremendous control of the final particle size and density.